2026 Aleksander S. Popel: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	87	2873	2644	1476	1329	447	23929

Research.com Recognitions

2003 - Fellow of the American Society of Mechanical Engineers
1994 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Aleksander S. Popel is affiliated with Johns Hopkins University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, focusing on areas related to Oncology, Molecular Biology, Immunology, Cancer Research, and Modeling and Simulation.

The main topics covered in their scientific work include:

Cancer Immunotherapy and Biomarkers
Cancer Genomics and Diagnostics
Single-cell and spatial transcriptomics
Angiogenesis and VEGF in Cancer
Mathematical Biology Tumor Growth
Immune cells in cancer
Cancer Cells and Metastasis

The scientist has published extensively, with several notable recent papers including:

Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence, 2023, Genome Medicine
Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma, 2022, Frontiers in Immunology
Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers, 2022, Cancer Research
Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer, 2020, Frontiers in Physiology
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling, 2024, npj Digital Medicine

Frequent co-authors collaborating with Aleksander S. Popel include:

Hanwen Wang
Elizabeth M. Jaffee
Elana J. Fertig
Mark Yarchoan
Atul Deshpande

The scientist has published frequently in venues such as:

bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
iScience
The FASEB Journal
Journal for ImmunoTherapy of Cancer

Aleksander S. Popel has contributed to book publications as well, including a title published by Frontiers Media in 2024 named Innovative Pharmacometric Approaches to Inform Drug Development and Clinical Use.

Recognition in their career includes being named a Fellow of the American Society of Mechanical Engineers in 2003 and a Fellow of the Indian National Academy of Engineering (INAE) in 1994.

Best Publications

MICROCIRCULATION AND HEMORHEOLOGY

Aleksander S. Popel;Paul C. Johnson

994
Citations
Large deformation of red blood cell ghosts in a simple shear flow

C. D. Eggleton;A. S. Popel

519
Citations
Theory of oxygen transport to tissue.

Aleksander S. Popel

503
Citations
Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer

C Kut;F Mac Gabhann;A S Popel

349
Citations
Nitric oxide in the vasculature: where does it come from and where does it go? A quantitative perspective.

Kejing Chen;Roland N. Pittman;Aleksander S. Popel

343
Citations
Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

Prakash Vempati;Aleksander S. Popel;Feilim Mac Gabhann

340
Citations
A two-phase model for flow of blood in narrow tubes with increased effective viscosity near the wall

Maithili Sharan;Aleksander S. Popel

340
Citations
Red blood cell aggregation and dissociation in shear flows simulated by lattice Boltzmann method

Junfeng Zhang;Paul C. Johnson;Aleksander S. Popel

325
Citations
A theoretical analysis of the effect of the particulate nature of blood on oxygen release in capillaries

William J. Federspiel;Aleksander S. Popel

322
Citations
Blood Flow and Cell-Free Layer in Microvessels

Dmitry A. Fedosov;Bruce Caswell;Aleksander S. Popel;George E.M. Karniadakis

322
Citations
Effect of erythrocyte aggregation on velocity profiles in venules

Jeffrey J. Bishop;Patricia R. Nance;Aleksander S. Popel;Marcos Intaglietta

315
Citations
A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use

Florence T.H. Wu;Marianne O. Stefanini;Feilim Mac Gabhann;Christopher D. Kontos

268
Citations
Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows

Junfeng Zhang;Paul C. Johnson;Aleksander S. Popel

266
Citations
An immersed boundary lattice Boltzmann approach to simulate deformable liquid capsules and its application to microscopic blood flows

Junfeng Zhang;Paul C Johnson;Aleksander S Popel

264
Citations
Impaired Angiogenesis After Hindlimb Ischemia in Type 2 Diabetes Mellitus Differential Regulation of Vascular Endothelial Growth Factor Receptor 1 and Soluble Vascular Endothelial Growth Factor Receptor 1

Surovi Hazarika;Ayotunde O. Dokun;Yongjun Li;Aleksander S. Popel

262
Citations
Systems Biology of Vascular Endothelial Growth Factors

Feilim Mac Gabhann;Aleksander S. Popel

250
Citations
A computational study of the effect of capillary network anastomoses and tortuosity on oxygen transport.

Daniel Goldman;Aleksander S Popel

247
Citations
Computational fluid dynamic simulation of aggregation of deformable cells in a shear flow.

Prosenjit Bagchi;Paul C. Johnson;Aleksander S. Popel

246
Citations
Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle

Milos Cabel;Herbert J. Meiselman;Aleksander S. Popel;Paul C. Johnson;Paul C. Johnson

228
Citations
Reactive oxygen species regulate hypoxia-inducible factor 1α differentially in cancer and ischemia

Amina A. Qutub;Aleksander S. Popel

223
Citations