D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 63 Citations 11,756 174 World Ranking 4512 National Ranking 53

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Neurotransmitter

Francisco Ciruela mostly deals with Receptor, Cell biology, Biochemistry, Neuroscience and Adenosine A2A receptor. His Receptor research incorporates themes from Signal transduction and Binding site. His research integrates issues of Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 6, Purinergic signalling, Adenosine A2B receptor and Metabotropic glutamate receptor 5 in his study of Cell biology.

His Biochemistry research focuses on Förster resonance energy transfer and how it connects with Biophysics and Bimolecular fluorescence complementation. His Neuroscience research is multidisciplinary, incorporating elements of Agonist, Glutamatergic and Neurotransmission. His Adenosine A2A receptor course of study focuses on Dopamine receptor D2 and Neurotransmitter receptor, GABAergic and Dopamine receptor.

His most cited work include:

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers (465 citations)
  • Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER (377 citations)
  • Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. (316 citations)

What are the main themes of his work throughout his whole career to date?

Francisco Ciruela mainly focuses on Receptor, Cell biology, G protein-coupled receptor, Neuroscience and Adenosine. His Receptor research incorporates elements of Biophysics and Pharmacology. His Cell biology research integrates issues from 5-HT5A receptor, Adenosine A2B receptor, Muscarinic acetylcholine receptor M5 and Metabotropic glutamate receptor.

The study incorporates disciplines such as Rhodopsin-like receptors, Allosteric regulation and Förster resonance energy transfer in addition to G protein-coupled receptor. He works mostly in the field of Neuroscience, limiting it down to topics relating to Adenosine A2A receptor and, in certain cases, Dopamine receptor D2, Parkinson's disease and Endocrinology, as a part of the same area of interest. As a part of the same scientific study, Francisco Ciruela usually deals with the Adenosine, concentrating on Adenosine receptor and frequently concerns with Schizophrenia.

He most often published in these fields:

  • Receptor (40.78%)
  • Cell biology (33.73%)
  • G protein-coupled receptor (30.59%)

What were the highlights of his more recent work (between 2015-2021)?

  • Neuroscience (29.80%)
  • Receptor (40.78%)
  • Adenosine (21.96%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Neuroscience, Receptor, Adenosine, Adenosine A2A receptor and Pharmacology. His Neuroscience study incorporates themes from Synaptic plasticity, Glutamate receptor, Adenosinergic and Neurotransmission. His specific area of interest is Receptor, where Francisco Ciruela studies G protein-coupled receptor.

G protein-coupled receptor is a subfield of Cell biology that Francisco Ciruela studies. His research on Adenosine concerns the broader Biochemistry. His study looks at the relationship between Adenosine A2A receptor and topics such as Neurochemical, which overlap with Sensory gating.

Between 2015 and 2021, his most popular works were:

  • Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors (57 citations)
  • Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors (57 citations)
  • Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes (55 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Neurotransmitter

Francisco Ciruela mainly investigates Adenosine, Adenosine A2A receptor, Neuroscience, Receptor and Dopamine receptor D2. The concepts of his Adenosine study are interwoven with issues in Hippocampus, Adenylyl cyclase, Adenosine receptor and Cell biology. His biological study spans a wide range of topics, including Striatum, Dopamine, Endocannabinoid system and Postsynaptic potential.

His Neuroscience research is multidisciplinary, relying on both Purinergic receptor, Cannabinoid and Cannabinoid receptor. His Receptor study necessitates a more in-depth grasp of Biochemistry. His Dopamine receptor D2 study combines topics in areas such as G protein-coupled receptor and Heteromer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján.
The Journal of Neuroscience (2006)

590 Citations

Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER

Meritxell Canals;Daniel Marcellino;Francesca Fanelli;Francisco Ciruela.
Journal of Biological Chemistry (2003)

509 Citations

Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.

Sergi Ferré;Marzena Karcz-Kubicha;Bruce T. Hope;Patrizia Popoli.
Proceedings of the National Academy of Sciences of the United States of America (2002)

409 Citations

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

Paulina Carriba;Gemma Navarro;Francisco Ciruela;Sergi Ferré.
Nature Methods (2008)

331 Citations

Cell surface adenosine deaminase: Much more than an ectoenzyme

Rafael Franco;Vicent Casadó;Francisco Ciruela;Carles Saura.
Progress in Neurobiology (1997)

287 Citations

Receptor heteromerization in adenosine A2A receptor signaling Relevance for striatal function and Parkinson’s disease

Kjell Fuxe;L. F. Agnati;K. Jacobsen;J. Hillion.
Neurology (2003)

284 Citations

METABOTROPIC GLUTAMATE TYPE 5, DOPAMINE D2 AND ADENOSINE A2A RECEPTORS FORM HIGHER-ORDER OLIGOMERS IN LIVING CELLS

Nuria Cabello;Jorge Gandía;Daniela C. G. Bertarelli;Masahiko Watanabe.
Journal of Neurochemistry (2009)

279 Citations

Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.

Paulina Carriba;Oskar Ortiz;Kshitij Patkar;Zuzana Justinova;Zuzana Justinova.
Neuropsychopharmacology (2007)

268 Citations

An Update on Adenosine A2A-Dopamine D2 Receptor Interactions: Implications for the Function of G Protein-Coupled Receptors

Sergi Ferré;César Quiroz;A S Woods;Rodrigo Antunes Cunha.
Current Pharmaceutical Design (2008)

264 Citations

Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.

Francisco Ciruela;Javier Burgueño;Vicent Casadó;Meritxell Canals.
Analytical Chemistry (2004)

255 Citations

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