World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
102
Citations
35414
World Ranking
375
National Ranking
172

Medicine

D-Index
102
Citations
35771
World Ranking
7709
National Ranking
4008

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

T. Jake Liang is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on medicine, with significant contributions across subfields such as epidemiology, hepatology, infectious diseases, molecular biology, and plant science.

The scientist's main topics of research include:

  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • COVID-19 Clinical Research Studies

Their frequently published papers cover various aspects of viral infections and liver diseases. Notable publications include:

  • "Is SARS-CoV-2 Also an Enteric Pathogen With Potential Fecal-Oral Transmission? A COVID-19 Virological and Clinical Review," 2020, Gastroenterology
  • "Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection," 2021, New England Journal of Medicine
  • "A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma," 2020, Cell
  • "Modeling PNPLA3-Associated NAFLD Using Human-Induced Pluripotent Stem Cells," 2021, Hepatology
  • "Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection," 2020, Journal of Clinical Investigation

Collaborations are a key aspect of their work, with frequent co-authors being Seung Bum Park, Zongyi Hu, Marc G. Ghany, Madeleine Leek, and Jordan J. Feld.

Their research has appeared repeatedly in high-impact journals such as Clinical Infectious Diseases, Journal of Hepatology, New England Journal of Medicine, Hepatology, and JCI Insight.

In recognition of their professional contributions, T. Jake Liang was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

  • Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

    Takaji Wakita;Thomas Pietschmann;Takanobu Kato;Takanobu Kato;Tomoko Date

  • Hepatitis B: the virus and disease.

    T. Jake Liang

  • Management of Hepatitis B: Summary of a Clinical Research Workshop

    Jay H. Hoofnagle;Edward Doo;T. Jake Liang;Russell Fleischer

  • Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

    Julie Lucifora;Yuchen Xia;Florian Reisinger;Ke Zhang

  • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis.

    Kittichai Promrat;Glen Lutchman;Gabriel I. Uwaifo;Renee J. Freedman

  • Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection

    Heiner Wedemeyer;Xiao Song He;Michelina Nascimbeni;Anthony R. Davis

  • Hepatitis B Reactivation Associated With Immune Suppressive and Biological Modifier Therapies: Current Concepts, Management Strategies, and Future Directions.

    Rohit Loomba;T. Jake Liang

  • Systematic review: the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy.

    Rohit Loomba;Ayana Rowley;Robert Wesley;T. Jake Liang

  • Current and future therapies for hepatitis C virus infection.

    T. Jake Liang;Marc G. Ghany

  • A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

    T. Jake Liang;Kiyoshi Hasegawa;Nurit Rimon;Jack R. Wands

  • Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection

    David Milich;T. Jake Liang

  • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease†

    Yaron Rotman;Christopher Koh;Joseph M. Zmuda;David E. Kleiner

  • Long‐term therapy of chronic hepatitis B with lamivudine

    Daryl T.-Y. Lau;M. Farooq Khokhar;Edward Doo;Marc G. Ghany

  • Progression of fibrosis in chronic hepatitis C

    Marc G. Ghany;David E. Kleiner;Harvey Alter;Edward Doo

  • Hepatitis C Virus Structural Proteins Assemble into Viruslike Particles in Insect Cells

    Thomas F. Baumert;Susumu Ito;David T. Wong;T. Jake Liang

  • A global scientific strategy to cure hepatitis B

    Peter A Revill;Francis V Chisari;Joan M Block;Maura Dandri

  • A genome-wide genetic screen for host factors required for hepatitis C virus propagation

    Qisheng Li;Abraham L. Brass;Aylwin Ng;Zongyi Hu

  • Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

    Johnson Y. N. Lau;Robert C. Tam;T. Jake Liang;Zhi Hong

  • Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection

    Netanya G. Sandler;Christopher Koh;Annelys Roque;Jason L. Eccleston

  • Management of antiviral resistance in patients with chronic hepatitis B.

    Stephen Locarnini;Angelas Hatzakis;Jenny Heathcote;Emmet B. Keeffe

  • Management of hepatitis B: Summary of a clinical research workshop Potential conflict of interest: Dr. Lok is a consultant and received grants from GlaxoSmithKline, Bristol-Myers Squibb, Idenix, Gilead, Roche, and Innogenetics.

    Jay H. Hoofnagle;Edward Doo;T. Jake Liang;Russell Fleischer

Frequent Co-Authors

Marc G. Ghany
Marc G. Ghany National Institutes of Health
Jay H. Hoofnagle
Jay H. Hoofnagle National Institutes of Health
Theo Heller
Theo Heller National Institutes of Health
David E. Kleiner
David E. Kleiner National Institutes of Health
Barbara Rehermann
Barbara Rehermann National Institute of Diabetes and Digestive and Kidney Diseases
Harvey J. Alter
Harvey J. Alter National Institutes of Health
Rohit Loomba
Rohit Loomba University of California, San Diego
Takaji Wakita
Takaji Wakita National Institute of Infectious Diseases
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg

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