Biochemistry, Pharmacology, Microsome, Metabolite and Acetaminophen are his primary areas of study. His Biochemistry research incorporates themes from Molecular biology, Halothane and Drug. His work carried out in the field of Pharmacology brings together such families of science as Gene expression profiling, Toxicity and Halothane hepatitis.
His studies in Microsome integrate themes in fields like Cytochrome, Antibody, Cysteine and Stereochemistry. His Metabolite research includes themes of Chromatography, Chloroform and Phosgene. In his study, Cytotoxic T cell is inextricably linked to Immunology, which falls within the broad field of Liver injury.
Lance R. Pohl mainly focuses on Biochemistry, Microsome, Immunology, Pharmacology and Metabolite. Lance R. Pohl has researched Biochemistry in several fields, including Chromatography, Halothane and In vivo. The study incorporates disciplines such as Isoflurane, Internal medicine, Hepatitis and Antibody, Hapten in addition to Halothane.
His Microsome study integrates concerns from other disciplines, such as Hydroxylation, Cytochrome, Stereochemistry and Metabolism. He works mostly in the field of Immunology, limiting it down to concerns involving Liver injury and, occasionally, Acetaminophen. The Pharmacology study combines topics in areas such as Enflurane and Toxicity.
Immunology, Liver injury, Acetaminophen, Pharmacology and Toxicity are his primary areas of study. As part of one scientific family, Lance R. Pohl deals mainly with the area of Immunology, narrowing it down to issues related to the Drug, and often Immune system, Antigen and Function. His Liver injury research includes elements of Acquired immune system, Eosinophilia and Antibody.
His work deals with themes such as Cell culture, Halothane, Natural killer cell and Hepatitis, which intersect with Pharmacology. His Toxicity research is multidisciplinary, relying on both Heat shock protein, Toxicogenomics and Metabolite. The concepts of his Glutathione study are interwoven with issues in Microsome, Stereochemistry and Metabolism.
His main research concerns Liver injury, Acetaminophen, Pharmacology, Immunology and Interleukin. His research in Liver injury intersects with topics in ALDH2, Acetylation and Toxicogenomics. His studies deal with areas such as Metabolite, Enzyme, Hepatitis and Heat shock protein as well as Acetaminophen.
His Pharmacology research incorporates elements of Transcription factor, Gene expression, Gene expression profiling and Toxicity. His study in Immunology is interdisciplinary in nature, drawing from both Confounding, Cytotoxic T cell and Drug. His Interleukin study combines topics from a wide range of disciplines, such as Proteome, Cell growth, Drug development and Liver disease, Drug-induced liver disease.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice.
Changqing Ju;Timothy P. Reilly;Mohammed Bourdi;Michael F. Radonovich.
Chemical Research in Toxicology (2002)
Selective Protein Covalent Binding and Target Organ Toxicity
Steven D. Cohen;Neil R. Pumford;Edward A. Khairallah;Kim Boekelheide.
Toxicology and Applied Pharmacology (1997)
Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase.
Mohammed Bourdi;Yasuhiro Masubuchi;Timothy P. Reilly;Hamid R. Amouzadeh.
Hepatology (2002)
Phosgene: a metabolite of chloroform.
Lance R. Pohl;B. Bhooshan;Noel F. Whittaker;Gopal Krishna.
Biochemical and Biophysical Research Communications (1977)
Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.
J G Kenna;H Satoh;D D Christ;L R Pohl.
Journal of Pharmacology and Experimental Therapeutics (1988)
The Immunologic and Metabolic Basis of Drug Hypersensitivities
L R Pohl;H Satoh;D D Christ;J G Kenna.
Annual Review of Pharmacology and Toxicology (1988)
Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
Sijiu Shen;Michael R. Marchick;Margaret R. Davis;George A. Doss.
Chemical Research in Toxicology (1999)
Acetaminophen-induced hepatotoxicity.
Jack A. Hinson;Lance R. Pohl;Terrence J. Monks;James R. Gillette.
Life Sciences (1981)
Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis
Mohammed Bourdi;Weiqiao Chen;Raimund M. Peter;Jackie L. Martin.
Chemical Research in Toxicology (1996)
Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase
H Satoh;B M Martin;A H Schulick;D D Christ.
Proceedings of the National Academy of Sciences of the United States of America (1989)
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