World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
120
Citations
50133
World Ranking
641
National Ranking
409

Medicine

D-Index
120
Citations
50562
World Ranking
3767
National Ranking
2070

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Neil Kaplowitz is affiliated with the University of Southern California in the United States. Their research focuses primarily on medicine, with significant contributions to biochemistry, genetics, and molecular biology. A notable aspect of their work includes epidemiology, pharmacology, hepatology, physiology, and molecular biology as key subfields of study.

Kaplowitz's research covers important topics such as liver disease diagnosis and treatment, drug-induced hepatotoxicity and protection, drug transport and resistance mechanisms, diet and metabolism studies, liver disease and transplantation, endoplasmic reticulum stress and disease, and liver diseases and immunity.

They have published extensively in various scientific venues. Frequent publication outlets include:

  • UNC Libraries
  • Hepatology
  • Hepatology Communications
  • Journal of Hepatology
  • Acta Pharmaceutica Sinica B

Recent notable papers authored or coauthored by Kaplowitz include:

  • Endoplasmic reticulum stress in liver diseases (2022, Hepatology)
  • Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry (2021, Journal of Hepatology)
  • Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity (2021, Hepatology)
  • The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice (2021, Acta Pharmaceutica Sinica B)
  • Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism (2023, Cell Host & Microbe)

Kaplowitz frequently collaborates with several coauthors, including Sanda Win, Tin Aung Than, Mercedes Robles-Díaz, Inmaculada Medina-Cáliz, and Aida Ortega-Alonso.

Kaplowitz has been recognized as a Member of the Association of American Physicians, evidencing a level of professional acknowledgment within their field.

Best Publications

  • Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis

    Robert G. Knodell;Kamal G. Ishak;William C. Black;Thomas S. Chen

  • Idiosyncratic drug hepatotoxicity

    Neil Kaplowitz

  • Case definition and phenotype standardization in drug-induced liver injury

    GP Aithal;PB Watkins;RJ Andrade;D Larrey

  • Features and outcomes of 899 patients with drug-induced liver injury: The DILIN prospective study

    Naga Chalasani;Herbert L. Bonkovsky;Robert Fontana;William Lee

  • EASL Clinical Practice Guidelines: Drug-induced liver injury

    Raúl J. Andrade;Guruprasad P. Aithal;Einar S. Björnsson;Neil Kaplowitz

  • The Regulation of Hepatic Glutathione

    N Kaplowitz;T Y Aw;M Ookhtens

  • Aminotransferase Elevations in Healthy Adults Receiving 4 Grams of Acetaminophen Daily: A Randomized Controlled Trial

    Paul B. Watkins;Neil Kaplowitz;John T. Slattery;Connie R. Colonese

  • Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance

    Tom Luedde;Neil Kaplowitz;Robert F. Schwabe

  • Glutathione metabolism and its role in hepatotoxicity.

    Laurie D. DeLeve;Neil Kaplowitz

  • Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

    Cheng Ji;Neil Kaplowitz

  • Drug-Induced Liver Injury

    Neil Kaplowitz

  • Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

    Naoko Hanawa;Mie Shinohara;Behnam Saberi;William A. Gaarde

  • Drug-induced liver injury

    Raul J Andrade;Naga Chalasani;Einar S Björnsson;Ayako Suzuki;Ayako Suzuki

  • c-Jun N-Terminal Kinase Plays a Major Role in Murine Acetaminophen Hepatotoxicity

    Basuki K. Gunawan;Zhang–Xu Liu;Derick Han;Naoko Hanawa

  • Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes.

    C García-Ruiz;A Colell;A Morales;N Kaplowitz

  • Mechanisms of liver cell injury

    Neil Kaplowitz

  • GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect

    J. C. Fernandez-Checa;N. Kaplowitz;C. Garcia-Ruiz;A. Colell

  • Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

    Zhang-Xu Liu;Sugantha Govindarajan;Neil Kaplowitz

  • Drug-Induced Liver Injury

    Gebran Abboud;Neil Kaplowitz

  • Serum alanine aminotransferase in skeletal muscle diseases

    Rahul A. Nathwani;Shireen Pais;Telfer B. Reynolds;Neil Kaplowitz

Frequent Co-Authors

José C. Fernández-Checa
José C. Fernández-Checa University of Southern California
Paul B. Watkins
Paul B. Watkins University of North Carolina at Chapel Hill
Anna Colell
Anna Colell Spanish National Research Council
Berislav V. Zlokovic
Berislav V. Zlokovic University of Southern California
Shelly C. Lu
Shelly C. Lu Cedars-Sinai Medical Center
Albert Morales
Albert Morales Spanish National Research Council
Hidekazu Tsukamoto
Hidekazu Tsukamoto University of Southern California
Manuel Romero-Gómez
Manuel Romero-Gómez University of Seville
David H. Alpers
David H. Alpers Washington University in St. Louis
Dean P. Jones
Dean P. Jones Emory University

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