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Immunology

D-Index
69
Citations
20882
World Ranking
2483
National Ranking
213

Overview

David C. Wraith is affiliated with the University of Birmingham in the United Kingdom. Their research primarily focuses on medicine and immunology and microbiology, with significant attention to subfields including immunology, infectious diseases, neurology, oncology, and radiology, nuclear medicine, and imaging.

Their work covers main topics such as T-cell and B-cell immunology, COVID-19 clinical research studies, long-term effects of COVID-19, immune cell function and interaction, SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, and monoclonal and polyclonal antibodies research.

David C. Wraith regularly publishes in several scientific venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Nature Medicine, Cell Reports, and Clinical & Experimental Immunology.

Recent published papers include:

  • Symptoms and risk factors for long COVID in non-hospitalized adults, 2022, Nature Medicine
  • SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study, 2020, Thorax
  • Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration, 2020, Cell Reports
  • Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection, 2021, Clinical & Experimental Immunology

Frequent co-authors working alongside David C. Wraith include Adrian Shields, Sian Faustini, Adam F. Cunningham, Mark T. Drayson, and Alex Richter.

Best Publications

  • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

    A.R.M. Townsend;J. Rothbard;F.M. Gotch;G. Bahadur

  • Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

    Hans Acha-Orbea;Dennis J. Mitchell;Luika Timmermann;David C. Wraith

  • IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells

    Pedro L. Vieira;Jillian R. Christensen;Sophie Minaee;Emma J. O’Neill

  • Low avidity recognition of self-antigen by T cells permits escape from central tolerance

    George Y. Liu;Paul J. Fairchild;Richard M. Smith;John R. Prowle

  • Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy.

    David C. Wraith;Dawn E. Smilek;Dennis J. Mitchell;Lawrence Steinman

  • Regulation of adaptive immunity; the role of interleukin-10

    T. H. Sky Ng;Graham J. Britton;Elaine V. Hill;Johan Verhagen

  • Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

    Brocke S;Gijbels K;Allegretta M;Ferber I

  • Vaccination and autoimmune disease: what is the evidence?

    David C Wraith;Michel Goldman;Paul-Henri Lambert

  • Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

    Richard A. O'Connor;Catriona T. Prendergast;Catherine A. Sabatos;Clement W. Z. Lau

  • Peptide-based therapeutic vaccines for allergic and autoimmune diseases.

    Mark Larché;David C Wraith

  • Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice.

    Gerard F. Hoyne;Robyn E. O’hehir;David C. Wraith;Wayne R. Thomas

  • Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo

    Anette Sundstedt;Emma J. O’Neill;Kirsty S. Nicolson;David C. Wraith

  • Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

    Barbara Metzler;David C. Wraith

  • A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis.

    Dawn E. Smilek;David C. Wraith;Suzanne Hodgkinson;Sunita Dwivedy

  • Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis

    Madhav Kishore;Kenneth C.P. Cheung;Hongmei Fu;Fabrizia Bonacina

  • Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

    Bénédicte Manoury;Daniela Mazzeo;Lars Fugger;Nick Viner

  • SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.

    Adrian Shields;Adrian Shields;Sian E Faustini;Marisol Perez-Toledo;Sian Jossi

  • T cell recognition as the target for immune intervention in autoimmune disease

    David C. Wraith;Hugh O. McDevitt;Lawrence Steinman;Hans Acha-Orbea

  • TGF-β-dependent Induction of CD4⁺CD25⁺Foxp3⁺ Tregs by Liver Sinusoidal Endothelial Cells

    Antonella Carambia;Barbara Freund;Dorothee Schwinge;Markus Heine

  • Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10

    Christoph Burkhart;George Y. Liu;Stephen M. Anderton;Barbara Metzler

  • Selection and fine-tuning of the autoimmune T-cell repertoire

    Stephen M. Anderton;David C. Wraith

  • T-helper 1 cells facilitate the entry of T-helper 17 cells to the central nervous system during experimental autoimmune encephalomyelitis

    RA O'Connor;CT Prendergast;CA Sabatos;Cwz Lau

Frequent Co-Authors

Stephen M. Anderton
Stephen M. Anderton University of Edinburgh
George Y. Liu
George Y. Liu University of California, San Diego
Christopher J. Elson
Christopher J. Elson University of Bristol
Ansgar W. Lohse
Ansgar W. Lohse Universität Hamburg
Li Li
Li Li University of Queensland
Irun R. Cohen
Irun R. Cohen Weizmann Institute of Science
Lawrence Steinman
Lawrence Steinman Stanford University
Anne O'Garra
Anne O'Garra The Francis Crick Institute
Richard R. Meehan
Richard R. Meehan University of Edinburgh
Michael J. Day
Michael J. Day Murdoch University

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