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Medicine

D-Index
142
Citations
97308
World Ranking
1539
National Ranking
895

Overview

David E. Kleiner is affiliated with the National Institutes of Health in the United States, with a research focus primarily in the field of Medicine. Their work spans several subfields including Epidemiology, Hepatology, Oncology, Pharmacology, and Surgery.

Their research often centers on liver-related conditions and diseases. The main topics of their work include:

  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Drug-Induced Hepatotoxicity and Protection
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Liver Diseases and Immunity
  • Hepatocellular Carcinoma Treatment and Prognosis

David E. Kleiner has published numerous papers in leading journals, with some of the recent notable publications being:

  • MAFLD: A Consensus-Driven Proposed Nomenclature for Metabolic Associated Fatty Liver Disease, 2020, Gastroenterology
  • AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease, 2023, Hepatology
  • Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease, 2021, New England Journal of Medicine
  • SARS-CoV-2 infection and persistence in the human body and brain at autopsy, 2022, Nature
  • SARS-CoV-2 infection of the oral cavity and saliva, 2021, Nature Medicine

The frequent co-authors collaborating with Kleiner include:

  • Theo Heller
  • Christopher Koh
  • Robert J. Fontana
  • Arun J. Sanyal
  • Tim F. Greten

David E. Kleiner has contributed extensively to publications in several prominent research venues. The most frequent publication venues are:

  • Journal of Hepatology
  • UNC Libraries
  • Gastroenterology
  • Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Design and validation of a histological scoring system for nonalcoholic fatty liver disease

    David E. Kleiner;Elizabeth M. Brunt;Mark Van Natta;Cynthia Behling

  • Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

    Arun J. Sanyal;Naga Chalasani;Kris V. Kowdley;Arthur McCullough

  • Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

    Paul Angulo;David E. Kleiner;Sanne Dam-Larsen;Leon A. Adams

  • Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

    Brent A Neuschwander-Tetri;Rohit Loomba;Arun J Sanyal;Joel E Lavine

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    Adrian Ally;Miruna Balasundaram;Rebecca Carlsen;Eric Chuah

  • Randomized Controlled Trial Testing the Effects of Weight Loss on Nonalcoholic Steatohepatitis

    Kittichai Promrat;Kittichai Promrat;David E. Kleiner;Heather M. Niemeier;Heather M. Niemeier;Elizabeth Jackvony

  • Nonalcoholic Fatty Liver Disease (NAFLD) Activity Score and the Histopathologic Diagnosis in NAFLD: Distinct Clinicopathologic Meanings

    Elizabeth M. Brunt;David E. Kleiner;Laura A. Wilson;Patricia Belt

  • Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: The TONIC Randomized Controlled Trial

    Joel E. Lavine;Jeffrey B. Schwimmer;Mark L. Van Natta;Jean P. Molleston;Jean P. Molleston

  • Quantitative zymography: detection of picogram quantities of gelatinases.

    D.E. Kleiner;W.G. Stetlerstevenson

  • Matrix metalloproteinases and metastasis.

    David E. Kleiner;William G. Stetler-Stevenson

  • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis.

    Kittichai Promrat;Glen Lutchman;Gabriel I. Uwaifo;Renee J. Freedman

  • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4

    Kimberly E. Beck;Joseph A. Blansfield;Khoi Q. Tran;Andrew L. Feldman

  • Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

    Hye Sun Kuehn;Weiming Ouyang;Bernice Lo;Elissa K. Deenick;Elissa K. Deenick

  • Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

    Qing Zhou;Dan Yang;Amanda K Ombrello;Andrey V Zavialov

  • Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma.

    Austin G. Duffy;Susanna V. Ulahannan;Oxana Makorova-Rusher;Osama Rahma

  • Endpoints and clinical trial design for nonalcoholic steatohepatitis.

    Arun J. Sanyal;Elizabeth M. Brunt;David E. Kleiner;Kris V. Kowdley

  • Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis.

    William G. Stetler-Stevenson;Lance A. Liotta;David E. Kleiner

  • SARS-CoV-2 infection of the oral cavity and saliva.

    Ni Huang;Paola Pérez;Takafumi Kato;Yu Mikami

  • Hepatic failure and lactic acidosis due to fialuridine (fiau), an investigational nucleoside analogue for chronic hepatitis b

    Robin Mckenzie;Michael W. Fried;Richard Sallie;Hari Conjeevaram

  • Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease.

    Arun J. Sanyal;Mark L. van Natta;Jeanne Clark;Brent A. Neuschwander-Tetri

Frequent Co-Authors

Theo Heller
Theo Heller National Institutes of Health
Jay H. Hoofnagle
Jay H. Hoofnagle National Institutes of Health
Naga Chalasani
Naga Chalasani Indiana University
Marc G. Ghany
Marc G. Ghany National Institutes of Health
Elizabeth M. Brunt
Elizabeth M. Brunt Washington University in St. Louis
Robert J. Fontana
Robert J. Fontana University of Michigan–Ann Arbor
Rohit Loomba
Rohit Loomba University of California, San Diego
Brent A. Neuschwander-Tetri
Brent A. Neuschwander-Tetri Saint Louis University
Allan D. Kirk
Allan D. Kirk Duke University
T. Jake Liang
T. Jake Liang National Institutes of Health

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