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Françoise Clerget-Darpoux

Françoise Clerget-Darpoux

D-Index & Metrics

Genetics

D-Index
56
Citations
13700
World Ranking
3479
National Ranking
176

Overview

Françoise Clerget-Darpoux is affiliated with Inserm in France and specializes in biochemistry, genetics, and molecular biology. Their primary research contributions lie within the field of genetics with particular attention to several subfields and topics related to genetic diversity and associations.

The scientist's main topics of work include:

  • Genetic Mapping and Diversity in Plants and Animals
  • Genetic Associations and Epidemiology
  • Genetic and phenotypic traits in livestock

Françoise Clerget-Darpoux has published in scientific journals such as:

  • Genetica
  • Journal of Personalized Medicine

Recent papers by Clerget-Darpoux include:

  • "Heritability: What's the point? What is it not for? A human genetics perspective," published in 2022 in Genetica
  • "The False Dawn of Polygenic Risk Scores for Human Disease Prediction," published in 2022 in Journal of Personalized Medicine

Collaborations are an important aspect of their research output. Frequent coauthors include:

  • Emmanuelle Génin
  • Nicolas Robette
  • Anthony F. Herzig

The research of Françoise Clerget-Darpoux primarily addresses genetic mechanisms and epidemiological factors influencing heritability and disease prediction, as reflected in the recent publications on the limitations of polygenic risk scores and clarifications about heritability concepts in human genetics.

Their work contributes to understanding genetic diversity and mapping, along with investigating associations between genetic traits and phenotypic outcomes in both human and animal populations.

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Early-Onset Autosomal Dominant Alzheimer Disease: Prevalence, Genetic Heterogeneity, and Mutation Spectrum

    Dominique Campion;Cécile Dumanchin;Didier Hannequin;Bruno Dubois

  • Effects of misspecifying genetic parameters in lod score analysis.

    Francoise Clerget-Darpoux;Catherine Bonaiti-Pellie;Joelle Hochez

  • Gene for Chronic Proximal Spinal Muscular Atrophies Maps To Chromosome-5q

    J. Melki;S. Abdelhak;Peter Sheth;M. F. Bachelot

  • Alzheimer's Disease Associated with Mutations in Presenilin 2 is Rare and Variably Penetrant

    R. Sherrington;S. Froelich;S. Sorbi;D. Campion

  • More missense in amyloid gene.

    D.A. Carter;E. Desmarais;M. Bellis;D. Campion

  • Mutations of the presenilin I gene in families with early-onset Alzheimer's disease.

    Dominique Campion;Dominique Campion;Jean-Michel Flaman;Alexis Brice;Didier Hannequin

  • Estimation of the Inbreeding Coefficient through Use of Genomic Data

    Anne Louise Leutenegger;Bernard Prum;Emmanuelle Génin;Christophe Verny

  • Genome search in celiac disease

    Luigi Greco;Gino Corazza;Marie Claude Babron;Fabienne Clot

  • HLA‐DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease

    P. Margaritte-Jeannin;M.C. Babron;M. Bourgey;A.S. Louka

  • New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility.

    Sophie Tezenas du Montcel;Laetitia Michou;Elisabeth Petit-Teixeira;José Osorio

  • Association of TALS Developmental Disorder with Defect in Minor Splicing Component U4atac snRNA

    Patrick Edery;Charles Marcaillou;Mourad Sahbatou;Audrey Labalme

  • Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex

    H Bickeböller;D Campion;A Brice;P Amouyel

  • IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations

    F. Weber;B. Fontaine;I. Cournu-Rebeix;A. Kroner

  • HLA-related genetic risk for coeliac disease

    Mathieu Mb Bourgey;Giuseppe Gc Calcagno;Nadia Nt Tinto;Daniela Dg Gennarelli

  • Tyrosine hydroxylase polymorphisms associated with manic-depressive illness.

    M. Leboyer;A. Malafosse;S. Boularand;D. Campion

  • Association between the extended tau haplotype and frontotemporal dementia.

    Patrice Verpillat;Agnès Camuzat;Didier Hannequin;Catherine Thomas-Anterion

  • Identifying modifier genes of monogenic disease: strategies and difficulties

    Emmanuelle Génin;Emmanuelle Génin;Josué Feingold;Josué Feingold;Françoise Clerget-Darpoux;Françoise Clerget-Darpoux

  • Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis.

    Patrice Verpillat;Patrice Verpillat;Agnès Camuzat;Didier Hannequin;Catherine Thomas-Anterion

  • Refining genetic associations in multiple sclerosis

    D. Booth;R. Heard;G. Stewart;A. Goris

Frequent Co-Authors

Alexis Brice
Alexis Brice Institut du Cerveau
Didier Hannequin
Didier Hannequin Grenoble Alpes University
Dominique Campion
Dominique Campion University of Rouen
Yves Agid
Yves Agid Institut du Cerveau
Bertrand Fontaine
Bertrand Fontaine Université Paris Cité
Thierry Frebourg
Thierry Frebourg Grenoble Alpes University
Bruno Dubois
Bruno Dubois Université Paris Cité
Marion Leboyer
Marion Leboyer Paris-Est Créteil University
Hadi Quesneville
Hadi Quesneville University of Paris-Saclay

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