Hajime Iizuka

Overview

Best Publications

• Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)

  Masato Matsuki;Fumiyoshi Yamashita;Akemi Ishida-Yamamoto;Keiko Yamada

  352
  Citations

• The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.

  Kazumitsu Sugiura;Akemi Takemoto;Michiya Yamaguchi;Hidetoshi Takahashi

  305
  Citations

• Epidemiology of psoriasis and palmoplantar pustulosis: a nationwide study using the Japanese national claims database

  Kiyoshi Kubota;Yukari Kamijima;Tsugumichi Sato;Nobuhiro Ooba

  301
  Citations

• A randomized double-blind trial of intravenous immunoglobulin for pemphigus

  Masayuki Amagai;Shigaku Ikeda;Hiroshi Shimizu;Hajime Iizuka

  297
  Citations

• Serum cytokines and growth factor levels in Japanese patients with psoriasis

  H. Takahashi;H. Tsuji;Y. Hashimoto;A. Ishida-Yamamoto

  259
  Citations

• LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum.

  Akemi Ishida-Yamamoto;Céline Deraison;Chrystelle Bonnart;Emmanuelle Bitoun

  211
  Citations

• The Molecular Pathology of Progressive Symmetric Erythrokeratoderma: A Frameshift Mutation in the Loricrin Gene and Perturbations in the Cornified Cell Envelope

  Akemi Ishida-Yamamoto;John A. McGrath;HaMut Lam;Hajime Iizuka

  207
  Citations

• Epidermal lamellar granules transport different cargoes as distinct aggregates.

  Akemi Ishida-Yamamoto;Michel Simon;Mari Kishibe;Yuki Miyauchi

  185
  Citations

• Decreased Deiminated Keratin K1 in Psoriatic Hyperproliferative Epidermis

  Akemi Ishida-Yamamoto;Tatsuo Senshu;Hidetoshi Takahashi;Kyoichi Akiyama

  167
  Citations

• Structural organization of cornified cell envelopes and alterations in inherited skin disorders.

  Akemi Ishida-Yamamoto;Hajime Iizuka

  165
  Citations

• Plasma adiponectin and leptin levels in Japanese patients with psoriasis.

  H. Takahashi;H. Tsuji;I. Takahashi;Y. Hashimoto

  160
  Citations

• Psoriasis and metabolic syndrome

  Hidetoshi Takahashi;Hajime Iizuka

  153
  Citations

• Loricrin Mutation in Vohwinkel’s Keratoderma Is Unique to the Variant with Ichthyosis

  Bernhard P. Korge;Akemi Ishida-Yamamoto;Claudia Pünter;Patricia J.C. Dopping-Hepenstal

  138
  Citations

• Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis.

  Hidetoshi Takahashi;Masaki Ibe;Satoshi Nakamura;Akemi Ishida-Yamamoto

  135
  Citations

• Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma

  Naoya Yamazaki;Yoshio Kiyohara;Hisashi Uhara;Hajime Iizuka

  135
  Citations

• Patients with palmoplantar pustulosis have increased IL-17 and IL-22 levels both in the lesion and serum.

  Masamoto Murakami;Eva Hagforsen;Vera Morhenn;Akemi Ishida-Yamamoto

  132
  Citations

• Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death.

  Hajime Iizuka;Hidetoshi Takahashi;Masaru Honma;Akemi Ishida-Yamamoto

  123
  Citations

• Epidermolysis bullosa acquisita sera react with distinct epitopes on the NC1 and NC2 domains of type VII collagen: study using immunoblotting of domain-specific recombinant proteins and postembedding immunoelectron microscopy.

  N. Ishii;M. Yoshida;Y. Hisamatsu;A. Ishida-Yamamoto

  118
  Citations

• Podoplanin expression in wound and hyperproliferative psoriatic epidermis: regulation by TGF-β and STAT-3 activating cytokines, IFN-γ, IL-6, and IL-22.

  Masaru Honma;Masako Minami-Hori;Hidetoshi Takahashi;Hajime Iizuka

  117
  Citations

• Similarly potent action of 1,25-dihydroxyvitamin D3 and its analogues, tacalcitol, calcipotriol, and maxacalcitol on normal human keratinocyte proliferation and differentiation

  Hidetoshi Takahashi;Masaki Ibe;Motoshi Kinouchi;Akemi Ishida-Yamamoto

  116
  Citations