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Genetics

D-Index
61
Citations
12413
World Ranking
3068
National Ranking
1340

Overview

Kelly T. Hughes is a researcher affiliated with the University of Utah in the United States. Their academic work primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a significant concentration on Molecular Biology and Genetics. Other notable subfields in their research include Ecology, Endocrinology, and Food Science.

The scientist's research topics prominently cover areas such as Bacterial Genetics and Biotechnology, Bacteriophages and microbial interactions, RNA and protein synthesis mechanisms, Escherichia coli research studies, Salmonella and Campylobacter epidemiology, Lipid Membrane Structure and Behavior, and Vibrio bacteria research studies.

Kelly T. Hughes has contributed to several peer-reviewed publications, including:

  • Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion (2020, Nature Communications)
  • Molecular structure of the intact bacterial flagellar basal body (2021, Nature Microbiology)
  • Structural basis of directional switching by the bacterial flagellum (2024, Nature Microbiology)
  • Genetic Analysis of the Salmonella FliE Protein That Forms the Base of the Flagellar Axial Structure (2021, mBio)
  • Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages (2020, Proceedings of the National Academy of Sciences)

These publications appear across several scientific journals, with frequent contributions to the Journal of Bacteriology and bioRxiv (Cold Spring Harbor Laboratory). Other repeated publication venues include Nature Communications, Nature Microbiology, and PLoS Genetics.

Kelly T. Hughes often collaborates with a group of coauthors, with multiple joint publications. Key collaborators include Fabienne F. V. Chevance, Marc Erhardt, Steven Johnson, Emily Furlong, and Justin C. Deme.

Best Publications

  • Coordinating assembly of a bacterial macromolecular machine

    Fabienne F. V. Chevance;Kelly T. Hughes

  • Coupling of flagellar gene expression to flagellar assembly in Salmonella enterica serovar typhimurium and Escherichia coli.

    Gavin S. Chilcott;Kelly T. Hughes

  • Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator

    Kelly T. Hughes;Karen L. Gillen;Melinda J. Semon;Joyce E. Karlinsey

  • THE ANTI-SIGMA FACTORS

    Kelly T. Hughes;Kalai Mathee

  • Regulation of flagellar assembly.

    Phillip Aldridge;Kelly T Hughes

  • Energy source of flagellar type III secretion

    Koushik Paul;Marc Erhardt;Marc Erhardt;Takanori Hirano;David F. Blair

  • Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins.

    Ariane Briegel;Xiaoxiao Li;Alexandrine M. Bilwes;Kelly T. Hughes

  • The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, σ28

    Gary W. Daughdrill;Meggen S. Chadsey;Joyce E. Karlinsey;Kelly T. Hughes

  • Bacterial Nanomachines: The Flagellum and Type III Injectisome

    Marc Erhardt;Keiichi Namba;Kelly T. Hughes

  • Completion of the hook-basal body complex of the Salmonella typhimurium flagellum is coupled to FlgM secretion and fliC transcription

    Joyce E. Karlinsey;Shugo Tanaka;Vera Bettenworth;Shigeru Yamaguchi

  • Transitory cis complementation: a method for providing transposition functions to defective transposons.

    Kelly T. Hughes;John R. Roth

  • Negative regulatory loci coupling flagellin synthesis to flagellar assembly in Salmonella typhimurium.

    K L Gillen;K T Hughes

  • Flagellar Phase Variation in Salmonella enterica Is Mediated by a Posttranscriptional Control Mechanism

    Heather R. Bonifield;Kelly T. Hughes

  • Identification of New Flagellar Genes of Salmonella enterica Serovar Typhimurium

    Jonathan Frye;Joyce E. Karlinsey;Heather R. Felise;Bruz Marzolf

  • Molecular characterization of flgM, a gene encoding a negative regulator of flagellin synthesis in Salmonella typhimurium

    K L Gillen;K T Hughes

  • Conditionally transposition-defective derivative of Mu d1(Amp Lac).

    Kelly T. Hughes;John R. Roth

  • Translation/Secretion Coupling by Type III Secretion Systems

    Joyce E Karlinsey;Jay Lonner;Kit L Brown;Kelly T Hughes

  • The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme.

    Meggen S. Chadsey;Joyce E. Karlinsey;Kelly T. Hughes

  • FimZ Is a Molecular Link between Sticking and Swimming in Salmonella enterica Serovar Typhimurium

    Steven Clegg;Kelly T. Hughes

  • Common and distinct structural features of Salmonella injectisome and flagellar basal body

    Akihiro Kawamoto;Yusuke V. Morimoto;Yusuke V. Morimoto;Tomoko Miyata;Tohru Minamino

Frequent Co-Authors

John R. Roth
John R. Roth University of California, Davis
Keiichi Namba
Keiichi Namba Osaka University
Baldomero M. Olivera
Baldomero M. Olivera University of Utah
Joseph T. Wade
Joseph T. Wade New York State Department of Health
Shin-Ichi Aizawa
Shin-Ichi Aizawa Prefectural University of Hiroshima
Tohru Minamino
Tohru Minamino Osaka University
Theresia E. B. Stradal
Theresia E. B. Stradal Helmholtz Centre for Infection Research
Melvin I. Simon
Melvin I. Simon California Institute of Technology
David R. Hillyard
David R. Hillyard University of Utah
Graham F. Hatfull
Graham F. Hatfull University of Pittsburgh

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