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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9627
World Ranking
15177
National Ranking
6346

Overview

Dinah S. Singer is affiliated with the National Institutes of Health in the United States. Their research spans areas primarily within Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. Subfields of study include Molecular Biology, Oncology, Biomedical Engineering, Public Health, Environmental and Occupational Health, and Genetics.

The scientist's research topics cover a range focused on cellular and molecular mechanisms, including:

  • Protein Degradation and Inhibitors
  • Genomics and Chromatin Dynamics
  • Ubiquitin and Proteasome Pathways
  • Chromatin Remodeling and Cancer
  • Epigenetics and DNA Methylation
  • Health and Medical Research Impacts
  • RNA Research and Splicing

Dinah S. Singer has contributed to multiple publications, notably in high-impact journals such as Cell, Nature Medicine, and Proceedings of the National Academy of Sciences. Recent publications include:

  • MYC protein stability is negatively regulated by BRD4, 2020, Proceedings of the National Academy of Sciences
  • A Blueprint for Characterizing Senescence, 2020, Cell
  • A new phase of the Cancer Moonshot to end cancer as we know it, 2022, Nature Medicine
  • Progress and potential: The Cancer Moonshot, 2021, Cancer Cell
  • BET Inhibitors Target the SCLC-N Subtype of Small-Cell Lung Cancer by Blocking NEUROD1 Transactivation, 2022, Molecular Cancer Research

The scientist frequently publishes research in venues including bioRxiv (Cold Spring Harbor Laboratory), Cancer Discovery, Cancer Cell, Science Advances, and Molecular Cell.

Frequent collaborators in their research work include Ballachanda N. Devaiah, Qingrong Chen, Daoud Meerzaman, Amit Kumar Singh, and Jie Mu. These coauthors have contributed jointly on multiple occasions, indicating ongoing collaborative efforts.

Best Publications

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

    Ballachanda N. Devaiah;Brian A. Lewis;Natasha Cherman;Michael C. Hewitt

  • BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

    Ballachanda N Devaiah;Chanelle Case-Borden;Anne Gegonne;Chih Hao Hsu

  • A community computational challenge to predict the activity of pairs of compounds

    Mukesh Bansal;Mukesh Bansal;Jichen Yang;Charles Karan;Michael P Menden

  • RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.

    Laura Baranello;Damian Wojtowicz;Kairong Cui;Ballachanda N. Devaiah

  • Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

    Xuguang Tai;Batu Erman;Amala Alag;Jie Mu

  • Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides.

    Koichi Suzuki;Atsumi Mori;Ken J. Ishii;Jun Saito

  • Autoregulation of thyroid-specific gene transcription by thyroglobulin

    Koichi Suzuki;Stefano Lavaroni;Atsumi Mori;Masanori Ohta

  • HIV-1 Tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes

    J. D. Weissman;J. A. Brown;T. K. Howcroft;Jae Hwang

  • Regulation of the expression of class I MHC genes.

    D. S. Singer;J. E. Maguire

  • Resistance of MHC class I-deficient mice to experimental systemic lupus erythematosus

    Edna Mozes;Leonard D. Kohn;Fran Hakim;Dinah S. Singer

  • Core promoters in transcription: old problem, new insights

    Ananda L. Roy;Dinah S. Singer

  • Transcriptional Coactivator, CIITA, Is an Acetyltransferase that Bypasses a Promoter Requirement for TAFII250

    Aparna Raval;T. Kevin Howcroft;Jocelyn D. Weissman;Susan Kirshner

  • Thymosin-α1 regulates MHC class I expression in FRTL-5 cells at transcriptional level

    Cesidio Giuliani;Giorgio Napolitano;Antonio Mastino;Simonetta Di Vincenzo

  • Characterization of a porcine genomic clone encoding a major histocompatibility antigen: expression in mouse L cells.

    D S Singer;R D Camerini-Otero;M L Satz;B Osborne

  • CIITA and Its Dual Roles in MHC Gene Transcription

    Ballachanda N. Devaiah;Dinah S. Singer

  • A Spontaneously Arising Mutation in the DLAARN Motif of Murine ZAP-70 Abrogates Kinase Activity and Arrests Thymocyte Development

    David L Wiest;Jennifer M Ashe;T.Kevin Howcroft;Hon-Man Lee

  • Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon.

    M Saji;J Moriarty;T Ban;D S Singer

  • Erythropoietic Differentiation in Colonies of Cells Transformed by Friend Virus

    Dinah Singer;Marvin Cooper;George M. Maniatis;Paul A. Marks

  • MYC protein stability is negatively regulated by BRD4.

    Ballachanda N. Devaiah;Jie Mu;Ben Akman;Sheetal Uppal

Frequent Co-Authors

Leonard D. Kohn
Leonard D. Kohn National Institutes of Health
Alfred Singer
Alfred Singer National Institutes of Health
Edna Mozes
Edna Mozes Weizmann Institute of Science
Minho Shong
Minho Shong Korea Advanced Institute of Science and Technology
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Kenneth H. Buetow
Kenneth H. Buetow Arizona State University
Fred D. Ledley
Fred D. Ledley Bentley University
Stuart Rudikoff
Stuart Rudikoff National Institutes of Health
John N. Brady
John N. Brady National Institutes of Health
Aviv Regev
Aviv Regev Genentech

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