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Biology and Biochemistry

D-Index
69
Citations
17082
World Ranking
7385
National Ranking
572

Overview

Helen M. Byrne is affiliated with the University of Oxford in the United Kingdom. Their research integrates mathematical biology with computational and molecular approaches, focusing primarily on cancer biology and cellular dynamics.

The scientist's main fields of study include Biochemistry, Genetics and Molecular Biology, and Medicine. Key subfields encompass Molecular Biology, Modeling and Simulation, Oncology, Cell Biology, and Immunology.

Their research topics cover several areas, notably:

  • Mathematical Biology Tumor Growth
  • Single-cell and spatial transcriptomics
  • Gene Regulatory Network Analysis
  • Cancer Cells and Metastasis
  • Cellular Mechanics and Interactions
  • Cell Image Analysis Techniques
  • Topological and Geometric Data Analysis

Helen M. Byrne has contributed to multiple recent papers, including:

  • "A blood atlas of COVID-19 defines hallmarks of disease severity and specificity," 2022, published in Cell
  • "Mathematical modelling reveals cellular dynamics within tumour spheroids," 2020, published in PLoS Computational Biology
  • "Chaste: Cancer, Heart and Soft Tissue Environment," 2020, published in The Journal of Open Source Software
  • "Multiparameter persistent homology landscapes identify immune cell spatial patterns in tumors," 2021, published in Proceedings of the National Academy of Sciences
  • "Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer," 2021, published in Communications Biology

Their frequent co-authors include:

  • Philip K. Maini
  • Heather A. Harrington
  • Joshua A. Bull
  • Joe Pitt-Francis
  • Bernadette J. Stolz

Helen M. Byrne has published extensively in venues such as:

  • arXiv (Cornell University)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bulletin of Mathematical Biology
  • PLoS Computational Biology
  • Journal of Theoretical Biology

Best Publications

  • Reinforcement of hydrogels using three-dimensionally printed microfibres

    Jetze Visser;Ferry P W Melchels;June E Jeon;Erik M van Bussel

  • Modelling solid tumour growth using the theory of mixtures.

    Helen Byrne;Luigi Preziosi

  • A cellular automaton model for tumour growth in inhomogeneous environment

    T. Alarcón;H.M. Byrne;P.K. Maini

  • Growth of necrotic tumors in the presence and absence of inhibitors.

    H.M. Byrne;M.A.J. Chaplain

  • Dissecting cancer through mathematics: from the cell to the animal model.

    Helen M. Byrne

  • Individual-based and continuum models of growing cell populations: a comparison.

    Helen Byrne;Dirk Drasdo

  • Chaste: A test-driven approach to software development for biological modelling☆

    Joe Pitt-Francis;Pras Pathmanathan;Miguel O. Bernabeu;Rafel Bordas

  • Modelling aspects of cancer dynamics: a review.

    H.M Byrne;T Alarcon;M.R Owen;S.D Webb

  • A two-phase model of solid tumour growth

    H.M. Byrne;J.R. King;D.L.S. Mcelwain;Luigi Preziosi

  • Modelling the role of cell-cell adhesion in the growth and development of carcinomas

    H. M. Byrne;M. A. J. Chaplain

  • A Multiple Scale Model for Tumor Growth

    Tomas Alarcón;Helen M. Byrne;Philip K. Maini

  • Angiogenesis and vascular remodelling in normal and cancerous tissues

    Markus R. Owen;Tomás Alarcón;Philip K. Maini;Helen M. Byrne

  • A model of wound-healing angiogenesis in soft tissue

    G.J. Pettet;H.M. Byrne;D.L.S. Mcelwain;J. Norbury

  • Free boundary value problems associated with the growth and development of multicellular spheroids

    H. M. Byrne;M. A. J. Chaplain

  • A mathematical model to study the effects of drug resistance and vasculature on the response of solid tumors to chemotherapy

    Trachette L. Jackson;Helen M. Byrne

  • Mathematical models for tumour angiogenesis: numerical simulations and nonlinear wave solutions

    H. M. Byrne;M. A. J. Chaplain

  • The role of cell-cell interactions in a two-phase model for avascular tumour growth.

    C.J.W. Breward;H.M. Byrne;C.E. Lewis

  • Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions.

    Holger Perfahl;Helen M. Byrne;Tingan Chen;Veronica Estrella

  • The effect of time delays on the dynamics of avascular tumor growth

    H.M. Byrne

  • A multiphase model describing vascular tumour growth

    Christopher J. W. Breward;Helen M. Byrne;Claire E. Lewis

Frequent Co-Authors

Philip K. Maini
Philip K. Maini University of Oxford
Eamonn A. Gaffney
Eamonn A. Gaffney University of Oxford
Mark A. J. Chaplain
Mark A. J. Chaplain University of St Andrews
Claire E. Lewis
Claire E. Lewis University of Sheffield
Oliver E. Jensen
Oliver E. Jensen University of Manchester
Kevin M. Shakesheff
Kevin M. Shakesheff University of Nottingham
Alexander R. A. Anderson
Alexander R. A. Anderson Moffitt Cancer Center
Olaf Wolkenhauer
Olaf Wolkenhauer University of Rostock
Trevor Clive Dale
Trevor Clive Dale Cardiff University
Malcolm J. Bennett
Malcolm J. Bennett University of Nottingham

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