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Graham C. Walker

Graham C. Walker

D-Index & Metrics

Genetics

D-Index
113
Citations
51615
World Ranking
485
National Ranking
247

Research.com Recognitions

  • 2013 - Member of the National Academy of Sciences
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2004 - Fellow of the American Academy of Arts and Sciences
  • 1984 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Graham C. Walker is affiliated with MIT in the United States and has a research focus primarily within the field of Biochemistry, Genetics, and Molecular Biology. Their work prominently covers several subfields, including Molecular Biology, Plant Science, Genetics, Oncology, and Molecular Medicine.

The scientist has contributed notably to topics such as DNA Repair Mechanisms, Legume Nitrogen Fixing Symbiosis, Genomics and Chromatin Dynamics, DNA and Nucleic Acid Chemistry, Bacterial Genetics and Biotechnology, RNA and protein synthesis mechanisms, and Antibiotic Resistance in Bacteria.

Frequent coauthors associated with their research include Siva Sankari, Vignesh M. P. Babu, Ke Bian, Michael T. Hemann, and Charley C. Gruber.

Publication venues where Graham C. Walker frequently appears consist of:

  • Proceedings of the National Academy of Sciences
  • Emergency Medicine News
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Microbiology
  • Cell chemical biology

Recent papers detail the scope of their research contributions:

  • "A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria," 2022, Nature Microbiology
  • "REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks," 2020, Proceedings of the National Academy of Sciences
  • "Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality," 2022, Cell chemical biology
  • "Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides," 2021, Science Advances
  • "Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer," 2020, Proceedings of the National Academy of Sciences

Throughout their career, Graham C. Walker has received recognition through various awards. These include becoming a Member of the National Academy of Sciences in 2013, a Fellow of the American Association for the Advancement of Science (AAAS) in 2008, a Fellow of the American Academy of Arts and Sciences in 2004, and a Fellow of the John Simon Guggenheim Memorial Foundation in 1984.

Best Publications

  • DNA Repair and Mutagenesis

    Errol C. Friedberg;Graham C. Walker;Wolfram Siede

  • Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.

    G C Walker

  • Mechanisms of DNA damage, repair, and mutagenesis.

    Nimrat Chatterjee;Graham C. Walker

  • A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance

    Thien-Fah Mah;Betsey Pitts;Brett Pellock;Brett Pellock;Graham C. Walker

  • How rhizobial symbionts invade plants: the Sinorhizobium – Medicago model

    Kathryn M. Jones;Hajime Kobayashi;Bryan William Davies;Michiko E. Taga

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • Antibiotics induce redox-related physiological alterations as part of their lethality

    Daniel J. Dwyer;Peter A. Belenky;Jason H. Yang;I. Cody MacDonald

  • Inducible DNA repair systems.

    Graham C. Walker

  • Exopolysaccharide-deficient mutants of Rhizobium meliloti that form ineffective nodules

    John A. Leigh;Ethan R. Signer;Graham C. Walker

  • Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

    Lauren S. Waters;Brenda K. Minesinger;Mary Ellen Wiltrout;Sanjay D'Souza

  • DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.

    Cynthia J. Kenyon;Graham C. Walker

  • Succinoglycan Is Required for Initiation and Elongation of Infection Threads during Nodulation of Alfalfa by Rhizobium meliloti

    Hai-Ping Cheng;Graham C. Walker

  • Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

    James J. Foti;Babho Devadoss;Jonathan A. Winkler;James J. Collins;James J. Collins

  • Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage

    Peter Belenky;Peter Belenky;Jonathan D. Ye;Caroline B.M. Porter;Caroline B.M. Porter;Caroline B.M. Porter;Nadia R. Cohen;Nadia R. Cohen

  • RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation

    Takehiko Nohmi;John R. Battista;Lori A. Dodson;Graham C. Walker

  • Molecular Determinants of a Symbiotic Chronic Infection

    Katherine E. Gibson;Hajime Kobayashi;Graham C. Walker

  • A novel exopolysaccharide can function in place of the Calcofluor-binding exopolysaccharide in nodulation of alfalfa by Rhizobium meliloti

    Jane Glazebrook;Graham C. Walker

  • Site-directed insertion and deletion mutagenesis with cloned fragments in Escherichia coli.

    S C Winans;S J Elledge;J H Krueger;G C Walker

  • Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

    James J. Foti;Babho Devadoss;Graham C. Walker;Jonathan A. Winkler

  • Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage

    Peter Belenky;Jonathan D. Ye;Nadia R. Cohen;Thomas Ferrante

Frequent Co-Authors

Jane Glazebrook
Jane Glazebrook University of Minnesota
Stephen J. Elledge
Stephen J. Elledge Harvard University
Nelson J. Leonard
Nelson J. Leonard University of Illinois at Urbana-Champaign
Alessio Mengoni
Alessio Mengoni University of Florence
Richard Losick
Richard Losick Harvard University
Omid C. Farokhzad
Omid C. Farokhzad Harvard Medical School

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