D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 81 Citations 22,132 276 World Ranking 886 National Ranking 481

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

2012 - Fellow, National Academy of Inventors

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Howard J. Federoff spends much of his time researching Neuroscience, Cell biology, Programmed cell death, Substantia nigra and Internal medicine. Howard J. Federoff has included themes like Neurotrophic factors and Neurite in his Neuroscience study. The concepts of his Cell biology study are interwoven with issues in Microglia, Excitotoxicity, Molecular biology, Apoptosis-inducing factor and Proinflammatory cytokine.

His work deals with themes such as Gene expression, Transgene, Ischemia and Neuroprotection, which intersect with Programmed cell death. His studies deal with areas such as Glial cell line-derived neurotrophic factor and Putamen as well as Substantia nigra. He studied Internal medicine and Endocrinology that intersect with Nerve growth factor.

His most cited work include:

  • Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. (1511 citations)
  • Plasma phospholipids identify antecedent memory impairment in older adults (655 citations)
  • PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease (569 citations)

What are the main themes of his work throughout his whole career to date?

Howard J. Federoff focuses on Virology, Molecular biology, Disease, Herpes simplex virus and Neuroscience. His Virology study combines topics in areas such as Genetic enhancement and Immune system. His research integrates issues of Gene expression and Transgene in his study of Molecular biology.

As part of the same scientific family, Howard J. Federoff usually focuses on Disease, concentrating on Immunology and intersecting with Cell biology, Genetically modified mouse and Amyloid. His Cell biology study integrates concerns from other disciplines, such as Programmed cell death and Nerve growth factor. His Herpes simplex virus research is multidisciplinary, incorporating perspectives in Cell culture, Oncolytic virus and In vivo.

He most often published in these fields:

  • Virology (18.90%)
  • Molecular biology (18.64%)
  • Disease (16.27%)

What were the highlights of his more recent work (between 2012-2020)?

  • Disease (16.27%)
  • Bioinformatics (8.14%)
  • Internal medicine (10.24%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Disease, Bioinformatics, Internal medicine, Parkinson's disease and Memory impairment. His Disease research incorporates themes from Microvesicles, Immunology, Biomarker, Pharmacology and Cohort. His biological study spans a wide range of topics, including Genetic enhancement and Neurodegeneration.

He interconnects Endocrinology and Oncology in the investigation of issues within Internal medicine. Many of his research projects under Parkinson's disease are closely connected to Genome-wide association study with Genome-wide association study, tying the diverse disciplines of science together. His Substantia nigra study integrates concerns from other disciplines, such as Neuroinflammation, Microglia and Alpha-synuclein.

Between 2012 and 2020, his most popular works were:

  • Plasma phospholipids identify antecedent memory impairment in older adults (655 citations)
  • Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study (390 citations)
  • Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study (131 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His main research concerns Disease, Parkinson's disease, Bioinformatics, Internal medicine and Substantia nigra. His Disease research is mostly focused on the topic Alzheimer's disease. His study on Parkinson's disease also encompasses disciplines like

  • Glial cell line-derived neurotrophic factor that connect with fields like Tolerability, Neurotrophin and Toxicity,
  • Inflammation which connect with Etiology, Neuropathology, Immune system, Peripheral and Cell biology.

In his research, Apolipoprotein E is intimately related to Oncology, which falls under the overarching field of Internal medicine. His Substantia nigra study introduces a deeper knowledge of Dopamine. His Microglia study frequently draws connections between related disciplines such as Neuroscience.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.

Seong Woon Yu;Hongmin Wang;Marc F. Poitras;Carmen Coombs.
Science (2002)

2166 Citations

Plasma phospholipids identify antecedent memory impairment in older adults

Mark Mapstone;Amrita K Cheema;Massimo S Fiandaca;Xiaogang Zhong.
Nature Medicine (2014)

946 Citations

PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

Bin Zheng;Zhixiang Liao;Joseph J. Locascio;Kristen A. Lesniak.
Science Translational Medicine (2010)

770 Citations

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

Massimo S. Fiandaca;Dimitrios Kapogiannis;Mark Mapstone;Adam Boxer.
Alzheimers & Dementia (2015)

607 Citations

Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss.

A.I Brooks;C.A Chadwick;H.A Gelbard;D.A Cory-Slechta.
Brain Research (1999)

556 Citations

Regulation of neuronal traits by a novel transcriptional complex.

Nurit Ballas;Elena Battaglioli;Fouad Atouf;Maria E. Andres.
Neuron (2001)

489 Citations

Synuclein activates microglia in a model of Parkinson’s Disease

Xiaomin Su;Kathleen A. Maguire-Zeiss;Rita Giuliano;Landa Prifti.
Neurobiology of Aging (2008)

464 Citations

Expression of bcl-2 From a Defective Herpes Simplex Virus–1 Vector Limits Neuronal Death in Focal Cerebral Ischemia

Matthew D. Linnik;Peter Zahos;Michael D. Geschwind;Howard J. Federoff.
Stroke (1995)

435 Citations

Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons.

Laurie J. Goodman;Janet Valverde;Filip Lim;Michael D. Geschwind.
Molecular and Cellular Neuroscience (1996)

414 Citations

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

Byoung Dae Lee;Joo Ho Shin;Jackalina Vankampen;Leonard Petrucelli.
Nature Medicine (2010)

393 Citations

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