World's Best Scientists 2026 revealed!
David H. Persing

David H. Persing

D-Index & Metrics

Microbiology

D-Index
86
Citations
23182
World Ranking
848
National Ranking
393

Medicine

D-Index
86
Citations
23379
World Ranking
14274
National Ranking
7213

Overview

What is he best known for?

The fields of study he is best known for:

  • Virus
  • Gene
  • DNA

The scientist’s investigation covers issues in Immunology, Virology, Lyme disease, Borrelia burgdorferi and Babesiosis. His research integrates issues of Internal medicine and Cirrhosis in his study of Immunology. His Virology research includes themes of Bartonella tribocorum and Antigen.

His work deals with themes such as Public health and Tick, which intersect with Lyme disease. In the subject of general Borrelia burgdorferi, his work in Lyme disease microbiology and Erythema chronicum migrans is often linked to Erythema migrans, thereby combining diverse domains of study. David H. Persing combines subjects such as Cohort study, Babesia, Prospective cohort study, Serology and Polymerase chain reaction with his study of Babesiosis.

His most cited work include:

  • Detection of Borrelia burgdorferi DNA by Polymerase Chain Reaction in Synovial Fluid from Patients with Lyme Arthritis (471 citations)
  • Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle (423 citations)
  • Hepatitis C Virus Genotypes in the United States: Epidemiology, Pathogenicity, and Response to Interferon Therapy (351 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Virology, Immunology, Borrelia burgdorferi, Polymerase chain reaction and Lyme disease. His study in Virology is interdisciplinary in nature, drawing from both Antibody, Serology, Antigen and Microbiology. The study incorporates disciplines such as Babesiosis and Internal medicine in addition to Immunology.

His work in Borrelia burgdorferi addresses issues such as Arthritis, which are connected to fields such as Cytokine. While the research belongs to areas of Polymerase chain reaction, he spends his time largely on the problem of Pathology, intersecting his research to questions surrounding Cervix. His research in Lyme disease intersects with topics in Ehrlichiosis, Ehrlichia, Tick, Lyme disease microbiology and Disease.

He most often published in these fields:

  • Virology (43.17%)
  • Immunology (40.97%)
  • Borrelia burgdorferi (22.47%)

What were the highlights of his more recent work (between 2002-2016)?

  • Immunology (40.97%)
  • Immune system (6.61%)
  • Microbiology (16.30%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Immunology, Immune system, Microbiology, Lipid A and TLR4. The concepts of his Immunology study are interwoven with issues in Cancer and CDNA Subtraction. His Microbiology research is multidisciplinary, incorporating elements of Genetics, Hemolysin, 16S ribosomal RNA, Propionibacterium acnes and Polymerase chain reaction.

His work in Lipid A addresses subjects such as Toll-like receptor, which are connected to disciplines such as Nasal administration. His study in TLR4 is interdisciplinary in nature, drawing from both Innate immune system and Pharmacology. David H. Persing has researched Gene in several fields, including Babesiosis, Virology, Serology and Bacteria.

Between 2002 and 2016, his most popular works were:

  • Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agents. (239 citations)
  • Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529 (211 citations)
  • A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease (192 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • DNA

David H. Persing focuses on Lipid A, Immunology, TLR4, Innate immune system and Toll-like receptor. David H. Persing has included themes like Cancer and CDNA Subtraction in his Immunology study. His TLR4 research incorporates elements of Monophosphoryl Lipid A, Adjuvant, Pharmacology and Immunity.

His Immunity course of study focuses on Virus and Microbiology. His work deals with themes such as Molecular biology, Silver stain, Polymerase chain reaction and Protein family, which intersect with Microbiology. His Lipopolysaccharide research includes themes of Molecular mimicry, Agonist, Biochemistry, Structure–activity relationship and In vivo.

Best Publications

  • Detection of Borrelia burgdorferi DNA by Polymerase Chain Reaction in Synovial Fluid from Patients with Lyme Arthritis

    James J. Nocton;Frank Dressler;Barbara J. Rutledge;Paul N. Rys

  • Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle

    Sam R. Telford;Jacqueline E. Dawson;Paula Katavolos;Cynthia K. Warner

  • Concurrent Lyme disease and babesiosis. Evidence for increased severity and duration of illness.

    Peter J. Krause;Sam R. Telford;Andrew Spielman;Vijay Sikand

  • Hepatitis C Virus Genotypes in the United States: Epidemiology, Pathogenicity, and Response to Interferon Therapy

    Nizar N. Zein;Jorge Rakela;Edward L. Krawitt;K. Rajender Reddy

  • Multiplex PCR for identification of methicillin-resistant staphylococci in the clinical laboratory.

    D J Geha;J R Uhl;C A Gustaferro;D H Persing

  • Practice Guidelines for the Treatment of Lyme Disease

    Gary P. Wormser;Robert B. Nadelman;Raymond J. Dattwyler;David T. Dennis

  • Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice.

    Stephen W Barthold;David H. Persing;Audrey L. Armstrong;Ruth A. Peeples

  • Detection of Babesia microti by polymerase chain reaction.

    D. H. Persing;D. Mathiesen;W. F. Marshall;S. R. Telford

  • Molecular diagnostics of infectious diseases

    Yi-Wei Tang;Gary W. Procop;David H. Persing

  • Chronic Lyme borreliosis in the laboratory mouse.

    S. W. Barthold;M. S. de Souza;J. L. Janotka;A. L. Smith

  • Ixodes dammini as a Potential Vector of Human Granulocytic Ehrlichiosis

    P. Pancholi;C. P. Kolbert;P. D. Mitchell;K. D. Reed

  • Ribosomal DNA sequencing as a tool for identification of bacterial pathogens

    Christopher P Kolbert;David H Persing

  • Taking toll: lipid A mimetics as adjuvants and immunomodulators.

    David H Persing;Rhea N Coler;Michael J Lacy;David A Johnson

  • Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agents.

    Jory R Baldridge;Patrick McGowan;Jay T Evans;Christopher Cluff

  • Comparison of Phenotypic and Genotypic Techniques for Identification of Unusual Aerobic Pathogenic Gram-Negative Bacilli

    Yi-Wei Tang;Nicole M. Ellis;Marlene K. Hopkins;Douglas H. Smith

  • Persistent Parasitemia after Acute Babesiosis

    Peter J. Krause;Andrew Spielman;Sam R. Telford;Vijay K. Sikand

  • Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529

    Jay T Evans;Christopher W Cluff;David A Johnson;Michael J Lacy

  • Disease-Specific Diagnosis of Coinfecting Tickborne Zoonoses: Babesiosis, Human Granulocytic Ehrlichiosis, and Lyme Disease

    Peter J. Krause;Kathleen McKay;Charles A. Thompson;Vijay K. Sikand

  • Clinical characteristics and treatment outcome of early Lyme disease in patients with microbiologically confirmed erythema migrans.

    Robert P. Smith;Robert T. Schoen;Daniel W. Rahn;Vijay K. Sikand

  • Infection with a Babesia-Like Organism in Northern California

    David H. Persing;Barbara L. Herwaldt;Carol Glaser;Robert S. Lane

  • Inhibition of secretion of hepatitis B surface antigen by a related presurface polypeptide

    David H. Persing;Harold E. Varmus;Don Ganem

  • Diagnosis and Monitoring of Whipple Disease by Polymerase Chain Reaction

    Nizar N. Ramzan;Edward Loftus;Lawrence J. Burgart;Michele Rooney

  • A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease

    Madeleine M. Fort;Afsaneh Mozaffarian;Axel G. Stöver;Jean da Silva Correia

  • A controlled trial of antimicrobial prophylaxis for Lyme disease after deer-tick bites.

    Eugene D. Shapiro;Michael A. Gerber;Nancy B. Holabird;Anne T. Berg

Frequent Co-Authors

Jorge Rakela
Jorge Rakela Mayo Clinic
Sam R. Telford
Sam R. Telford Tufts University
Stephen W. Barthold
Stephen W. Barthold University of California, Davis
Steven G. Reed
Steven G. Reed Infectious Disease Research Institute
Yi-Wei Tang
Yi-Wei Tang Chongqing Medical University
Tomasz Laskus
Tomasz Laskus Medical University of Warsaw
Peter J. Krause
Peter J. Krause Yale University
Thomas F. Smith
Thomas F. Smith Mayo Clinic
Andrew Spielman
Andrew Spielman Harvard University

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