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Genetics

D-Index
99
Citations
32562
World Ranking
785
National Ranking
392

Research.com Recognitions

  • 2020 - Fellow of the American Academy of Arts and Sciences
  • 2013 - ASM Carski Award, American Society for Microbiology
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Graham F. Hatfull is a researcher affiliated with the University of Pittsburgh in the United States. Their work primarily focuses on areas within Environmental Science and Medicine, with particular involvement in subfields such as Ecology, Epidemiology, Molecular Biology, Microbiology, and Radiology, Nuclear Medicine, and Imaging.

The main topics of Hatfull's research include bacteriophages and microbial interactions, Mycobacterium research and diagnosis, microbial infections and disease research, genomics and phylogenetic studies, monoclonal and polyclonal antibodies research, plant virus research studies, and tuberculosis research and epidemiology.

Hatfull's recent publications demonstrate a focus on phage therapy and its applications. Notable papers include:

  • "Phage Therapy: From Biological Mechanisms to Future Directions," 2023, published in Cell
  • "Phage Therapy for Antibiotic-Resistant Bacterial Infections," 2021, published in Annual Review of Medicine
  • "Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease," 2022, published in Clinical Infectious Diseases
  • "Host and Pathogen Response to Bacteriophage Engineered Against Mycobacterium abscessus Lung Infection," 2022, published in Cell
  • "Potent Antibody-Mediated Neutralization Limits Bacteriophage Treatment of a Pulmonary Mycobacterium abscessus Infection," 2021, published in Nature Medicine

The frequent coauthors collaborating with Hatfull include Deborah Jacobs-Sera, Krista G. Freeman, Daniel A. Russell, Rebekah M. Dedrick, and Rebecca A. Garlena.

Hatfull's work is regularly published in venues such as mBio, bioRxiv (Cold Spring Harbor Laboratory), Microbiology Resource Announcements, Journal of Cystic Fibrosis, and Nature Communications.

Hatfull has been recognized by several professional organizations. Awards include the ASM Carski Award from the American Society for Microbiology in 2013, election as a Fellow of the American Association for the Advancement of Science in 2009, and election as a Fellow of the American Academy of Arts and Sciences in 2020.

Best Publications

  • DNA sequence and expression of the B95-8 Epstein—Barr virus genome

    R. Baer;R. Baer;A. T. Bankier;M. D. Biggin;P. L. Deininger

  • New use of BCG for recombinant vaccines.

    C. K. Stover;V. F. De La Cruz;T. R. Fuerst;J. E. Burlein

  • Evolutionary relationships among diverse bacteriophages and prophages: All the world’s a phage

    R W Hendrix;M C Smith;R N Burns;M E Ford

  • Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

    Rebekah M. Dedrick;Carlos A. Guerrero-Bustamante;Rebecca A. Garlena;Daniel A. Russell

  • Origins of Highly Mosaic Mycobacteriophage Genomes

    Marisa L Pedulla;Michael E Ford;Jennifer M Houtz;Tharun Karthikeyan

  • Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.

    Stoyan Bardarov;Svetoslav Bardarov Jr;Martin S Pavelka Jr;Vasan Sambandamurthy

  • Recombineering in Mycobacterium tuberculosis

    Julia C van Kessel;Graham F Hatfull

  • Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

    Anil K. Ojha;Anthony D. Baughn;Dhinakaran Sambandan;Tsungda Hsu

  • Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages

    William R. Jacobs;Raúl G. Barletta;Rupa Udani;John Chan

  • Bacteriophages and their genomes.

    Graham F Hatfull;Roger W Hendrix

  • Genomic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages.

    Robert J Juhala;Michael E Ford;Robert L Duda;Anthony Youlton

  • Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacille Calmette-Guérin.

    Mong Hong Lee;Lisa Pascopella;William R. Jacobs;Graham F. Hatfull

  • Molecular genetics of mycobacteria

    Graham F. Hatfull;William R. Jacobs

  • A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students

    Tuajuanda C. Jordan;Sandra H. Burnett;Susan Carson;Steven M. Caruso

  • Phamerator: a bioinformatic tool for comparative bacteriophage genomics

    Steven G Cresawn;Matt Bogel;Nathan Day;Deborah Jacobs-Sera

  • GroEL1: A Dedicated Chaperone Involved in Mycolic Acid Biosynthesis during Biofilm Formation in Mycobacteria

    Anil Ojha;Mridula Anand;Apoorva Bhatt;Laurent Kremer

  • The origins and ongoing evolution of viruses

    Roger W. Hendrix;Jeffrey G. Lawrence;Graham F. Hatfull;Sherwood Casjens

  • PhagesDB: the actinobacteriophage database.

    Daniel A Russell;Graham F Hatfull

  • Conditionally replicating mycobacteriophages: A system for transposon delivery to Mycobacterium tuberculosis

    Stoyan Bardarov;Jordan Kriakov;Christian Carriere;Shengwei Yu

  • Chapter 12 – Evolutionary Relationships Among Diverse Bacteriophages and Prophages: All The World's a Phage

    Roger W. Hendrix;Graham F. Hatfull;Michael E. Ford

Frequent Co-Authors

Roger W. Hendrix
Roger W. Hendrix University of Pittsburgh
William R. Jacobs
William R. Jacobs Albert Einstein College of Medicine
Sherwood R. Casjens
Sherwood R. Casjens University of Utah
Jeffrey G. Lawrence
Jeffrey G. Lawrence University of Pittsburgh
Laurent Kremer
Laurent Kremer Institut de Recherche en Infectiologie de Montpellier
David I. Hanauer
David I. Hanauer Indiana University of Pennsylvania
Nigel D. F. Grindley
Nigel D. F. Grindley Yale University
Sarah C. R. Elgin
Sarah C. R. Elgin Washington University in St. Louis
John F. Marko
John F. Marko Northwestern University
Richard Losick
Richard Losick Harvard University

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