Roger Woodgate spends much of his time researching DNA polymerase, Genetics, Molecular biology, DNA replication and DNA polymerase II. His DNA polymerase research is multidisciplinary, relying on both DNA polymerase IV, Polymerase and DNA damage. His work in the fields of Genetics, such as REV1, DNA repair, Eukaryotic DNA replication and Gene, intersects with other areas such as DNA Polymerase Iota.
His Molecular biology research includes elements of DNA polymerase V and DNA polymerase delta. His work is dedicated to discovering how DNA replication, Base pair are connected with Stereochemistry and Base Pair Mismatch and other disciplines. The concepts of his DNA polymerase II study are interwoven with issues in DNA polymerase mu and DNA clamp.
His primary areas of study are DNA polymerase, Molecular biology, DNA, Genetics and Polymerase. The various areas that Roger Woodgate examines in his DNA polymerase study include DNA polymerase II, Mutagenesis and DNA replication. Within one scientific family, Roger Woodgate focuses on topics pertaining to DNA clamp under DNA polymerase II, and may sometimes address concerns connected to Primase.
His Molecular biology research includes themes of DNA polymerase V, DNA repair, SOS response, Escherichia coli and RNA polymerase III. His DNA study integrates concerns from other disciplines, such as Repressor and Cell biology. His biological study spans a wide range of topics, including Primer and DNA synthesis.
His primary areas of investigation include DNA polymerase, Polymerase, Molecular biology, DNA and DNA replication. His DNA polymerase research is multidisciplinary, incorporating elements of Mutagenesis and DNA repair. His Polymerase study combines topics in areas such as Transcriptional regulation, Aptamer and DNA synthesis.
His work carried out in the field of Molecular biology brings together such families of science as Ribonucleotide excision repair and Gene, Escherichia coli. Roger Woodgate has included themes like Biophysics and Genome in his DNA study. His work in DNA replication covers topics such as DNA polymerase delta which are related to areas like DNA polymerase II.
His scientific interests lie mostly in DNA replication, DNA polymerase, DNA repair, Polymerase and SOS response. Roger Woodgate interconnects DNA polymerase delta and Molecular biology in the investigation of issues within DNA replication. His studies deal with areas such as Base excision repair and Ribonucleotide excision repair as well as Molecular biology.
He specializes in DNA polymerase, namely Processivity. The subject of his DNA repair research is within the realm of Biochemistry. In his work, Transcriptional regulation, Post-translational regulation and Protein subunit is strongly intertwined with Mutagenesis, which is a subfield of Polymerase.
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The Y-Family of DNA Polymerases
Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman.
Molecular Cell (2001)
Y-family DNA polymerases and their role in tolerance of cellular DNA damage
Julian E. Sale;Alan R. Lehmann;Roger Woodgate.
Nature Reviews Molecular Cell Biology (2012)
UmuD′2C is an error-prone DNA polymerase, Escherichia coli pol V
Mengjia Tang;Xuan Shen;Ekaterina G. Frank;Mike O’Donnell.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication.
Hong Ling;François Boudsocq;Roger Woodgate;Wei Yang.
Cell (2001)
Identification of additional genes belonging to the LexA regulon in Escherichia coli
Antonio R. Fernández de Henestrosa;Tomoo Ogi;Sayura Aoyagi;David Chafin.
Molecular Microbiology (2002)
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis
Mengjia Tang;Phuong Pham;Xuan Shen;John-Stephen Taylor.
Nature (2000)
What a difference a decade makes: Insights into translesion DNA synthesis
Wei Yang;Roger Woodgate.
Proceedings of the National Academy of Sciences of the United States of America (2007)
The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism.
John P. McDonald;Arthur S. Levine;Roger Woodgate.
Genetics (1997)
UmuD mutagenesis protein of Escherichia coli: Overproduction, purification, and cleavage by RecA
Sabine E. Burckhardt;Roger Woodgate;Richard H. Scheuermann;Harrison Echols.
Proceedings of the National Academy of Sciences of the United States of America (1988)
poliota, a remarkably error-prone human DNA polymerase.
Agnès Tissier;John P. McDonald;Ekaterina G. Frank;Roger Woodgate.
Genes & Development (2000)
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