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Rashmi Kothary

Rashmi Kothary

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
12241
World Ranking
9836
National Ranking
336

Overview

Rashmi Kothary is affiliated with the Ottawa Hospital in Canada and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans numerous subfields including Molecular Biology, Genetics, Surgery, Cellular and Molecular Neuroscience, and Developmental Neuroscience.

Their research topics focus on Neurogenetic and Muscular Disorders Research, RNA modifications and cancer, RNA Research and Splicing, Muscle Physiology and Disorders, Neurogenesis and neuroplasticity mechanisms, Congenital Anomalies and Fetal Surgery, and MicroRNA in disease regulation.

Recent publications authored or co-authored by Rashmi Kothary include the following:

  • Curing SMA: Are we there yet? (2022, Gene Therapy)
  • Metabolic Dysfunction in Spinal Muscular Atrophy (2021, International Journal of Molecular Sciences)
  • MicroRNAs in oligodendrocyte development and remyelination (2022, Journal of Neurochemistry)
  • SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease (2021, Cellular and Molecular Gastroenterology and Hepatology)
  • Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy (2023, Nature Biomedical Engineering)

Frequently collaborating authors include:

  • Yves De Repentigny
  • Ariane Beauvais
  • Marc-Olivier Deguise
  • Rebecca Yaworski
  • Aoife Reilly

Rashmi Kothary has published repeatedly in several scientific journals, most notably in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuromuscular Diseases
  • Glia
  • Neuromuscular Disorders
  • Gene Therapy

Best Publications

  • Correction: Corrigendum: Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line

    Sheila Smiley;Philip E. Nickerson;Lacrimioara Comanita;Narsis Daftarian

  • Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice

    R. Kothary;S. Clapoff;S. Darling;M.D. Perry

  • A SEQUENCE MOTIF FOUND IN A DROSOPHILA HETEROCHROMATIN PROTEIN IS CONSERVED IN ANIMALS AND PLANTS

    P B Singh;J R Miller;J Pearce;R Kothary

  • The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1.

    Arthur Brown;Gilbert Bernier;Martine Mathieu;Janet Rossant;Janet Rossant

  • A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube

    R. Kothary;S. Clapoff;A. Brown;R. Campbell

  • Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity

    D. Jonathan Horsford;Minh-Thanh T. Nguyen;Grant C. Sellar;Rashmi Kothary

  • The Splotch mutation interferes with muscle development in the limbs

    T. Franz;R. Kothary;M.A.H. Surani;Z. Halata

  • Genome imprinting and development in the mouse

    M A Surani;R Kothary;N D Allen;P B Singh

  • MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium.

    Steven M. Kolodziejczyk;Ling Wang;Kim Balazsi;Yves DeRepentigny

  • Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model

    Mélissa Bowerman;Ariane Beauvais;Ariane Beauvais;Carrie L. Anderson;Carrie L. Anderson;Rashmi Kothary

  • Glucose Metabolism and Pancreatic Defects in Spinal Muscular Atrophy

    Melissa Bowerman;Kathryn J. Swoboda;John Paul Michalski;John Paul Michalski;Gen Sheng Wang

  • The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis

    James Dr Knight;James Dr Knight;Rashmi Kothary;Rashmi Kothary

  • Smn Depletion Alters Profilin II Expression and Leads to Upregulation of the RhoA/ROCK Pathway and Defects in Neuronal Integrity

    Mélissa Bowerman;Dina Shafey;Rashmi Kothary

  • SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2β1

    Philip J. Young;Christine J. DiDonato;Diane Hu;Rashmi Kothary

  • Polytene chromosomes in mouse trophoblast giant cells

    S. Varmuza;V. Prideaux;R. Kothary;J. Rossant

  • SMN, profilin IIa and plastin 3: A link between the deregulation of actin dynamics and SMA pathogenesis

    Mélissa Bowerman;Mélissa Bowerman;Carrie L. Anderson;Carrie L. Anderson;Ariane Beauvais;Ariane Beauvais;Pietro Pilo Boyl

  • A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.

    Mélissa Bowerman;Lyndsay M. Murray;Ariane Beauvais;Bruno Pinheiro

  • Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy

    Melissa Bowerman;Melissa Bowerman;Lyndsay M Murray;Justin G Boyer;Justin G Boyer;Carrie L Anderson

  • Transgenic Expression of the Activating Natural Killer Receptor Ly49H Confers Resistance to Cytomegalovirus in Genetically Susceptible Mice

    Seung-Hwan Lee;Ahmed Zafer;Yves de Repentigny;Rashmi Kothary

  • Lung tumors in mice expressing an antisense RARbeta2 transgene.

    Jacques Bérard;Farida Laboune;Myhala Mukuna;Serge Massé

Frequent Co-Authors

Robin J. Parks
Robin J. Parks Ottawa Hospital
Janet Rossant
Janet Rossant University of Toronto
Bernard J. Jasmin
Bernard J. Jasmin University of Ottawa
Thomas H. Gillingwater
Thomas H. Gillingwater University of Edinburgh
Bernard L. Schneider
Bernard L. Schneider École Polytechnique Fédérale de Lausanne
Christian L. Lorson
Christian L. Lorson University of Missouri
Mary-Ellen Harper
Mary-Ellen Harper University of Ottawa
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
Silvia M. Vidal
Silvia M. Vidal McGill University
Sheila C. Barton
Sheila C. Barton University of Cambridge

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