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Molecular Biology

D-Index
84
Citations
23435
World Ranking
877
National Ranking
462

Overview

Roger Woodgate is affiliated with the National Institutes of Health in the United States. Their research contributions focus primarily on the fields of biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as a subfield.

The main topics of their scientific work cover various aspects of DNA repair mechanisms, bacterial genetics and biotechnology, ubiquitin and proteasome pathways, antibiotic resistance in bacteria, DNA and nucleic acid chemistry, genomics and chromatin dynamics, and cancer therapeutics and mechanisms. These areas reflect a multidisciplinary approach within molecular biosciences.

The scientist has published extensively in notable journals, with frequent publications appearing in:

  • Nucleic Acids Research
  • DNA Repair
  • Journal of Molecular Biology
  • Molecular Microbiology
  • bioRxiv (Cold Spring Harbor Laboratory)

Roger Woodgate's recent papers demonstrate ongoing research activity and include:

  • "USP7 Is a Master Regulator of Genome Stability," 2020, Frontiers in Cell and Developmental Biology
  • "Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair," 2020, Nucleic Acids Research
  • "DNA Polymerase ι Interacts with Both the TRAF-like and UBL1-2 Domains of USP7," 2020, Journal of Molecular Biology
  • "Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome," 2023, eLife
  • "Mysterious and fascinating: DNA polymerase ɩ remains enigmatic 20 years after its discovery," 2020, DNA Repair

The scientist often collaborates with a group of frequent coauthors, indicating consistent research partnerships. These colleagues include:

  • Nicholas W. Ashton
  • John P. McDonald
  • Alexandra Vaisman
  • Irina Bezsonova
  • Myron F. Goodman

Best Publications

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • Y-family DNA polymerases and their role in tolerance of cellular DNA damage

    Julian E. Sale;Alan R. Lehmann;Roger Woodgate

  • UmuD′2C is an error-prone DNA polymerase, Escherichia coli pol V

    Mengjia Tang;Xuan Shen;Ekaterina G. Frank;Mike O’Donnell

  • Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication.

    Hong Ling;François Boudsocq;Roger Woodgate;Wei Yang

  • Identification of additional genes belonging to the LexA regulon in Escherichia coli

    Antonio R. Fernández de Henestrosa;Tomoo Ogi;Sayura Aoyagi;David Chafin

  • Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

    Mengjia Tang;Phuong Pham;Xuan Shen;John-Stephen Taylor

  • What a difference a decade makes: Insights into translesion DNA synthesis

    Wei Yang;Roger Woodgate

  • The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism.

    John P. McDonald;Arthur S. Levine;Roger Woodgate

  • UmuD mutagenesis protein of Escherichia coli: Overproduction, purification, and cleavage by RecA

    Sabine E. Burckhardt;Roger Woodgate;Richard H. Scheuermann;Harrison Echols

  • poliota, a remarkably error-prone human DNA polymerase.

    Agnès Tissier;John P. McDonald;Ekaterina G. Frank;Roger Woodgate

  • Molecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins.

    Bianca Hochhut;Yasmin Lotfi;Didier Mazel;Shah M. Faruque

  • Eukaryotic DNA polymerases: proposal for a revised nomenclature.

    Peter M J Burgers;Eugene V. Koonin;Elspeth Bruford;Luis Blanco

  • Human DNA Polymerase η Promotes DNA Synthesis from Strand Invasion Intermediates of Homologous Recombination

    Michael J. McIlwraith;Alexandra Vaisman;Yilun Liu;Ellen Fanning

  • A plethora of lesion-replicating DNA polymerases

    Roger Woodgate

  • Translesion DNA Polymerases

    Myron F. Goodman;Roger Woodgate

  • Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic polη

    François Boudsocq;Shigenori Iwai;Fumio Hanaoka;Roger Woodgate

  • UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'

    Roger Woodgate;Malini Rajagopalan;Chi Lu;Harrison Echols

  • Misinsertion and bypass of thymine–thymine dimers by human DNA polymerase ι

    Agnès Tissier;Ekaterina G. Frank;John P. McDonald;Shigenori Iwai

  • Controlling the subcellular localization of DNA polymerases ι and η via interactions with ubiquitin

    Brian S Plosky;Antonio E Vidal;Antonio R Fernández de Henestrosa;Mary P McLenigan

  • Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

    Patricia Kannouche;Antonio R. Fernández de Henestrosa;Antonio R. Fernández de Henestrosa;Barry Coull;Antonio E. Vidal

Frequent Co-Authors

Myron F. Goodman
Myron F. Goodman University of Southern California
Michael M. Cox
Michael M. Cox University of Wisconsin–Madison
Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics
Antoine M. van Oijen
Antoine M. van Oijen Illawarra Health and Medical Research Institute
Bryn A. Bridges
Bryn A. Bridges University of Sussex
Wayne A. Hendrickson
Wayne A. Hendrickson Columbia University
Christopher W. Lawrence
Christopher W. Lawrence University of Rochester
Thomas A. Kunkel
Thomas A. Kunkel National Institutes of Health
Mike O'Donnell
Mike O'Donnell Rockefeller University
Alan R. Lehmann
Alan R. Lehmann University of Sussex

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