World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
20748
World Ranking
13537
National Ranking
244

Overview

François Fuks is affiliated with the Université Libre de Bruxelles in Belgium and specializes in the broad field of Biochemistry, Genetics, and Molecular Biology, with a concentration on Molecular Biology. Their research interests include cancer research, genetics, and aspects of endocrinology, diabetes, and metabolism.

The main topics covered in their work encompass RNA modifications and cancer, epigenetics and DNA methylation, cancer-related molecular mechanisms and gene regulation, RNA research and splicing, RNA and protein synthesis mechanisms, and cancer genomics and diagnostics.

Fuks has published extensively, with notable recent papers including:

  • Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation, 2020, Nature Communications
  • Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors, 2021, Nature Cancer
  • SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer, 2023, Molecular Cell
  • Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors, 2022, Nature Cell Biology
  • Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation, 2025, Cell

Frequent co-authors in Fuks's publications include Emilie Calonne, Martin Bizet, Rachel Deplus, Jana Jeschke, and Jie Lan.

The primary venues for their work include bioRxiv (Cold Spring Harbor Laboratory), Clinical Epigenetics, Epigenetics, Current Opinion in Genetics & Development, and Nature Structural & Molecular Biology.

Best Publications

  • The Polycomb group protein EZH2 directly controls DNA methylation

    Emmanuelle Viré;Carmen Brenner;Rachel Deplus;Loïc Blanchon

  • The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation

    François Fuks;Paul J. Hurd;Daniel Wolf;Xinsheng Nan

  • DNA methyltransferase Dnmt1 associates with histone deacetylase activity.

    François Fuks;Wendy A. Burgers;Alexander Brehm;Luke Hughes-Davies

  • Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor

    Luciano Di Croce;Veronica A. Raker;Massimo Corsaro;Francesco Fazi

  • The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

    François Fuks;Paul J. Hurd;Rachel Deplus;Tony Kouzarides

  • DNA methylation and histone modifications: teaming up to silence genes.

    François Fuks

  • Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

    François Fuks;Wendy A. Burgers;Nadia Godin;Masataka Kasai

  • SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

    Soufiane Boumahdi;Gregory Driessens;Gaelle Lapouge;Sandrine Rorive

  • Evaluation of the Infinium Methylation 450K technology.

    Sarah Dedeurwaerder;Matthieu Defrance;Emilie Calonne;Hélène Denis

  • Myc represses transcription through recruitment of DNA methyltransferase corepressor

    Carmen Brenner;Rachel Deplus;Céline Didelot;Axelle Loriot

  • EMSY Links the BRCA2 Pathway to Sporadic Breast and Ovarian Cancer

    Luke Hughes-Davies;David Huntsman;Margarida Ruas;Francois Fuks

  • De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

    Silvina Epsztejn-Litman;Nirit Feldman;Monther Abu-Remaileh;Yoel Shufaro

  • TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

    Rachel Deplus;Benjamin Delatte;Marie K Schwinn;Matthieu Defrance

  • DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

    Michael Volkmar;Sarah Dedeurwaerder;Daniel A Cunha;Matladi N Ndlovu

  • Regulation of mammalian DNA methyltransferases: a route to new mechanisms.

    Hélène Denis;Matladi N Ndlovu;François Fuks

  • Transcriptome-wide distribution and function of RNA hydroxymethylcytosine

    Benjamin Delatte;Fei Wang;Long Vo Ngoc;Evelyne Collignon

  • Viral oncoproteins target the DNA methyltransferases.

    W A Burgers;L Blanchon;S Pradhan;Y de Launoit

  • The Ten-Eleven Translocation-2 ( TET2 ) gene in hematopoiesis and hematopoietic diseases

    Éric Solary;Olivier Bernard;Ayalew Tefferi;François Fuks

  • DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

    Raajit Rampal;Altuna Alkalin;Altuna Alkalin;Jozef Madzo;Aparna Vasanthakumar

  • Erratum: The Polycomb group protein EZH2 directly controls DNA methylation

    Emmanuelle Viré;Carmen Brenner;Rachel Deplus;Loïc Blanchon

Frequent Co-Authors

Christos Sotiriou
Christos Sotiriou Université Libre de Bruxelles
Tony Kouzarides
Tony Kouzarides University of Cambridge
Mingzhou Guo
Mingzhou Guo Chinese PLA General Hospital
James G. Herman
James G. Herman University of Pittsburgh
Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Luciano Di Croce
Luciano Di Croce Centre for Genomic Regulation
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Miriam Cnop
Miriam Cnop Université Libre de Bruxelles
Mario F. Fraga
Mario F. Fraga University of Oviedo
Stanislas Goriely
Stanislas Goriely Université Libre de Bruxelles

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens the door to diverse online degrees and evolving career paths within healthcare and the sciences. Many professionals choose to advance their education through flexible, online programs that fit their work-life balance and career goals. For those already holding a master's degree in nursing, the fastest post master's fnp certificate programs offer a swift route to becoming a Family Nurse Practitioner.

Allied health and nutrition remain high-growth fields. Individuals interested in nutrition can consider an online nutritionist degree, which can lead to careers in dietary planning, wellness coaching, or public health education. Registered nurses looking to advance may explore rn to bsn online programs, which provide a convenient pathway to expand clinical skills and qualify for leadership roles.

Aspiring healthcare administrators can pursue an online masters in healthcare management, equipping them with skills for management and operational roles in medical settings. These online options empower students and professionals with flexibility and the credentials needed to thrive in the growing fields of biology, biochemistry, and healthcare.

Best Scientists Citing François Fuks

Trending Scientists

Recently Published Articles