D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 66 Citations 13,376 128 World Ranking 1818 National Ranking 932

Research.com Recognitions

Awards & Achievements

1959 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

His primary scientific interests are in Molecular biology, Transcription factor, Cancer research, Gene expression profiling and Transactivation. His Molecular biology study incorporates themes from Human T cell lymphotropic virus type 1, Mutation, Promoter, RNA polymerase II and Long terminal repeat. His RNA polymerase II research is multidisciplinary, incorporating perspectives in Chromatin, Transcription factor II D and Transcription preinitiation complex.

John N. Brady has researched Transcription factor in several fields, including Acetyltransferase and Regulation of gene expression. His Cancer research research integrates issues from Carcinogenesis, Cell cycle, Immunology and Virology. The Transactivation study combines topics in areas such as PCAF and Cell biology.

His most cited work include:

  • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. (856 citations)
  • Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. (609 citations)
  • Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma (512 citations)

What are the main themes of his work throughout his whole career to date?

John N. Brady focuses on Molecular biology, Transcription, Transactivation, Transcription factor and Virology. His Molecular biology research includes elements of Human T cell lymphotropic virus type 1, Promoter, RNA polymerase II, General transcription factor and Long terminal repeat. His Transcription research is multidisciplinary, incorporating elements of RNA, Gene expression, Binding site and Cell biology.

John N. Brady has included themes like HIV Long Terminal Repeat, Jurkat cells, PCAF, Viral replication and Sp1 transcription factor in his Transactivation study. His Transcription factor research includes themes of Regulation of gene expression and Activator. His study in the field of Virus is also linked to topics like Kaposi's sarcoma-associated herpesvirus.

He most often published in these fields:

  • Molecular biology (59.55%)
  • Transcription (28.65%)
  • Transactivation (23.60%)

What were the highlights of his more recent work (between 2002-2014)?

  • Molecular biology (59.55%)
  • Cancer research (11.80%)
  • Gene expression profiling (8.43%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Molecular biology, Cancer research, Gene expression profiling, Gene expression and Cell biology. His work deals with themes such as Chromatin immunoprecipitation, Transcription, Transactivation, RNA polymerase II and Transcription factor II D, which intersect with Molecular biology. His RNA polymerase II research incorporates themes from Cyclin T1, Transcription factor and P-TEFb.

His Cancer research study combines topics from a wide range of disciplines, such as Papillary serous, Virology, Carcinogenesis, Tumor suppressor gene and Cell cycle. He interconnects Phenotype, Regulation of gene expression, Ovarian cancer and Immunology in the investigation of issues within Gene expression profiling. His Gene expression study combines topics in areas such as Internal medicine and Serous fluid.

Between 2002 and 2014, his most popular works were:

  • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. (856 citations)
  • Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. (609 citations)
  • Characterization and isolation of stem cell–enriched human hair follicle bulge cells (491 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

His scientific interests lie mostly in Cancer research, Molecular biology, Gene expression profiling, Cell biology and Ovarian cancer. His Cancer research study integrates concerns from other disciplines, such as PI3K/AKT/mTOR pathway, Protein kinase B, Signal transduction, Immunology and Cell cycle. The concepts of his Molecular biology study are interwoven with issues in Immunoprecipitation, Chromatin immunoprecipitation, Hair follicle, Keratinocyte and Transcription factor II D.

His research investigates the link between Transcription factor II D and topics such as Bromodomain that cross with problems in Chromatin. His research in Gene expression profiling intersects with topics in Carcinogenesis, Microarray and Microarray analysis techniques. The study incorporates disciplines such as RNA polymerase II and Transactivation in addition to Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.

Moon Kyoo Jang;Kazuki Mochizuki;Meisheng Zhou;Ho-Sang Jeong.
Molecular Cell (2005)

1355 Citations

Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

Barbara Ensoli;Rita Gendelman;Phillip Markham;Valeria Fiorelli.
Nature (1994)

780 Citations

Characterization and isolation of stem cell–enriched human hair follicle bulge cells

Manabu Ohyama;Atsushi Terunuma;Christine L. Tock;Michael F. Radonovich.
Journal of Clinical Investigation (2005)

762 Citations

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

Rong Zeng;Rosanne Spolski;Steven E. Finkelstein;Sang Kon Oh.
Journal of Experimental Medicine (2005)

715 Citations

Phosphorylation of p53 serine 15 increases interaction with CBP

Paul F. Lambert;Fatah Kashanchi;Michael F. Radonovich;Ramin Shiekhattar.
Journal of Biological Chemistry (1998)

546 Citations

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice.

Changqing Ju;Timothy P. Reilly;Mohammed Bourdi;Michael F. Radonovich.
Chemical Research in Toxicology (2002)

406 Citations

Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.

Tomas Bonome;Ji Young Lee;Dong Choon Park;Mike Radonovich.
Cancer Research (2005)

369 Citations

A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer.

Tomas Bonome;Douglas A. Levine;Joanna H. Shih;Mike Randonovich.
Cancer Research (2008)

357 Citations

Identification of Kaposin (Open Reading Frame K12) as a Human Herpesvirus 8 (Kaposi’s Sarcoma-Associated Herpesvirus) Transforming Gene

Sumitra Muralidhar;Anne M. Pumfery;Morad Hassani;M. Reza Sadaie.
Journal of Virology (1998)

354 Citations

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

Meisheng Zhou;Matthew A. Halanski;Michael F. Radonovich;Fatah Kashanchi;Fatah Kashanchi.
Molecular and Cellular Biology (2000)

330 Citations

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