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Biology and Biochemistry

D-Index
124
Citations
54824
World Ranking
529
National Ranking
331

Overview

Joachim Frank is affiliated with Columbia University in the United States. Their research focuses primarily on the field of Biochemistry, Genetics and Molecular Biology, with particular concentration in Molecular Biology, Structural Biology, Infectious Diseases, Atomic and Molecular Physics, and Optics, as well as Biomedical Engineering.

The scientist's work covers a range of topics including RNA and protein synthesis mechanisms, advanced electron microscopy techniques and applications, RNA modifications and cancer, SARS-CoV-2 and COVID-19 research, force microscopy techniques and applications, viral infections and immunology research, and electron and X-ray spectroscopy techniques.

Joachim Frank has contributed to multiple recent papers such as:

  • A glycan gate controls opening of the SARS-CoV-2 spike protein, 2021, published in Nature Chemistry
  • Retrieving functional pathways of biomolecules from single-particle snapshots, 2020, published in Nature Communications
  • Structure of human GABAB receptor in an inactive state, 2020, published in Nature
  • A glycan gate controls opening of the SARS-CoV-2 spike protein, 2021, published in bioRxiv (Cold Spring Harbor Laboratory)
  • Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells, 2020, published in Science Advances

Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature, Science Advances, Journal of Chemical Information and Modeling, and SSRN Electronic Journal.

Collaborations have been frequent with coauthors such as Zuben P. Brown, Suvrajit Maji, Robert A. Grassucci, Oliver B. Clarke, and F.J. Acosta-Reyes.

Joachim Frank has also authored a book titled CRYO-EM published by the American Chemical Society in 2021.

Best Publications

  • SPIDER AND WEB : PROCESSING AND VISUALIZATION OF IMAGES IN 3D ELECTRON MICROSCOPY AND RELATED FIELDS

    Joachim Frank;Michael Radermacher;Michael Radermacher;Pawel A Penczek;Jun Zhu;Jun Zhu

  • Three-dimensional electron microscopy of macromolecular assemblies : visualization of biological molecules in their native state

    J. Frank

  • Three-Dimensional Electron Microscopy of Macromolecular Assemblies

    Joachim Frank

  • Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

    Leonardo G. Trabuco;Elizabeth Villa;Kakoli Mitra;Joachim Frank;Joachim Frank

  • A ratchet-like inter-subunit reorganization of the ribosome during translocation.

    Joachim Frank;Rajendra Kumar Agrawal;Rajendra Kumar Agrawal

  • Climate change and food safety: A review

    M.C. Tirado;R. Clarke;L.A. Jaykus;A. McQuatters-Gollop

  • Use of multivariate statistics in analysing the images of biological macromolecules

    Marin van Heel;Joachim Frank

  • Locking and unlocking of ribosomal motions.

    Mikel Valle;Andrey V. Zavialov;Jayati Sengupta;Urmila Rawat;Urmila Rawat

  • Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions

    Christian M.T. Spahn;Roland Beckmann;Roland Beckmann;Narayanan Eswar;Pawel A. Penczek

  • Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit.

    Christian M. T. Spahn;Jeffrey S. Kieft;Robert A. Grassucci;Robert A. Grassucci;Pawel A. Penczek

  • Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli

    M. Radermacher;T. Wagenknecht;A. Verschoor;J. Frank

  • Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

    Yongsheng Shi;Dafne Campigli Di Giammartino;Derek Taylor;Ali Sarkeshik

  • Outcome of the First Electron Microscopy Validation Task Force Meeting

    Richard Henderson;Andrej Sali;Matthew L. Baker;Bridget Carragher

  • Focused-ion-beam thinning of frozen-hydrated biological specimens for cryo-electron microscopy.

    Michael Marko;Chyongere Hsieh;Richard Schalek;Joachim Frank;Joachim Frank

  • Three-dimensional reconstruction of single particles embedded in ice.

    Pawel A Penczek;Michael Radermacher;Joachim Frank;Joachim Frank

  • SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs

    Tanvir R Shaikh;Haixiao Gao;William T Baxter;Francisco J Asturias

  • A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome

    Joachim Frank;Jun Zhu;Jun Zhu;Pawel A Penczek;Yanhong Li;Yanhong Li

  • Computer Averaging of Electron Micrographs of 40S Ribosomal Subunits

    Joachim Frank;Adriana Verschoor;Miloslav Boublik

  • Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution

    Irene S Gabashvili;Rajendra K Agrawal;Rajendra K Agrawal;Christian M.T Spahn;Christian M.T Spahn;Robert A Grassucci;Robert A Grassucci

  • Structure of the signal recognition particle interacting with the elongation-arrested ribosome

    Mario Halic;Thomas Becker;Martin R. Pool;Christian M. T. Spahn

Frequent Co-Authors

Robert A. Grassucci
Robert A. Grassucci Columbia University
Pawel A. Penczek
Pawel A. Penczek The University of Texas Health Science Center at Houston
Rajendra K. Agrawal
Rajendra K. Agrawal University at Albany, State University of New York
Carmen A. Mannella
Carmen A. Mannella New York State Department of Health
Christian M. T. Spahn
Christian M. T. Spahn Charité - University Medicine Berlin
Måns Ehrenberg
Måns Ehrenberg Uppsala University
Wayne A. Hendrickson
Wayne A. Hendrickson Columbia University
Klaus Schulten
Klaus Schulten University of Illinois at Urbana-Champaign
José María Carazo
José María Carazo Spanish National Research Council
Andrew R. Marks
Andrew R. Marks Columbia University

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