Bruce T. Hope mainly investigates Neuroscience, Endocrinology, Internal medicine, Nucleus accumbens and Addiction. His work in the fields of Neuroscience, such as Central nervous system, intersects with other areas such as Ventral Medial Prefrontal Cortex. His work focuses on many connections between Endocrinology and other disciplines, such as Self-administration, that overlap with his field of interest in Extinction and Protein kinase A.
His Nucleus accumbens study combines topics from a wide range of disciplines, such as Regulation of gene expression, Ventral tegmental area and Gene expression, FOSB. His Addiction research includes elements of Pharmacology, Incubation and Sensitization. As part of one scientific family, Bruce T. Hope deals mainly with the area of Signal transduction, narrowing it down to issues related to the Nervous system, and often Nitric oxide synthase, Nitric oxide, Diaphorase and NADPH dehydrogenase.
Bruce T. Hope spends much of his time researching Neuroscience, Internal medicine, Endocrinology, Nucleus accumbens and Pharmacology. His study in the field of Addiction, Craving, Extinction and Premovement neuronal activity is also linked to topics like Infralimbic cortex. His Craving study deals with Incubation intersecting with Abstinence and Cocaine craving.
In his research on the topic of Internal medicine, CREB, Epigenetics of cocaine addiction and MAPK/ERK pathway is strongly related with Protein kinase A. His research in Endocrinology tackles topics such as AMPA receptor which are related to areas like Glutamatergic. His Nucleus accumbens research includes themes of Ventral tegmental area, Immediate early gene, Striatum and Sensitization.
Bruce T. Hope mostly deals with Neuroscience, Addiction, Incubation, Pharmacology and Craving. Retrograde tracing, Dopamine, Nucleus accumbens, Food seeking and Extinction are among the areas of Neuroscience where Bruce T. Hope concentrates his study. Bruce T. Hope interconnects Midbrain, Self-administration and Extinction in the investigation of issues within Dopamine.
His Nucleus accumbens research integrates issues from Long-term potentiation, Integrin and Signal transduction, Focal adhesion. His research integrates issues of Cocaine seeking and Engram in his study of Addiction. In his work, Drug is strongly intertwined with Abstinence, which is a subfield of Craving.
His main research concerns Neuroscience, Dopamine, Retrograde tracing, Nucleus accumbens and Engram. His biological study spans a wide range of topics, including Selective inhibition, Cholera toxin, Midbrain, Self-administration and Extinction. His Retrograde tracing research is multidisciplinary, incorporating perspectives in Medium spiny neuron, Globus pallidus, Ventral pallidum and Ventral tegmental area.
His work on Engram is being expanded to include thematically relevant topics such as Addiction.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Neuronal NADPH diaphorase is a nitric oxide synthase.
Bruce T. Hope;Gregory J. Michael;Karl M. Knigge;Steven R. Vincent.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Neuroadaptation. Incubation of cocaine craving after withdrawal.
Jeffrey W. Grimm;Bruce T. Hope;Roy A. Wise;Yavin Shaham.
Nature (2001)
Drug addiction: A model for the molecular basis of neural plasticity
Eric J. Nestler;Bruce T. Hope;Katherine L. Widnell.
Neuron (1993)
Dopamine Uptake through the Norepinephrine Transporter in Brain Regions with Low Levels of the Dopamine Transporter: Evidence from Knock-Out Mouse Lines
José A. Morón;Alicia Brockington;Roy A. Wise;Beatriz A. Rocha.
The Journal of Neuroscience (2002)
Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments
Bruce T. Hope;Heather E. Nye;Max B. Kelz;David W. Self.
Neuron (1994)
Neurons that say NO
Steven R. Vincent;Bruce T. Hope.
Trends in Neurosciences (1992)
Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain
Emmanuel S. Onaivi;Emmanuel S. Onaivi;Hiroki Ishiguro;Jian Ping Gong;Sejal Patel.
Annals of the New York Academy of Sciences (2006)
Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine
Bruce Hope;Barry Kosofsky;Steven E. Hyman;Eric J. Nestler.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Time-Dependent Increases in Brain-Derived Neurotrophic Factor Protein Levels within the Mesolimbic Dopamine System after Withdrawal from Cocaine: Implications for Incubation of Cocaine Craving
Jeffrey W. Grimm;Lin Lu;Teruo Hayashi;Bruce T. Hope.
The Journal of Neuroscience (2003)
Neurobiology of the incubation of drug craving
Charles L. Pickens;Mikko Airavaara;Florence Theberge;Sanya Fanous.
Trends in Neurosciences (2011)
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