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Microbiology

D-Index
41
Citations
9000
World Ranking
5414
National Ranking
2045

Overview

George Y. Liu is affiliated with the University of California, San Diego in the United States. Their research spans medicine, biochemistry, genetics, molecular biology, immunology, and microbiology, with a focus on infectious diseases, molecular biology, immunology, epidemiology, and dermatology.

The scientist's work primarily addresses topics such as antimicrobial resistance in Staphylococcus, immune response and inflammation, bacterial biofilms and quorum sensing, bacterial identification and susceptibility testing, photodynamic therapy research studies, nanoplatforms for cancer theranostics, and antimicrobial peptides and activities.

Recent publications include:

  • Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures (2020, Cell)
  • Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine (2022, Cell Host & Microbe)
  • Photo-Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA (2020, Advanced Science)
  • Use of Metagenomic Next-Generation Sequencing to Identify Pathogens in Pediatric Osteoarticular Infections (2021, Open Forum Infectious Diseases)
  • Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells (2022, JCI Insight)

Frequent collaborators include:

  • Chih-Ming Tsai
  • Victor Nizet
  • J.R. Caldera
  • Irshad A. Hajam
  • Cesia Gonzalez

Their publications appear most often in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Advanced Science
  • Cell Reports Medicine
  • Nature Communications
  • Cell

Best Publications

  • Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

    George Y. Liu;Anthony Essex;John T. Buchanan;Vivekanand Datta

  • DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps.

    John T. Buchanan;Amelia J. Simpson;Ramy K. Aziz;George Y. Liu

  • IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

    Toby Lawrence;Toby Lawrence;Magali Bebien;George Y. Liu;Victor Nizet

  • A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence

    Chia I. Liu;Chia I. Liu;George Y. Liu;Yongcheng Song;Fenglin Yin

  • Low avidity recognition of self-antigen by T cells permits escape from central tolerance

    George Y. Liu;Paul J. Fairchild;Richard M. Smith;John R. Prowle

  • Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury

    Binh An Diep;Liana Chan;Pierre Tattevin;Osamu Kajikawa

  • Color me bad: microbial pigments as virulence factors

    George Y. Liu;Victor Nizet

  • Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

    Takahiro Shimada;Bong Goo Park;Andrea J. Wolf;Constantinos Brikos

  • Group B streptococcal β-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis

    Kelly S. Doran;George Y. Liu;Victor Nizet

  • Sword and shield: Linked group B streptococcal β-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense

    George Y. Liu;Kelly S. Doran;Toby Lawrence;Nicole Turkson

  • Carotenoid-Related Alteration of Cell Membrane Fluidity Impacts Staphylococcus aureus Susceptibility to Host Defense Peptides

    Nagendra N. Mishra;George Y. Liu;George Y. Liu;Michael R. Yeaman;Cynthia C. Nast;Cynthia C. Nast

  • MOLECULAR PATHOGENESIS OF STAPHYLOCOCCUS AUREUS INFECTION

    George Y Liu

  • Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10

    Christoph Burkhart;George Y. Liu;Stephen M. Anderton;Barbara Metzler

  • Vitamin D Induces Innate Antibacterial Responses in Human Trophoblasts via an Intracrine Pathway

    N. Liu;A.T. Kaplan;J. Low;L. Nguyen

  • Increased free cholesterol in plasma low and very low density lipoproteins in non-insulin-dependent diabetes mellitus: its role in the inhibition of cholesteryl ester transfer.

    Christopher J. Fielding;Gerald M. Reaven;George Liu;Phoebe E. Fielding

  • A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence

    Heather C. Maisey;Darin Quach;Mary E. Hensler;George Y. Liu

  • Staphylococcus aureus Panton-Valentine Leukocidin Contributes to Inflammation and Muscle Tissue Injury

    Ching Wen Tseng;Ching Wen Tseng;Pierre Kyme;Pierre Kyme;Jennifer E Low;Jennifer E Low;Miguel A. Rocha;Miguel A. Rocha

  • Isolation and characterization of antimicrobial compounds in plant extracts against multidrug-resistant Acinetobacter baumannii.

    Yoko Miyasaki;John D. Rabenstein;Joshua Rhea;Marie-Laure Crouch

  • Survival and transmission of community-associated methicillin-resistant Staphylococcus aureus from fomites

    Rishi Desai;Pia S. Pannaraj;Pia S. Pannaraj;Jaclyn Agopian;Catherine A. Sugar

  • Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures.

    Jacob M. Wozniak;Robert H. Mills;Joshua Olson;Joshua Olson;J.R. Caldera;J.R. Caldera

  • Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae.

    Bonggoo Park;Victor Nizet;George Y. Liu

  • Affinity for class II MHC determines the extent to which soluble peptides tolerize autoreactive T cells in naive and primed adult mice—implications for autoimmunity

    George Y. Liu;David C. Wraith

  • Inhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus: In Vitro, in Vivo, and Crystallographic Results†

    Yongcheng Song;Chia-I Liu;Fu-Yang Lin;Joo Hwan No

  • Innate Immune Dysfunctions in Aged Mice Facilitate the Systemic Dissemination of Methicillin-Resistant S. aureus

    Ching Wen Tseng;Ching Wen Tseng;Pierre A. Kyme;Pierre A. Kyme;Andrea Arruda;Andrea Arruda;V. Krishnan Ramanujan

Frequent Co-Authors

Victor Nizet
Victor Nizet University of California, San Diego
David M. Underhill
David M. Underhill Cedars-Sinai Medical Center
Moshe Arditi
Moshe Arditi Cedars-Sinai Medical Center
Ji-Xin Cheng
Ji-Xin Cheng Boston University
David C. Wraith
David C. Wraith University of Birmingham
H. Phillip Koeffler
H. Phillip Koeffler Cedars-Sinai Medical Center
Kelly S. Doran
Kelly S. Doran University of Colorado Denver
Toby Lawrence
Toby Lawrence King's College London
Loren G. Miller
Loren G. Miller UCLA Medical Center
Mohamed N. Seleem
Mohamed N. Seleem Virginia Tech

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