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Wayne A. Hendrickson

Wayne A. Hendrickson

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
54307
World Ranking
1035
National Ranking
626

Research.com Recognitions

  • 2003 - Canada Gairdner International Award
  • 1997 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences For your contributions to phase angle determination of macromolecular crystals using anomalous dispersion and measurements at multiple wavelengths.
  • 1993 - Member of the National Academy of Sciences
  • 1992 - Fellow of the American Academy of Arts and Sciences
  • 1984 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Wayne A. Hendrickson is affiliated with Columbia University in the United States. Their research primarily falls within the broad domain of Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Plant Science, Materials Chemistry, Cellular and Molecular Neuroscience, and Virology.

The scientist's work addresses several key research topics, including:

  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • RNA and protein synthesis mechanisms
  • Ion channel regulation and function
  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Heat shock proteins research

Recent publications by Wayne A. Hendrickson demonstrate engagement with multiple prestigious journals. Notable papers include:

  • Structure of human GABAB receptor in an inactive state (2020), published in Nature
  • The protein-folding problem: Not yet solved (2022), published in Science
  • Gating movements and ion permeation in HCN4 pacemaker channels (2021), published in Molecular Cell
  • Structure and activity of SLAC1 channels for stomatal signaling in leaves (2021), published in Proceedings of the National Academy of Sciences
  • Symmetric activation and modulation of the human calcium-sensing receptor (2021), published in Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Wayne A. Hendrickson include Oliver B. Clarke, Zhen Gong, Qing Fan, Amos B. Smith, and Ziao Fu.

The scientist's publications often appear in leading research venues such as:

  • Proceedings of the National Academy of Sciences
  • Acta Crystallographica Section A Foundations and Advances
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications

Wayne A. Hendrickson has been recognized with several awards throughout their career, including:

  • Canada Gairdner International Award (2003)
  • Gregori Aminoff Prize, Royal Swedish Academy of Sciences (1997), awarded for contributions to phase angle determination of macromolecular crystals using anomalous dispersion and measurements at multiple wavelengths
  • Member of the National Academy of Sciences (1993)
  • Fellow of the American Academy of Arts and Sciences (1992)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1984)

Best Publications

  • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

    Peter D. Kwong;Richard Wyatt;James Robinson;Raymond W. Sweet

  • The antigenic structure of the HIV gp120 envelope glycoprotein

    Richard Wyatt;Peter D. Kwong;Elizabeth Desjardins;Raymond W. Sweet

  • Determination of Macromolecular Structures from Anomalous Diffraction of Synchrotron Radiation

    Wayne A. Hendrickson

  • Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

    Xiaotian Zhu;Xun Zhao;William F. Burkholder;Alexander Gragerov

  • Structural basis of cell-cell adhesion by cadherins.

    Lawrence Shapiro;Allison M. Fannon;Peter D. Kwong;Andrew Thompson

  • Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD) : a vehicle for direct determination of three-dimensional structure

    W A Hendrickson;J R Horton;D M LeMaster

  • Crystal structure of the tyrosine kinase domain of the human insulin receptor.

    S. R. Hubbard;Lei Wei;L. Ellis;L. Ellis;W. A. Hendrickson;W. A. Hendrickson

  • A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding

    Carlo D. Rizzuto;Richard Wyatt;Richard Wyatt;Nivia Hernández-Ramos;Nivia Hernández-Ramos;Ying Sun;Ying Sun

  • Structure of a C-type mannose-binding protein complexed with an oligosaccharide.

    William I. Weis;Kurt Drickamer;Wayne A. Hendrickson;Wayne A. Hendrickson

  • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

    Peter D. Kwong;Peter D. Kwong;Michael L. Doyle;Michael L. Doyle;David J. Casper;Claudia Cicala

  • Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation.

    W A Hendrickson;A Pähler;J L Smith;Y Satow

  • Structure of the hydrophobic protein crambin determined directly from the anomalous scattering of sulphur

    Wayne A. Hendrickson;Martha M. Teeter

  • Stereochemically restrained refinement of macromolecular structures.

    Wayne A. Hendrickson

  • A structural superfamily of growth factors containing a cystine knot motif.

    Neil Q. McDonald;Wayne A. Hendrickson

  • Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing.

    William I. Weis;Richard Kahn;Roger Fourme;Kurt Drickamer

  • Structure of human follicle-stimulating hormone in complex with its receptor

    Qing R. Fan;Wayne A. Hendrickson

  • Crystal structure of an HIV-binding recombinant fragment of human CD4.

    Seong Eon Ryu;Peter D. Kwong;Alemseged Truneh;Terence G. Porter

  • DC-SIGN-Mediated Internalization of HIV Is Required for Trans-Enhancement of T Cell Infection

    Douglas S. Kwon;Glenn Gregorio;Natacha Bitton;Wayne A. Hendrickson

  • Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein.

    Daniel J. Leahy;Wayne A. Hendrickson;Ikramuddin Aukhil;Harold P. Erickson

  • Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

    Hiroto Yamaguchi;Wayne A. Hendrickson

Frequent Co-Authors

Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Joachim Frank
Joachim Frank Columbia University
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Andrew R. Marks
Andrew R. Marks Columbia University
Janet L. Smith
Janet L. Smith University of Michigan–Ann Arbor
Burkhard Rost
Burkhard Rost Technical University of Munich
Lawrence Shapiro
Lawrence Shapiro Columbia University
Hao Wu
Hao Wu Harvard University
Christopher D. Lima
Christopher D. Lima Memorial Sloan Kettering Cancer Center

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