What is he best known for?
The fields of study he is best known for:
CTGF, Growth factor, Connective tissue, Internal medicine and Endocrinology are his primary areas of study.
His CTGF research is multidisciplinary, relying on both Fibrosis, Pathology, Molecular biology and Immunology.
His work deals with themes such as Cancer research, Angiogenesis, Vascular endothelial growth factor A and Extracellular matrix, Cell biology, which intersect with Growth factor.
Masaharu Takigawa interconnects Gene expression, Basic fibroblast growth factor, Messenger RNA and Cartilage, Endochondral ossification in the investigation of issues within Cell biology.
His study looks at the intersection of Internal medicine and topics like Immediate early protein with Dermatomyositis, Systemic disease and Gastroenterology.
His Endocrinology research is multidisciplinary, incorporating elements of Phenotype, Congenital muscular dystrophy, Parathyroid hormone and Ornithine decarboxylase.
His most cited work include:
- Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model. (406 citations)
- A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis (390 citations)
- Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. (361 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, CTGF, Molecular biology, Growth factor and Internal medicine.
His Cell biology research incorporates elements of Immunology and Chondrocyte, Cartilage, Endochondral ossification.
His study in CTGF is interdisciplinary in nature, drawing from both Extracellular matrix, Connective tissue, Regeneration, Fibrosis and Regulation of gene expression.
His Molecular biology research integrates issues from Cell culture, Messenger RNA, Gene expression, Northern blot and Monoclonal antibody.
As a member of one scientific family, Masaharu Takigawa mostly works in the field of Growth factor, focusing on Cancer research and, on occasion, Metastasis and Cancer cell.
As part of his studies on Internal medicine, he frequently links adjacent subjects like Endocrinology.
He most often published in these fields:
- Cell biology (39.51%)
- CTGF (31.36%)
- Molecular biology (28.89%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (39.51%)
- Growth factor (26.17%)
- CTGF (31.36%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Growth factor, CTGF, Cartilage and Molecular biology.
His Cell biology study combines topics in areas such as Chondrocyte, Cell culture and Endochondral ossification.
His work carried out in the field of Growth factor brings together such families of science as Endocrinology, Connective tissue and Fibroblast growth factor.
His biological study spans a wide range of topics, including Regulation of gene expression, Signal transduction and Matricellular protein.
The Cartilage study combines topics in areas such as Immunology, Pathology, Regeneration, Extracellular matrix and Genetically modified mouse.
His study on Molecular biology also encompasses disciplines like
- Gene expression and related In vitro,
- Gene and related Ccn family.
Between 2013 and 2021, his most popular works were:
- Cellular and molecular actions of CCN2/CTGF and its role under physiological and pathological conditions. (104 citations)
- Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver (66 citations)
- Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment. (57 citations)
In his most recent research, the most cited papers focused on:
Masaharu Takigawa focuses on Cell biology, Growth factor, Endocrinology, Internal medicine and Cancer research.
His Cell biology research includes themes of Chondrocyte, Cartilage, Endochondral ossification and Cellular differentiation.
Masaharu Takigawa combines subjects such as Extracellular matrix, Gene expression and Immunology with his study of Cartilage.
He is studying CTGF, which is a component of Growth factor.
As part of the same scientific family, Masaharu Takigawa usually focuses on CTGF, concentrating on Regulation of gene expression and intersecting with Extracellular.
His study in the field of Osteoprotegerin is also linked to topics like Macrophage colony-stimulating factor.
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