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Biology and Biochemistry

D-Index
79
Citations
21139
World Ranking
4342
National Ranking
2116

Overview

Debra L. Laskin is affiliated with Rutgers, The State University of New Jersey in the United States. Their research spans multiple domains within medicine, agricultural and biological sciences, and veterinary fields.

The primary focus of their work includes the study of pesticide exposure and toxicity, contact dermatitis and allergies, animal testing and alternatives, immunotoxicology and immune responses, air quality and health impacts, heme oxygenase-1 and carbon monoxide, and climate change and health impacts.

Some of the recent papers authored by Debra L. Laskin are:

  • Pulmonary toxicants and fibrosis: innate and adaptive immune mechanisms (2020), Toxicology and Applied Pharmacology
  • Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats (2023), Particle and Fibre Toxicology
  • Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard (2020), Annals of the New York Academy of Sciences
  • DNA damage signaling in the cellular responses to mustard vesicants (2020), Toxicology Letters
  • Regulation of Lung Macrophage Activation and Oxidative Stress Following Ozone Exposure by Farnesoid X Receptor (2020), Toxicological Sciences

Frequent co-authors collaborating with Laskin include:

  • M Cronin
  • A Bryant-Friedrich
  • H. Chon
  • S Crotty
  • J Muldoon

Laskin's publications have appeared mainly in the following venues:

  • Food and Chemical Toxicology (162 publications)
  • Toxicology and Applied Pharmacology (12 publications)
  • The FASEB Journal (10 publications)
  • Toxicological Sciences (8 publications)
  • Annals of the New York Academy of Sciences (5 publications)

Their main fields of study include:

  • Medicine (196 publications)
  • Agricultural and Biological Sciences (154 publications)
  • Veterinary (119 publications)

Subfields of study highlighted in their work include:

  • Plant Science (152 publications)
  • Dermatology (143 publications)
  • Small Animals (119 publications)
  • Immunology (34 publications)
  • Molecular Biology (29 publications)

The breadth of topics covered in their research reflects a consistent interest in toxicological mechanisms, immune system interactions with environmental factors, and the biological responses to chemical exposures.

Best Publications

  • Macrophages and Inflammatory Mediators in Tissue Injury

    Debra Laskin;K. J. Pendino

  • Macrophages and tissue injury: agents of defense or destruction?

    Debra L. Laskin;Vasanthi R. Sunil;Carol R. Gardner;Jeffrey D. Laskin

  • Functional heterogeneity in liver and lung macrophages

    Debra L. Laskin;Barry Weinberger;Jeffrey D. Laskin

  • Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen

    Debra L. Laskin;Carol R. Gardner;Veronica F. Price;David J. Jollow

  • The Toxicology of Inhaled Nitric Oxide

    Barry Weinberger;Debra L. Laskin;Diane E. Heck;Jeffrey D. Laskin

  • Drug-induced liver injury: Mechanisms and test systems

    D. Montgomery Bissell;Gregory J. Gores;Debra L. Laskin;Jay H. Hoofnagle

  • Epidermal growth factor suppresses nitric oxide and hydrogen peroxide production by keratinocytes. Potential role for nitric oxide in the regulation of wound healing.

    D E Heck;D L Laskin;C R Gardner;J D Laskin

  • Macrophages and Inflammatory Mediators in Chemical Toxicity: A Battle of Forces

    Debra L. Laskin

  • Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse

    Donna M. Dambach;Donna M. Dambach;Linda M. Watson;Kevin R. Gray;Stephen K. Durham

  • Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat

    Carol R. Gardner;Diane E. Heck;Chung S. Yang;Paul E. Thomas

  • Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia

    T M Wizemann;C R Gardner;J D Laskin;S Quinones

  • Nitrative and Oxidative Stress in Toxicology and Disease

    Ruth A. Roberts;Debra L. Laskin;Charles V. Smith;Fredika M. Robertson

  • Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells.

    Shiaw-Min Hwang;C. A. Lopez;D. E. Heck;C. R. Gardner

  • Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver.

    Debra L. Laskin;Anne M. Pilaro

  • Oxygen toxicity in premature infants.

    Barry Weinberger;Debra L. Laskin;Diane E. Heck;Jeffrey D. Laskin

  • Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice.

    Lisa A. Morio;Hawjyh Chiu;Karen A. Sprowles;Peihong Zhou

  • Mechanisms Mediating the Vesicant Actions of Sulfur Mustard after Cutaneous Exposure

    Michael P. Shakarjian;Diane E. Heck;Joshua P. Gray;Patrick J. Sinko

  • Nonparenchymal cells and hepatotoxicity.

    Debra L. Laskin

  • Smaller is not always better: nanotechnology yields nanotoxicology.

    Howard M. Kipen;Debra L. Laskin

  • Anti-TNFα therapy in inflammatory lung diseases

    Rama Malaviya;Jeffrey D. Laskin;Debra L. Laskin

Frequent Co-Authors

Jeffrey D. Laskin
Jeffrey D. Laskin Rutgers, The State University of New Jersey
Andrew J. Gow
Andrew J. Gow Rutgers, The State University of New Jersey
Patrick J. Sinko
Patrick J. Sinko Rutgers, The State University of New Jersey
Lauren M. Aleksunes
Lauren M. Aleksunes Rutgers, The State University of New Jersey
Barbara J. Turpin
Barbara J. Turpin University of North Carolina at Chapel Hill
Stanley Stein
Stanley Stein Rutgers, The State University of New Jersey
David T. Denhardt
David T. Denhardt Rutgers, The State University of New Jersey
Shiaw-Min Hwang
Shiaw-Min Hwang Rutgers, The State University of New Jersey
Junfeng Zhang
Junfeng Zhang Duke University
Joachim Kohn
Joachim Kohn Rutgers, The State University of New Jersey

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