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Alfred Singer

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 84 1366 1246 700 626 250 26916

Alfred Singer publications per year

The chart shows the history of publications by Alfred Singer between 1977 and 2024, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Alfred Singer published across 48 years, from 1977 to 2024, averaging 5.3 papers a year. Output peaked at 17 publications in 1994. 3 of the 255 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1977 to 2024. Vertical axis: number of publications, 0 to 17. Peak 17 publications in 1994. 1977: 2 publications 1978: 4 publications 1979: 4 publications 1980: 10 publications 1981: 10 publications 1982: 13 publications 1983: 15 publications 1984: 5 publications 1985: 8 publications 1986: 8 publications 1987: 6 publications 1988: 13 publications 1989: 13 publications 1990: 8 publications 1991: 5 publications 1992: 7 publications 1993: 5 publications 1994: 17 publications 1995: 8 publications 1996: 3 publications 1997: 7 publications 1998: 1 publication 1999: 4 publications 2000: 5 publications 2001: 2 publications 2002: 4 publications 2003: 4 publications 2004: 4 publications 2005: 2 publications 2006: 4 publications 2007: 4 publications 2008: 2 publications 2009: 2 publications 2010: 4 publications 2011: 2 publications 2012: 9 publications 2013: 3 publications 2014: 6 publications 2015: 3 publications 2016: 3 publications 2017: 3 publications 2018: 3 publications 2019: 3 publications 2020: 2 publications 2021: 0 publications 2022: 2 publications 2023: 2 publications 2024: 1 publication
1977 2024

255 publications in total across all disciplines

View publications per year as a table
Alfred Singer: publications per year, 1977 to 2024
Year Publications
1977 2
1978 4
1979 4
1980 10
1981 10
1982 13
1983 15
1984 5
1985 8
1986 8
1987 6
1988 13
1989 13
1990 8
1991 5
1992 7
1993 5
1994 17
1995 8
1996 3
1997 7
1998 1
1999 4
2000 5
2001 2
2002 4
2003 4
2004 4
2005 2
2006 4
2007 4
2008 2
2009 2
2010 4
2011 2
2012 9
2013 3
2014 6
2015 3
2016 3
2017 3
2018 3
2019 3
2020 2
2021 0
2022 2
2023 2
2024 1
Total 255
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Alfred Singer publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Alfred Singer sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 242–251 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 250 publications — 51st percentile

51% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160 250
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Alfred Singer D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Alfred Singer sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 84–85 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 84 D-Index — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121 84
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
Download as CSV

Overview

Alfred Singer is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the field of Immunology and Microbiology, with a specialized emphasis on Immunology. This research spans several interconnected topics, including T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, CAR-T cell therapy research, and Reproductive System and Pregnancy.

The scientist has contributed to numerous publications across several notable venues, with repeated appearances in Nature Immunology and Frontiers in Immunology. Other publication venues include Science, The Journal of Immunology, and Clinical and Translational Medicine.

Recent papers authored or coauthored by Alfred Singer include the following:

  • How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion, 2023, Nature Immunology
  • Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus, 2022, Nature Immunology
  • CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus, 2023, Science
  • Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155, 2020, The Journal of Immunology
  • Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus, 2020, Frontiers in Immunology

Frequent coauthors collaborating with Alfred Singer include:

  • Xuguang Tai
  • Abhisek Bhattacharya
  • Amala Alag
  • Terry I. Guinter
  • Jinghua Lu

The scientist's work covers critical aspects of the immune system, particularly focusing on T-cell development, tolerance, and lineage fate decisions within the thymus. Their studies address the molecular mechanisms by which autoreactive thymocytes differentiate into various T cell subsets, as well as the role of MHC-independent T cell receptors in antigen recognition.

Best Publications

  • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

    Shimon Sakaguchi;Noriko Sakaguchi;Masanao Asano;Misako Itoh

  • CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

    Xuguang Tai;Michelle Cowan;Lionel Feigenbaum;Alfred Singer

  • Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.

    Alfred Singer;Stanley Adoro;Jung-Hyun Park

  • Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival.

    Jung-Hyun Park;Qing Yu;Batu Erman;Jacob S. Appelbaum

  • Cellular basis of skin allograft rejection: an in vivo model of immune-mediated tissue destruction.

    and A S Rosenberg;A Singer

  • Crosstalk in the mouse thymus.

    Willem van Ewijk;Elisabeth W. Shores;Alfred Singer

  • Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

    J A Punt;B A Osborne;Y Takahama;S O Sharrow

  • Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells

    Enrico Brugnera;Avinash Bhandoola;Ricardo Cibotti;Qing Yu

  • Basis of CTLA-4 function in regulatory and conventional CD4+ T cells

    Xuguang Tai;François Van Laethem;Leonid Pobezinsky;Terry Guinter

  • Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: A new perspective on thymic commitment and selection

    Harumi Suzuki;Jennifer A. Punt;Lawrence G. Granger;Alfred Singer

  • T cell development in mice that lack the zeta chain of the T cell antigen receptor complex

    Paul E. Love;Elizabeth W. Shores;Mark D. Johnson;Michel L. Tremblay

  • Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment.

    Elizabeth W. Shores;Willem Van Ewijk;Alfred Singer

  • Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

    Xuguang Tai;Batu Erman;Amala Alag;Jie Mu

  • Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection.

    A S Rosenberg;T Mizuochi;S O Sharrow;A Singer

  • Deletion of CD4 and CD8 Coreceptors Permits Generation of αβT Cells that Recognize Antigens Independently of the MHC

    François Van Laethem;Sophia D. Sarafova;Jung-Hyun Park;Xuguang Tai

  • New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision

    Alfred Singer

  • 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

    Jung-Hyun Park;Stanley Adoro;Stanley Adoro;Philip J Lucas;Sophia D Sarafova;Sophia D Sarafova

  • Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.

    D L Wiest;L Yuan;J Jefferson;P Benveniste

  • Self recognition in allogeneic radiation bone marrow chimeras. A radiation-resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells.

    Alfred Singer;Karen S. Hathcock;Richard J. Hodes

  • Clonal deletion and the fate of autoreactive thymocytes that survive negative selection

    Leonid A Pobezinsky;Georgi S Angelov;Xuguang Tai;Susanna Jeurling

  • Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus

    Zvi Grossman;Alfred Singer

Frequent Co-Authors

Susan O. Sharrow
Susan O. Sharrow National Institutes of Health
Richard J. Hodes
Richard J. Hodes National Institutes of Health
Lionel Feigenbaum
Lionel Feigenbaum Science Applications International Corporation (United States)
Avinash Bhandoola
Avinash Bhandoola National Institutes of Health
Yousuke Takahama
Yousuke Takahama National Institutes of Health
Toshinori Nakayama
Toshinori Nakayama Chiba University
Dinah S. Singer
Dinah S. Singer National Institutes of Health
Paul E. Love
Paul E. Love National Institutes of Health
Ada M. Kruisbeek
Ada M. Kruisbeek DCprime
Peter D. Sun
Peter D. Sun National Institutes of Health

External Links

Wikipedia of Alfred Singer Personal website of Alfred Singer

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Jonathan Sprent

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Garvan Institute of Medical Research

Publications: 59

Paul E. Love

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National Institutes of Health

Publications: 52

Arthur Weiss

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Publications: 51

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Publications: 43

Kristin A. Hogquist

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Publications: 40

Toshinori Nakayama

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Publications: 39

John W. Kappler

John W. Kappler

National Jewish Health

Publications: 36

Ronald N. Germain

Ronald N. Germain

National Institute of Allergy and Infectious Diseases

Publications: 36

Ichiro Taniuchi

Ichiro Taniuchi

RIKEN Center for Integrative Medical Sciences

Publications: 35

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Juan Carlos Zúñiga-Pflücker

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Publications: 34

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Publications: 32

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Publications: 32

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Nicholas R. J. Gascoigne

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Publications: 32

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