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Ekaterina Rogaeva

Ekaterina Rogaeva

D-Index & Metrics

Genetics

D-Index
102
Citations
65857
World Ranking
693
National Ranking
21

Medicine

D-Index
107
Citations
69423
World Ranking
6104
National Ranking
236

Overview

Ekaterina Rogaeva is affiliated with the University of Toronto in Canada and has a robust body of research primarily focused on neurological disorders and related molecular biology. Their work spans several interconnected fields within medicine, biochemistry, genetics, and molecular biology.

The main fields of study covered by Rogaeva include Medicine and Biochemistry, Genetics and Molecular Biology. Their subfields of study focus heavily on Neurology, Physiology, Molecular Biology, Genetics, and Psychiatry and Mental Health. This multidisciplinary scope supports their investigation into complex neurodegenerative diseases.

Rogaeva's research covers key topics such as Alzheimer's disease research and treatments, Parkinson's disease mechanisms and treatments, amyotrophic lateral sclerosis research, dementia and cognitive impairment research, neurological diseases and metabolism, epigenetics and DNA methylation, and genetics and neurodevelopmental disorders.

Their recent notable publications include:

  • Early-Onset Alzheimer's Disease: What Is Missing in Research?, 2021, published in Current Neurology and Neuroscience Reports
  • Late-onset vs nonmendelian early-onset Alzheimer disease, 2020, published in Neurology Genetics
  • DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan, 2020, published in Neuroscience Insights
  • Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementia, 2022, published in Brain
  • Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling, 2021, published in Neurology

Collaborations are a significant part of Rogaeva's scientific output. Frequent co-authors include Maria Carmela Tartaglia, Mario Masellis, Sandra E. Black, Anthony E. Lang, and Elizabeth Finger, reflecting a network of scientists working on related neurological and neurodegenerative topics.

Their research contributions are regularly published in prominent venues such as Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), Neurology, Brain, and Brain Communications. These journals and platforms often feature extensive work on neurodegenerative diseases and cognitive disorders.

Best Publications

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

    R. Sherrington;E. I. Rogaev;Y. Liang;E. A. Rogaeva

  • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

    Alan E. Renton;Elisa Majounie;Adrian James Waite;Javier Simón-Sánchez;Javier Simón-Sánchez

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • TREM2 Variants in Alzheimer's Disease

    Rita Guerreiro;Rita Guerreiro;Aleksandra Wojtas;Jose Bras;Minerva Carrasquillo

  • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

    E. I. Rogaev;R. Sherrington;E. A. Rogaeva;G. Levesque

  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

    Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

    Gang Yu;Masaki Nishimura;Shigeki Arawaka;Shigeki Arawaka;Diane Levitan

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

    P. St George-Hyslop;J. Haines;E. Rogaev;E. Rogaev;M. Mortilla;M. Mortilla

  • TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

    Ian R. Mackenzie;Alexandra M. Nicholson;Mohona Sarkar;James Messing

  • Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis

    Jonathan D Rohrer;Jennifer M Nicholas;Jennifer M Nicholas;David M Cash;John van Swieten

  • The Presenilin 1 Protein Is a Component of a High Molecular Weight Intracellular Complex That Contains β-Catenin

    Gang Yu;Fusheng Chen;G. Levesque;M. Nishimura

  • Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

    C Cruchaga;CM Karch;SC Jin;BA Benitez

  • Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

    Janel O Johnson;Erik P Pioro;Ashley Boehringer;Ruth Chia

  • Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes.

    Gyungah Jun;Adam C. Naj;Gary W. Beecham;Li San Wang

Frequent Co-Authors

Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Richard Mayeux
Richard Mayeux Columbia University
P. H. St George-Hyslop
P. H. St George-Hyslop University of Toronto
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Anthony E. Lang
Anthony E. Lang University of Toronto
Sandro Sorbi
Sandro Sorbi University of Florence
John Hardy
John Hardy University College London
Mario Masellis
Mario Masellis Sunnybrook Health Science Centre
Alexis Brice
Alexis Brice Institut du Cerveau
Evgeny I. Rogaev
Evgeny I. Rogaev University of Massachusetts Chan Medical School

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