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Biology and Biochemistry

D-Index
68
Citations
14325
World Ranking
7909
National Ranking
128

Overview

Vicent Casadó is affiliated with the University of Barcelona in Spain, where their research primarily focuses on Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. Within these broader fields, their work extensively covers subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Pharmacology, Physiology, and Psychiatry and Mental Health.

The main topics of Casadó's research include Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Cannabis and Cannabinoid Research, Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, Pharmacological Receptor Mechanisms and Effects, and Adenosine and Purinergic Signaling.

Casadó's recent publications illustrate a focus on complex receptor interactions and their pharmacological roles. Selected recent papers include:

  • Control of glutamate release by complexes of adenosine and cannabinoid receptors (2020) published in BMC Biology
  • Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants (2022) published in Frontiers in Endocrinology
  • Preferential Gs protein coupling of the galanin Gal1 receptor in the µ-opioid-Gal1 receptor heterotetramer (2022) published in Pharmacological Research
  • Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease (2020) published in eLife
  • Altered Signaling in CB1R-5-HT2AR Heteromers in Olfactory Neuroepithelium Cells of Schizophrenia Patients is Modulated by Cannabis Use (2020) published in Schizophrenia Bulletin

The publication venues where Casadó frequently publishes research are specialized journals in pharmacology, neuroscience, and medicinal chemistry. The most common venues include:

  • Pharmacological Research
  • Neuroscience Applied
  • Journal of Medicinal Chemistry
  • Expert Opinion on Drug Discovery
  • Molecular Psychiatry

Collaborations are evident in Casadó's work, with frequent coauthors including Estefanía Moreno, Sergi Ferré, Verònica Casadó-Anguera, Leonardo Pardo, and Nil Casajuana-Martín. These partnerships reflect a collaborative research environment often seen in complex biomedical studies.

Best Publications

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

    Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján

  • Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

    Joëlle A. Hillion;Meritxell Canals;Maria Torvinen;Vicent Casado

  • G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

    Sergi Ferré;Vicent Casadó;Lakshmi A. Devi;Marta Filizola

  • Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

    Silvia Ginés;Joëlle Hillion;Maria Torvinen;Stèphane Le Crom

  • Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.

    Sergi Ferré;Marzena Karcz-Kubicha;Bruce T. Hope;Patrizia Popoli

  • Detection of heteromerization of more than two proteins by sequential BRET-FRET.

    Paulina Carriba;Gemma Navarro;Francisco Ciruela;Sergi Ferré

  • Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.

    Paulina Carriba;Oskar Ortiz;Kshitij Patkar;Zuzana Justinova;Zuzana Justinova

  • Cell surface adenosine deaminase: Much more than an ectoenzyme

    Rafael Franco;Vicent Casadó;Francisco Ciruela;Carles Saura

  • Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.

    Lucía Callén;Lucía Callén;Estefanía Moreno;Estefanía Moreno;Pedro Barroso-Chinea;David Moreno-Delgado;David Moreno-Delgado

  • Identification of dopamine D1-D3 receptor heteromers: Indications for a role of synergistic D1-D3 receptor interactions in the striatum

    Daniel Marcellino;Sergi Ferré;Vicent Casadó;Antonio Cortés

  • Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.

    Francisco Ciruela;Javier Burgueño;Vicent Casadó;Meritxell Canals

  • A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.

    Ester Angulo;Vicent Casadó;Josefa Mallol;Enric I. Canela

  • Metabotropic Glutamate 1α and Adenosine A1 Receptors Assemble into Functionally Interacting Complexes

    Francisco Ciruela;Francisco Ciruela;Marisol Escriche;Javier Burgueño;Ester Angulo

  • Evidence for adenosine/dopamine receptor interactions: indications for heteromerization.

    Rafael Franco;Sergi Ferre;Luigi Agnati;Maria Torvinen

  • Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function.

    Carla Ferrada;Sergi Ferré;Vicent Casadó;Antonio Cortés

  • Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

    Gemma Navarro;Estefanía Moreno;Marisol Aymerich;Daniel Marcellino

  • Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

    Sergio González;David Moreno-Delgado;Estefanía Moreno;Kamil Pérez-Capote

  • Immunological identification of A1 adenosine receptors in brain cortex

    F. Ciruela;V. Casadó;J. Mallol;E. I. Canela

  • Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors.

    Carla Ferrada;Estefanía Moreno;Vicent Casadó;Gerold Bongers

  • Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders

    Sergi Ferré;Francisco Ciruela;Meritxell Canals;Daniel Marcellino

Frequent Co-Authors

Rafael Franco
Rafael Franco University of Barcelona
Enric I. Canela
Enric I. Canela University of Barcelona
Josefa Mallol
Josefa Mallol University of Barcelona
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
Carmen Lluis
Carmen Lluis University of Barcelona
Gemma Navarro
Gemma Navarro University of Barcelona
Francisco Ciruela
Francisco Ciruela University of Barcelona
Kjell Fuxe
Kjell Fuxe Karolinska Institute
Leonardo Pardo
Leonardo Pardo Autonomous University of Barcelona
José L. Lanciego
José L. Lanciego University of Navarra

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