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Biology and Biochemistry

D-Index
55
Citations
31377
World Ranking
14730
National Ranking
1161

Overview

Toby Lawrence is affiliated with King's College London in the United Kingdom. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine, with a considerable focus on Immunology, Oncology, and Molecular Biology. Subfields also include Neurology and Pulmonary and Respiratory Medicine. Their work encompasses various main topics such as Immunotherapy and Immune Responses, Immune cells in cancer, T-cell and B-cell Immunology, Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, Immune Response and Inflammation, and Atherosclerosis and Cardiovascular Diseases.

Lawrence has contributed to a number of scientific publications, with recent papers including:

  • "Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer" (2020) published in The Journal of Experimental Medicine
  • "NF-κB-dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity" (2021) published in Science Immunology
  • "The Role of Plasmacytoid Dendritic Cells in Cancers" (2021) published in Frontiers in Immunology
  • "Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression" (2021) published in Science Advances
  • "Meningeal macrophages protect against viral neuroinfection" (2022) published in Immunity

The researcher frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, BMC Biology, eLife, and SSRN Electronic Journal.

Frequent collaborators include Yinming Liang, Binhui Zhou, Liaoxun Lu, Lichen Zhang, and James W. Opzoomer.

Best Publications

  • Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

    Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher

  • Transcriptional regulation of macrophage polarization: enabling diversity with identity.

    Toby Lawrence;Gioacchino Natoli

  • Innate immunity gone awry : linking microbial infections to chronic inflammation and cancer

    Michael Karin;Toby Lawrence;Victor Nizet

  • Anti-inflammatory lipid mediators and insights into the resolution of inflammation

    Toby Lawrence;Toby Lawrence;Derek A. Willoughby;Derek W. Gilroy

  • Possible new role for NF-kappaB in the resolution of inflammation.

    Toby Lawrence;Derek W. Gilroy;Paul R. Colville-Nash;Derek A. Willoughby

  • “Re-educating” tumor-associated macrophages by targeting NF-κB

    Thorsten Hagemann;Toby Lawrence;Iain McNeish;Kellie A. Charles

  • Granulocyte-Macrophage Colony-Stimulating Factor (CSF) and Macrophage CSF-Dependent Macrophage Phenotypes Display Differences in Cytokine Profiles and Transcription Factor Activities: Implications for CSF Blockade in Inflammation

    Andrew J. Fleetwood;Toby Lawrence;John A. Hamilton;Andrew D. Cook

  • Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

    Marc Dalod;Rabie Chelbi;Bernard Malissen;Toby Lawrence

  • Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

    Arnaud Didierlaurent;John Goulding;Seema Patel;Robert Snelgrove

  • Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

    Sonya M. Abraham;Toby Lawrence;Anna Kleiman;Paul Warden

  • Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

    Pieter Goossens;Pieter Goossens;Juan Rodriguez-Vita;Juan Rodriguez-Vita;Anders Etzerodt;Anders Etzerodt;Marion Masse

  • Chronic inflammation: a failure of resolution?

    Toby Lawrence;Derek W. Gilroy

  • The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans

    Kellie A. Charles;Hagen Kulbe;Robin Soper;Monica Escorcio-Correia

  • The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression.

    Chun Kim;Yasuyo Sano;Kristina Todorova;Bradley A Carlson

  • Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

    Ravindra Rajakariar;Mark Hilliard;Toby Lawrence;Seema Trivedi

  • Sword and shield: Linked group B streptococcal β-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense

    George Y. Liu;Kelly S. Doran;Toby Lawrence;Nicole Turkson

  • Regulation of macrophage function in tumors: the multifaceted role of NF-κB

    Thorsten Hagemann;Subhra K. Biswas;Toby Lawrence;Antonio Sica

  • An antiinflammatory role for IKKβ through the inhibition of "classical" macrophage activation

    Carol Ho Yan Fong;Magali Bebien;Arnaud Didierlaurent;Ruth Nebauer

  • Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer.

    Anders Etzerodt;Anders Etzerodt;Morgane Moulin;Morgane Moulin;Thomas Koed Doktor;Marcello Delfini

  • Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis.

    Derek W. Gilroy;Paul R. Colville-Nash;Shaun McMaster;Deborah A. Sawatzky

Frequent Co-Authors

Derek W. Gilroy
Derek W. Gilroy University College London
Søren K. Moestrup
Søren K. Moestrup Aarhus University
Marc Dalod
Marc Dalod Centre d’Immunologie de Marseille-Luminy
Bernard Malissen
Bernard Malissen Aix-Marseille University
Michael Karin
Michael Karin University of California, San Diego
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Menno P.J. de Winther
Menno P.J. de Winther University of Amsterdam
Frances R. Balkwill
Frances R. Balkwill Queen Mary University of London
Antonio Sica
Antonio Sica University of Eastern Piedmont Amadeo Avogadro
Kerry-Anne Rye
Kerry-Anne Rye University of New South Wales

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