2026 John F. Marko: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	73	1276	1137	655	571	249	19692

Research.com Recognitions

2006 - Fellow of American Physical Society (APS) Citation For statisticalmechanical theories of DNA and chromosome structure

Overview

John F. Marko is affiliated with Northwestern University in the United States. Their research portfolio spans areas within biochemistry, genetics, and molecular biology, with a focus on molecular biology as the predominant subfield. Other notable subfields of study include plant science, cell biology, biomedical engineering, and ecology.

The main topics of research cover a range of subjects related to genomics, chromatin, nucleic acid chemistry, genetic variations, RNA mechanisms, microtubule dynamics, and DNA repair. Specifically, these topics include:

Genomics and Chromatin Dynamics
DNA and Nucleic Acid Chemistry
Chromosomal and Genetic Variations
RNA Research and Splicing
Microtubule and mitosis dynamics
DNA Repair Mechanisms
RNA Interference and Gene Delivery

Marko has published extensively, with frequent contributions to venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Molecular Cell, Nucleic Acids Research, and Biophysical Journal.

Their notable recent papers include:

Chromosome organization by one-sided and two-sided loop extrusion, 2020, eLife
Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics, 2021, Nature Genetics
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics, 2021, eLife
High-resolution, genome-wide mapping of positive supercoiling in chromosomes, 2021, eLife
The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine, 2020, Molecular Cell

Frequent collaborators in their work include Ronald Biggs, Huanyu Qiao, Andrew D. Stephens, Ryo Kawamura, and Ning Liu, highlighting a collaborative research approach across multiple projects.

John F. Marko was recognized as a Fellow of the American Physical Society (APS) in 2006 for contributions related to statistical mechanical theories of DNA and chromosome structure.

Best Publications

Entropic elasticity of lambda-phage DNA

C Bustamante;JF Marko;ED Siggia;S Smith

2774
Citations
How do site‐specific DNA‐binding proteins find their targets?

Stephen E. Halford;John F. Marko

1066
Citations
Interphase chromosomes undergo constrained diffusional motion in living cells.

W.F Marshall;A Straight;J.F Marko;J Swedlow

769
Citations
Self-organization of domain structures by DNA-loop-extruding enzymes

Elnaz Alipour;John F. Marko

520
Citations
Statistical mechanics of supercoiled DNA

John F. Marko;Eric D. Siggia

507
Citations
Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

Andrew D. Stephens;Edward J. Banigan;Stephen A. Adam;Robert D. Goldman

404
Citations
Bending and Twisting Elasticity of DNA

J. F. Marko;E. D. Siggia

375
Citations
Structural Transitions of a Twisted and Stretched DNA Molecule

J. F. Léger;G. Romano;A. Sarkar;J. Robert

366
Citations
Localized single-stranded bubble mechanism for cyclization of short double helix DNA.

Jie Yan;John F. Marko

330
Citations
Compaction and segregation of sister chromatids via active loop extrusion

Anton Goloborodko;Maksim Viktorovich Imakaev;John F. Marko;Leonid A. Mirny

313
Citations
Chromosome Compaction by Active Loop Extrusion

Anton Goloborodko;John F. Marko;Leonid A. Mirny

306
Citations
Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

Andrew D. Stephens;Patrick Z. Liu;Edward J. Banigan;Edward J. Banigan;Luay M. Almassalha

304
Citations
Fluctuations and supercoiling of DNA.

John F. Marko;Eric D. Siggia

286
Citations
Near-field-magnetic-tweezer manipulation of single DNA molecules.

Jie Yan;Dunja Skoko;John F. Marko

233
Citations
One‐ and three‐dimensional pathways for proteins to reach specific DNA sites

Neil P. Stanford;Mark D. Szczelkun;John F. Marko;Stephen E. Halford

228
Citations
Force and kinetic barriers to unzipping of the DNA double helix.

Simona Cocco;Rémi Monasson;Rémi Monasson;John F. Marko

216
Citations
RecA binding to a single double-stranded DNA molecule: A possible role of DNA conformational fluctuations

J. F. Leger;J. Robert;L. Bourdieu;D. Chatenay;D. Chatenay

214
Citations
Overstretching and force-driven strand separation of double-helix DNA.

Simona Cocco;Jie Yan;Jean Francois Léger;Didier Chatenay

205
Citations
Torque and dynamics of linking number relaxation in stretched supercoiled DNA

John F. Marko

204
Citations
Mitotic chromosomes are chromatin networks without a mechanically contiguous protein scaffold

Michael G. Poirier;John F. Marko

197
Citations

Frequent Co-Authors

Reid C. Johnson University of California, Los Angeles

Jie Yan National University of Singapore

Monica Olvera de la Cruz Northwestern University

Leonid A. Mirny MIT

Robert D. Goldman Northwestern University

Stephen A. Adam Northwestern University

Job Dekker University of Massachusetts Chan Medical School

Nigel D. F. Grindley Yale University

Graham F. Hatfull University of Pittsburgh

Georg Krausch Johannes Gutenberg University of Mainz

External Links

Personal website of John F. Marko

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