Her scientific interests lie mostly in Methyltransferase, Gene, Genetics, Biochemistry and Cancer research. Her studies in Methyltransferase integrate themes in fields like Histone H3 and Epigenetics. When carried out as part of a general Genetics research project, her work on DNA Methylation Regulation, RNA-Directed DNA Methylation, Epigenomics and Epigenetics of physical exercise is frequently linked to work in Histone code, therefore connecting diverse disciplines of study.
Her research on Biochemistry frequently connects to adjacent areas such as Cell biology. Her Cancer research research is multidisciplinary, incorporating elements of Carcinogenesis, Chromatin, Histone and MYST3. Her Histone research incorporates elements of Acetylation, Human genome and Methyltransferase complex.
Dalia Barsyte-Lovejoy mainly focuses on Methyltransferase, Biochemistry, Cell biology, Histone and Epigenetics. Her Methyltransferase study is concerned with the field of Methylation as a whole. Her research integrates issues of Teneurin, Protein domain, Transcription factor and Messenger RNA in her study of Cell biology.
Her work carried out in the field of Histone brings together such families of science as Chromatin and Function. Her Epigenetics study combines topics in areas such as Chemical biology, Epigenomics, DNA methylation and Cellular differentiation. Her Gene study deals with the bigger picture of Genetics.
Dalia Barsyte-Lovejoy mostly deals with Cell biology, Methyltransferase, Histone, Methylation and Arginine. Her study in Cell biology is interdisciplinary in nature, drawing from both Chromatin, Protein domain, Gene and Binding domain. Her study with Methyltransferase involves better knowledge in Biochemistry.
Her research in Histone focuses on subjects like Transcription factor, which are connected to DNA methylation, Gene expression and Acetylation. The concepts of her Methylation study are interwoven with issues in Cancer, Epigenetics and Computational biology. Her Epigenetics research incorporates themes from Epigenomics and Drug discovery.
Her primary areas of investigation include Cell biology, Methylation, Methyltransferase, Epigenetics and Arginine. Her biological study deals with issues like Chromatin, which deal with fields such as In vitro, Protein domain, Myeloid leukemia and Messenger RNA. Her Methyltransferase study is related to the wider topic of Biochemistry.
Dalia Barsyte-Lovejoy has researched Epigenetics in several fields, including Chemical biology, Histone and Computational biology. Her work on EZH2 as part of general Histone study is frequently linked to Differentiation therapy, therefore connecting diverse disciplines of science. Her research integrates issues of Cell, Proteostasis and Proteasome in her study of Arginine.
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Histone recognition and large-scale structural analysis of the human bromodomain family.
Panagis Filippakopoulos;Sarah Picaud;Maria Mangos;Tracy Keates.
Cell (2012)
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
Masoud Vedadi;Dalia Barsyte-Lovejoy;Feng Liu;Sylvie Rival-Gervier.
Nature Chemical Biology (2011)
The c-Myc Oncogene Directly Induces the H19 Noncoding RNA by Allele-Specific Binding to Potentiate Tumorigenesis
Dalia Barsyte-Lovejoy;Suzanne K. Lau;Paul C. Boutros;Fereshteh Khosravi.
Cancer Research (2006)
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1.
Kyle D. Konze;Anqi Ma;Fengling Li;Dalia Barsyte-Lovejoy.
ACS Chemical Biology (2013)
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
Jiajun Zhu;Morgan A. Sammons;Greg Donahue;Zhixun Dou.
Nature (2015)
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation
Scott B Rothbart;Krzysztof Krajewski;Nataliya Nady;Wolfram Tempel.
Nature Structural & Molecular Biology (2012)
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors
Wenyu Yu;Emma J. Chory;Emma J. Chory;Amy K. Wernimont;Wolfram Tempel.
Nature Communications (2012)
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression.
Daniel Y.L. Mao;Daniel Y.L. Mao;John D. Watson;Pearlly S. Yan;Dalia Barsyte-Lovejoy;Dalia Barsyte-Lovejoy.
Current Biology (2003)
Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.
Feng Liu;Dalia Barsyte-Lovejoy;Fengling Li;Yan Xiong.
Journal of Medicinal Chemistry (2013)
Cancer therapeutics: targeting the dark side of Myc.
Romina Ponzielli;Sigal Katz;Dalia Barsyte-Lovejoy;Linda Z. Penn.
European Journal of Cancer (2005)
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