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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
21428
World Ranking
4548
National Ranking
2212

Research.com Recognitions

  • 2000 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Timothy W. Secomb is affiliated with the University of Arizona in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Radiology, Nuclear Medicine and Imaging, Molecular Biology, Cardiology and Cardiovascular Medicine, Cell Biology, and Neurology.

Their work addresses key topics including Traumatic Brain Injury and Neurovascular Disturbances, Angiogenesis and VEGF in Cancer, Hemoglobin Structure and Function, Nitric Oxide and Endothelin Effects, Advanced MRI Techniques and Applications, Coronary Interventions and Diagnostics, and Cardiovascular Health and Disease Prevention.

Frequent publication venues for their research include The FASEB Journal, Microcirculation, Physiology, Physiological Reports, and the Journal of Theoretical Biology.

Notable recent papers authored by or including Timothy W. Secomb are as follows:

  • Coalescent angiogenesis-evidence for a novel concept of vascular network maturation, 2021, Angiogenesis
  • Simulation of oxygen transport and estimation of tissue perfusion in extensive microvascular networks: Application to cerebral cortex, 2020, Journal of Cerebral Blood Flow & Metabolism
  • Effects of impaired microvascular flow regulation on metabolism-perfusion matching and organ function, 2020, Microcirculation
  • The Oxygen Cascade During Exercise in Health and Disease, 2021, Mayo Clinic Proceedings
  • Functional implications of microvascular heterogeneity for oxygen uptake and utilization, 2022, Physiological Reports

Timothy W. Secomb has collaborated frequently with several researchers, including Tuhin K. Roy, Michael J. Joyner, Sara Djurich, Grace V. Lee, and Chad C. Wiggins.

Award recognition includes being named a Fellow of the Indian National Academy of Engineering (INAE) in 2000.

Best Publications

  • The endothelial surface layer.

    A.R. Pries;T.W. Secomb;P. Gaehtgens

  • Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

    Stephen Lillioja;A Young;Carol L Culter;John L Ivy

  • Resistance to blood flow in microvessels in vivo.

    A R Pries;T W Secomb;T Gessner;M B Sperandio

  • Biophysical aspects of blood flow in the microvasculature

    A.R. Pries;T.W. Secomb;P. Gaehtgens

  • Transport of drugs from blood vessels to tumour tissue.

    Mark W. Dewhirst;Timothy W. Secomb

  • Blood flow in microvascular networks. Experiments and simulation.

    A R Pries;T W Secomb;P Gaehtgens;J F Gross

  • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.

    Hiroyuki Kimura;Rod D. Braun;Edgardo T. Ong;Richard Hsu

  • Microvascular blood viscosity in vivo and the endothelial surface layer.

    Axel R Pries;Tim W Secomb

  • Design principles of vascular beds.

    Axel R. Pries;Timothy W. Secomb;Peter Gaehtgens

  • Structural adaptation and stability of microvascular networks: theory and simulations

    A. R. Pries;T. W. Secomb;P. Gaehtgens

  • Causes and effects of heterogeneous perfusion in tumors.

    Robert J Gillies;Paul A Schornack;Timothy W Secomb;Natarajan Raghunand

  • Red Blood Cells and Other Nonspherical Capsules in Shear Flow: Oscillatory Dynamics and the Tank-Treading-to-Tumbling Transition

    J. M. Skotheim;T. W. Secomb

  • Flow of axisymmetric red blood cells in narrow capillaries

    T. W. Secomb;R. Skalak;N. Özkaya;J. F. Gross

  • Analysis of the Effects of Oxygen Supply and Demand on Hypoxic Fraction in Tumors

    Timothy W. Secomb;Richard Hsu;Edgardo T. Ong;Joseph F. Gross

  • The shunt problem: control of functional shunting in normal and tumour vasculature.

    Axel R. Pries;Michael Höpfner;Ferdinand le Noble;Mark W. Dewhirst

  • Blood Flow in the Microcirculation

    Timothy W. Secomb

  • Remodeling of Blood Vessels: Responses of Diameter and Wall Thickness to Hemodynamic and Metabolic Stimuli

    Axel R. Pries;Bettina Reglin;Timothy W. Secomb

  • Blood Flow in Microvascular Networks

    Axel R. Pries;Timothy W. Secomb

  • Rheology of the microcirculation.

    A. R. Pries;T. W. Secomb

  • Green's function methods for analysis of oxygen delivery to tissue by microvascular networks.

    Timothy W. Secomb;Richard Hsu;Eric Y. H. Park;Mark W. Dewhirst

Frequent Co-Authors

Mark W. Dewhirst
Mark W. Dewhirst Duke University
David A. Boas
David A. Boas Boston University
Richard Skalak
Richard Skalak Columbia University
Nicolas P. Smith
Nicolas P. Smith University of Auckland
Markus Sperandio
Markus Sperandio Ludwig-Maximilians-Universität München
William R. Wilson
William R. Wilson University of Auckland
Patrick Jenny
Patrick Jenny ETH Zurich
Bruno Weber
Bruno Weber University of Zurich
Anna Devor
Anna Devor Boston University

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