What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Biochemistry, Cancer research, Methyltransferase, Signal transduction and Histone H3.
His Cancer research research includes themes of Haematopoiesis, Leukemia, Immunology, Kinase and Genomic imprinting.
His research investigates the connection between Methyltransferase and topics such as Transferase that intersect with issues in Arginine and Chromatin remodeling.
His Signal transduction study which covers Receptor that intersects with Neuroscience and Optogenetics.
Jian Jin combines subjects such as EZH2 and Gene knockdown with his study of Histone H3.
Jian Jin has included themes like Stereochemistry and Small molecule in his Structure–activity relationship study.
His most cited work include:
- Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer (509 citations)
- The promise and peril of chemical probes. (443 citations)
- A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells (375 citations)
What are the main themes of his work throughout his whole career to date?
Jian Jin focuses on Biochemistry, Cancer research, Methyltransferase, Epigenetics and Pharmacology.
His study in Structure–activity relationship, Lysine, Small molecule, Enzyme and Drug discovery is carried out as part of his studies in Biochemistry.
Jian Jin focuses mostly in the field of Cancer research, narrowing it down to matters related to EZH2 and, in some cases, Multiple myeloma and Histone H3.
The various areas that Jian Jin examines in his Methyltransferase study include Arginine, Stereochemistry and Transferase.
His Epigenetics research is multidisciplinary, incorporating perspectives in Histone, Cellular differentiation and Cell biology.
His Pharmacology study integrates concerns from other disciplines, such as Agonist, Receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor and In vivo.
He most often published in these fields:
- Biochemistry (21.76%)
- Cancer research (19.08%)
- Methyltransferase (15.65%)
What were the highlights of his more recent work (between 2018-2021)?
- Cancer research (19.08%)
- Cell biology (11.83%)
- Epigenetics (14.50%)
In recent papers he was focusing on the following fields of study:
Jian Jin spends much of his time researching Cancer research, Cell biology, Epigenetics, Methylation and Methyltransferase.
His work deals with themes such as Cancer, Cell culture, EZH2, Cyclin-dependent kinase 6 and Multiple myeloma, which intersect with Cancer research.
His Cell biology research also works with subjects such as
- Regulation of gene expression, Carcinogenesis and Small molecule most often made with reference to Chromatin,
- Ubiquitin ligase which connect with Proteolysis, In vivo and Kinase,
- Gene which connect with Neuroblastoma,
- Acetylation that connect with fields like Tyrosine phosphorylation.
He interconnects Wnt signaling pathway, Epigenomics, Downregulation and upregulation and Cellular differentiation in the investigation of issues within Epigenetics.
His research integrates issues of RNA Splicing Factors, RNA splicing, Histone and Leukemia in his study of Methylation.
Biochemistry and DNA are closely tied to his Methyltransferase research.
Between 2018 and 2021, his most popular works were:
- Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation. (64 citations)
- A chemical biology toolbox to study protein methyltransferases and epigenetic signaling (60 citations)
- Light-induced control of protein destruction by opto-PROTAC. (32 citations)
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