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P. H. St George-Hyslop

P. H. St George-Hyslop

University of Toronto
Canada

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
54278
World Ranking
1337
National Ranking
39

P. H. St George-Hyslop publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where P. H. St George-Hyslop sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 283 publications — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

P. H. St George-Hyslop D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where P. H. St George-Hyslop sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 102 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Genetics

His primary areas of study are Genetics, Alzheimer's disease, Presenilin, Locus and Pathology. Gene, Gene mapping, Genetic linkage, Genetic marker and Chromosome 21 are the subjects of his Genetics studies. He has researched Alzheimer's disease in several fields, including Antibody, Dementia, Pharmacology and Peptide.

The study incorporates disciplines such as Early-onset Alzheimer's disease and Cell biology in addition to Presenilin. He studied Locus and Amyloid precursor protein that intersect with Amyloid beta, Molecular biology and Beta protein. The various areas that he examines in his Pathology study include Allele and Chromosome 17.

His most cited work include:

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease (3518 citations)
  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. (3218 citations)
  • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene (1764 citations)

What are the main themes of his work throughout his whole career to date?

P. St George-Hyslop focuses on Genetics, Alzheimer's disease, Presenilin, Gene and Degenerative disease. Genetics is closely attributed to Disease in his work. P. St George-Hyslop combines subjects such as Pathogenesis, Allele frequency, Dementia, Age of onset and Apolipoprotein E with his study of Alzheimer's disease.

P. St George-Hyslop interconnects Endocrinology, Mutant, Point mutation and Cell biology in the investigation of issues within Presenilin. His work carried out in the field of Gene brings together such families of science as Molecular biology and Amyloid precursor protein. His PSEN2 study combines topics in areas such as Early-onset Alzheimer's disease and PSEN1.

He most often published in these fields:

  • Genetics (64.17%)
  • Alzheimer's disease (39.17%)
  • Presenilin (41.67%)

What were the highlights of his more recent work (between 2001-2013)?

  • Genetics (64.17%)
  • Presenilin (41.67%)
  • Alzheimer's disease (39.17%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Genetics, Presenilin, Alzheimer's disease, Disease and Amyloid precursor protein. Presenilin is a subfield of Internal medicine that P. St George-Hyslop investigates. His Alzheimer's disease research is multidisciplinary, incorporating perspectives in Immunization, Immunology, Genetically modified mouse, Pharmacology and Degenerative disease.

His Degenerative disease research is classified as research in Pathology. His work deals with themes such as Genetic counseling, Case-control study and PSEN2, which intersect with Mutation. His PSEN2 research is multidisciplinary, relying on both Missense mutation and Exon.

Between 2001 and 2013, his most popular works were:

  • Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4−10 and inhibit cytotoxicity and fibrillogenesis (422 citations)
  • Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4−10 and inhibit cytotoxicity and fibrillogenesis (422 citations)
  • LRRK2 gene in Parkinson disease: Mutation analysis and case control association study (141 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • DNA

His primary scientific interests are in Alzheimer's disease, Genetics, Pharmacology, Immunology and Genetically modified mouse. Alzheimer's disease is the subject of his research, which falls under Pathology. When carried out as part of a general Genetics research project, his work on Allele, Proband and Gene is frequently linked to work in Penetrant, therefore connecting diverse disciplines of study.

His Pharmacology research incorporates elements of Peptide and Antibody, Immunization, Antigen. His research in Immunology intersects with topics in Cognitive decline, Cognitive disorder and Degenerative disease. His Genetically modified mouse research is multidisciplinary, incorporating elements of Neurogenesis, Neuropathology, PI3K/AKT/mTOR pathway and Latrepirdine.

Best Publications

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

    R. Sherrington;E. I. Rogaev;Y. Liang;E. A. Rogaeva

  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.

    A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop

  • TREM2 Variants in Alzheimer's Disease

    Rita Guerreiro;Rita Guerreiro;Aleksandra Wojtas;Jose Bras;Minerva Carrasquillo

  • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

    E. I. Rogaev;R. Sherrington;E. A. Rogaeva;G. Levesque

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

    R. E. Tanzi;J. F. Gusella;P. C. Watkins;G. A. P. Bruns

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

    Tetsuro Murakami;Seema Qamar;Julie Qiaojin Lin;Gabriele S Kaminski Schierle

  • FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

    Seema Qamar;Guo Zhen Wang;Suzanne J. Randle;Francesco Simone Ruggeri

  • Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

    Peter Davies;Judith Resnick;Burton Resnick;Sid Gilman

  • Prediction of probable Alzheimer's disease in memory-impaired patients: A prospective longitudinal study

    M. C. Tierney;J. P. Szalai;W. G. Snow;R. H. Fisher

  • α-Synuclein Membrane Interactions and Lipid Specificity

    Euijung Jo;JoAnne McLaurin;Christopher M. Yip;Peter St. George-Hyslop;Peter St. George-Hyslop

  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

    P. St George-Hyslop;J. Haines;E. Rogaev;E. Rogaev;M. Mortilla;M. Mortilla

  • Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

    Hao Li;Sally Wetten;Li Li;Pamela L. St. Jean

  • Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4−10 and inhibit cytotoxicity and fibrillogenesis

    J McLaurin;R Cecal;M E Kierstead;X Tian

  • The Presenilin 1 Protein Is a Component of a High Molecular Weight Intracellular Complex That Contains β-Catenin

    Gang Yu;Fusheng Chen;G. Levesque;M. Nishimura

  • Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.

    Dun Sheng Yang;Dun Sheng Yang;Philip Stavrides;Panaiyur S. Mohan;Panaiyur S. Mohan;Susmita Kaushik

  • Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

    P. H. St George-Hyslop;J. L. Haines;L. A. Farrer;R. Polinsky

  • Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype

    H. Houlden;M. Baker;H. R. Morris;N. MacDonald

Frequent Co-Authors

Ekaterina Rogaeva
Ekaterina Rogaeva University of Toronto
Paul E. Fraser
Paul E. Fraser University of Toronto
Evgeny I. Rogaev
Evgeny I. Rogaev University of Massachusetts Chan Medical School
James F. Gusella
James F. Gusella Harvard University
Rudolph E. Tanzi
Rudolph E. Tanzi Harvard University
You-Qiang Song
You-Qiang Song University of Hong Kong
Lindsay A. Farrer
Lindsay A. Farrer Boston University
David Westaway
David Westaway University of Alberta
Walter J. Lukiw
Walter J. Lukiw Louisiana State University
Sandro Sorbi
Sandro Sorbi University of Florence

External Links

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Best Scientists Citing P. H. St George-Hyslop

Peter St George-Hyslop

Peter St George-Hyslop

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Publications: 202

John Hardy

John Hardy

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Publications: 170

Rudolph E. Tanzi

Rudolph E. Tanzi

Harvard University

Publications: 138

Alison Goate

Alison Goate

Icahn School of Medicine at Mount Sinai

Publications: 117

Kaj Blennow

Kaj Blennow

University of Gothenburg

Publications: 113

Margaret A. Pericak-Vance

Margaret A. Pericak-Vance

University of Miami

Publications: 108

Ann M. Saunders

Ann M. Saunders

Durham University

Publications: 99

Ralph N. Martins

Ralph N. Martins

Edith Cowan University

Publications: 95

Thomas D. Bird

Thomas D. Bird

University of Washington

Publications: 91

Dennis J. Selkoe

Dennis J. Selkoe

Brigham and Women's Hospital

Publications: 89

Allen D. Roses

Allen D. Roses

Duke University

Publications: 88

Paul E. Fraser

Paul E. Fraser

University of Toronto

Publications: 85

Bradley T. Hyman

Bradley T. Hyman

Harvard University

Publications: 84

Gerard D. Schellenberg

Gerard D. Schellenberg

University of Pennsylvania

Publications: 77

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Harald Hampel

Eisai (United States)

Publications: 75

Dennis W. Dickson

Dennis W. Dickson

Mayo Clinic

Publications: 74

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