Masaharu Takigawa

Overview

Best Publications

• Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model.

  Toshifumi Mori;Shigeru Kawara;Mikio Shinozaki;Nobukazu Hayashi

  674
  Citations

• A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis

  Yoshinari Miyamoto;Akihiko Mabuchi;Dongquan Shi;Toshikazu Kubo

  607
  Citations

• Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo.

  Tsuyoshi Shimo;Tohru Nakanishi;Takashi Nishida;Masahiro Asano

  579
  Citations

• Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes

  Kazuhiro Sasaki;Takako Hattori;Takuo Fujisawa;Kojiro Takahashi

  387
  Citations

• Reduction in Connective Tissue Growth Factor by Antisense Treatment Ameliorates Renal Tubulointerstitial Fibrosis

  Hideki Yokoi;Masashi Mukoyama;Tetsuya Nagae;Kiyoshi Mori

  339
  Citations

• Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis.

  Shinichi Sato;Tetsuya Nagaoka;Minoru Hasegawa;Takuya Tamatani

  329
  Citations

• Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture.

  Tohru Nakanishi;Takashi Nishida;Tsuyoshi Shimo;Kappei Kobayashi

  327
  Citations

• Proposal for a unified CCN nomenclature

  D. R. Brigstock;R. Goldschmeding;K. I. Katsube;S. C.T. Lam

  289
  Citations

• Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal Fibrogenesis

  Hirokazu Okada;Tomohiro Kikuta;Tatsuya Kobayashi;Tsutomu Inoue

  281
  Citations

• Establishment of a Clonal Human Chondrosarcoma Cell Line with Cartilage Phenotypes

  Masaharu Takigawa;Koji Tajima;Hai Ou Pan;Motomi Enomoto

  279
  Citations

• Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro.

  Takashi Nishida;Tohru Nakanishi;Masahiro Asano;Tsuyoshi Shimo

  264
  Citations

• Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF.

  L H Pan;K Yamauchi;M Uzuki;T Nakanishi

  264
  Citations

• Cloning of a mRNA Preferentially Expressed in Chondrocytes by Differential Display-PCR from a Human Chondrocytic Cell Line That Is Identical with Connective Tissue Growth Factor (CTGF) mRNA

  Tohru Nakanishi;Yusuke Kimura;Tomoo Tamura;Hiroyuki Ichikawa

  263
  Citations

• Inhibition of Endogenous Expression of Connective Tissue Growth Factor by Its Antisense Oligonucleotide and Antisense RNA Suppresses Proliferation and Migration of Vascular Endothelial Cells

  Tsuyoshi Shimo;Tohru Nakanishi;Yusuke Kimura;Takashi Nishida

  257
  Citations

• Connective tissue growth factor increased by hypoxia may initiate angiogenesis in collaboration with matrix metalloproteinases

  Seiji Kondo;Satoshi Kubota;Tsuyoshi Shimo;Takashi Nishida

  248
  Citations

• Role of CTGF/HCS24/ecogenin in skeletal growth control

  Masaharu Takigawa;Tohru Nakanishi;Satoshi Kubota;Takashi Nishida

  246
  Citations

• Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1.

  Takuo Fujisawa;Takako Hattori;Kojiro Takahashi;Takuo Kuboki

  232
  Citations

• Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene

  Takanori Eguchi;Satoshi Kubota;Kazumi Kawata;Yoshiki Mukudai

  227
  Citations

• Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor).

  Takashi Nishida;Satoshi Kubota;Shunji Kojima;Takuo Kuboki

  219
  Citations

• CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen‐activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular‐signal regulated kinase (ERK)

  Gen Yosimichi;Tohru Nakanishi;Takashi Nishida;Takako Hattori

  216
  Citations