Neuroscience, Hippocampus, Alzheimer's disease, Human brain and Neuron are his primary areas of study. His Neuroscience study incorporates themes from Epigenetic regulation of neurogenesis, DNA methylation and Epigenetics. His Hippocampus study combines topics in areas such as Hippocampal formation, Forebrain, Physiology and Pathology.
His Alzheimer's disease research integrates issues from Epigenesis, Senescence and Degenerative disease. His Senescence research is multidisciplinary, incorporating elements of Dendritic spine and Dendrite. His study focuses on the intersection of Neuron and fields such as Aging brain with connections in the field of Regulation of gene expression, Innate immune system, Immune system and Immunology.
Paul D. Coleman focuses on Neuroscience, Disease, Alzheimer's disease, Hippocampus and Pathology. The Disease study combines topics in areas such as Transcriptome, Cytoskeleton, DNA methylation and Bioinformatics. His work deals with themes such as Genetics, Gap-43 protein, Epigenetics and Degenerative disease, which intersect with Alzheimer's disease.
In his research on the topic of Hippocampus, Antisense RNA is strongly related with Cell. Paul D. Coleman combines subjects such as Hippocampal formation and Human brain with his study of Pathology. His work in Neuron addresses subjects such as Senescence, which are connected to disciplines such as Endocrinology.
The scientist’s investigation covers issues in Neuroscience, Hippocampus, Disease, Epigenetics and DNA methylation. Paul D. Coleman integrates Neuroscience with Orexin receptor in his study. His Hippocampus research focuses on Cell and how it relates to Orders of magnitude, Cell biology, Neurotransmitter receptor and Neuron.
His Disease research includes themes of Bioinformatics, Transcriptome, Real-time polymerase chain reaction, Computational biology and Family history. His Epigenetics research incorporates elements of Candidate gene, Pathogenesis, BACE1-AS, Alzheimer's disease and Gene regulatory network. Paul D. Coleman has researched Alzheimer's disease in several fields, including Cell nucleus, Amyloid beta, Intracellular and Histone.
Paul D. Coleman mostly deals with Neuroscience, Epigenetics, Hippocampus, Microglia and Internal medicine. His Neuroscience research is multidisciplinary, incorporating perspectives in Alzheimer's disease, BACE1-AS and Cell, Genetics. The concepts of his Alzheimer's disease study are interwoven with issues in Cell nucleus, Gene expression, Intracellular and Histone.
His Epigenetics research also works with subjects such as
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Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
M.J West;P.D Coleman;D.G Flood;J.C Troncoso.
The Lancet (1994)
Analysis of gene expression in single live neurons.
James Eberwine;Hermes Yeh;Kevin Miyashiro;Yanxiang Cao.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Neuron numbers and dendritic extent in normal aging and Alzheimer's disease
Paul D. Coleman;Dorothy G. Flood.
Neurobiology of Aging (1987)
Dendritic growth in the aged human brain and failure of growth in senile dementia
Stephen J. Buell;Paul D. Coleman.
Gene expression changes in the course of normal brain aging are sexually dimorphic.
Nicole C. Berchtold;David H. Cribbs;Paul D. Coleman;Joseph Rogers.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Neurons May Live for Decades with Neurofibrillary Tangles
Renee Morsch;William Simon;Paul D. Coleman.
Journal of Neuropathology and Experimental Neurology (1999)
Synaptic slaughter in Alzheimer’s disease
Paul D. Coleman;Pamela J. Yao.
Neurobiology of Aging (2003)
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
David H Cribbs;Nicole C Berchtold;Victoria Perreau;Paul D Coleman.
Journal of Neuroinflammation (2012)
Epigenetic changes in Alzheimer's disease: decrements in DNA methylation
Diego Mastroeni;Andrew Grover;Elaine Delvaux;Charisse Whiteside.
Neurobiology of Aging (2010)
A focus on the synapse for neuroprotection in Alzheimer disease and other dementias
Paul Coleman;Howard Federoff;Roger Kurlan.
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