His main research concerns Neuroscience, Dopamine, Pharmacology, Addiction and Inhibitory postsynaptic potential. His research in Neuroscience intersects with topics in Neurotransmission and Cannabinoid receptor. His work in Cannabinoid receptor addresses issues such as GABAB receptor, which are connected to fields such as Voltage-dependent calcium channel.
His research in Dopamine is mostly concerned with Dopaminergic. In the subject of general Pharmacology, his work in Designer drug is often linked to Pyrovalerone, thereby combining diverse domains of study. His studies in Nucleus accumbens integrate themes in fields like Cannabinoid and Long-term depression.
His scientific interests lie mostly in Neuroscience, Dopamine, Internal medicine, Endocrinology and Cannabinoid receptor. Carl R. Lupica has researched Neuroscience in several fields, including Synaptic plasticity, Glutamate receptor and Neurotransmission. His Dopamine course of study focuses on Cell biology and Secretion.
Carl R. Lupica focuses mostly in the field of Endocrinology, narrowing it down to topics relating to Agonist and, in certain cases, GABAA receptor, Schaffer collateral and Antagonist. His Cannabinoid receptor study combines topics in areas such as Hippocampus, Cannabinoid and Pharmacology. His Pharmacology study incorporates themes from Adenosine, Cannabinoid receptor antagonist, Adenosine A1 receptor, Adenosine receptor and Cannabinoid Receptor Agonists.
Carl R. Lupica spends much of his time researching Neuroscience, Cannabinoid, Cannabinoid receptor, Endocannabinoid system and Cannabis. His work on Addiction, Dopamine, Optogenetics and Excitatory postsynaptic potential as part of general Neuroscience research is frequently linked to Context, bridging the gap between disciplines. His Addiction study combines topics from a wide range of disciplines, such as Habenula and Cholinergic.
His study focuses on the intersection of Cannabinoid receptor and fields such as Synaptic plasticity with connections in the field of Hippocampus, Neuroplasticity, Postsynaptic potential, Central nervous system and Neurotransmission. In his study, Secretion, Sigma-1 receptor and Ventral tegmental area is strongly linked to Cell biology, which falls under the umbrella field of Endocannabinoid system. His Synthetic cannabinoids study deals with Pharmacology intersecting with Allosteric regulation, Indole test and Human brain.
His primary areas of investigation include Neuroscience, Optogenetics, Context, Monoaminergic and Cannabinoid. Neuroscience is closely attributed to Pharmacology in his research. The study incorporates disciplines such as Corticotropin-releasing hormone, Thalamus, Septal nuclei, Central nucleus of the amygdala and Stria terminalis in addition to Optogenetics.
His Monoaminergic research integrates issues from Cholinergic, Self-administration, Muscimol, Habenula and Addiction. His work deals with themes such as Baclofen and GABAergic, which intersect with Addiction. His research in Cannabinoid focuses on subjects like Hippocampal formation, which are connected to Synaptic plasticity.
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It could be habit forming: drugs of abuse and striatal synaptic plasticity.
Gregory L. Gerdeman;John G. Partridge;Carl R. Lupica;David M. Lovinger.
Trends in Neurosciences (2003)
Mechanisms of cannabinoid inhibition of GABA(A) synaptic transmission in the hippocampus.
Alexander F. Hoffman;Carl R. Lupica.
The Journal of Neuroscience (2000)
Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products.
Michael H Baumann;John S Partilla;Kurt R Lehner;Eric B Thorndike.
Neuropsychopharmacology (2013)
Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area.
Alice H. Luo;Pouya Tahsili-Fahadan;Roy A. Wise;Carl R. Lupica.
Science (2011)
Marijuana and cannabinoid regulation of brain reward circuits.
Carl R Lupica;Arthur C Riegel;Alexander F Hoffman.
British Journal of Pharmacology (2004)
Endocannabinoid release from midbrain dopamine neurons: a potential substrate for cannabinoid receptor antagonist treatment of addiction.
Carl R. Lupica;Arthur C. Riegel.
Neuropharmacology (2005)
Single rodent mesohabenular axons release glutamate and GABA
David H Root;Carlos A Mejias-Aponte;Shiliang Zhang;Hui-Ling Wang.
Nature Neuroscience (2014)
Independent presynaptic and postsynaptic mechanisms regulate endocannabinoid signaling at multiple synapses in the ventral tegmental area
Arthur C. Riegel;Carl R. Lupica.
The Journal of Neuroscience (2004)
Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.
Alexander F. Hoffman;Murat Oz;Tara Caulder;Carl R. Lupica.
The Journal of Neuroscience (2003)
Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.
Alexander F. Hoffman;Carl R. Lupica.
Journal of Neurophysiology (2001)
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