Bernard Perbal spends much of his time researching Cell biology, CTGF, CCN protein, Molecular biology and CYR61. His work deals with themes such as Dermis, Cell adhesion and Melanocyte, which intersect with Cell biology. As part of one scientific family, Bernard Perbal deals mainly with the area of CTGF, narrowing it down to issues related to the Transforming growth factor, and often Cell signaling, Hepatic stellate cell, Endogeny and Fibrosis.
His research investigates the link between CCN protein and topics such as CCN Intercellular Signaling Proteins that cross with problems in Sequence alignment, Function, Peptide sequence, Bone morphogenetic protein and Protein structure. His CYR61 study incorporates themes from Immediate early protein and Connective tissue. Bernard Perbal combines subjects such as Carcinogenesis and Pathology with his study of Immediate early protein.
Bernard Perbal mainly investigates Cell biology, Cancer research, Pathology, Molecular biology and Gene. His Cell biology research integrates issues from Endocrinology, Cell growth and CYR61, Growth factor, CTGF. His research integrates issues of Protein kinase B, Tyrosine kinase and MAP2K7, Protein kinase R, Cyclin-dependent kinase 2 in his study of Cancer research.
His work deals with themes such as Cancer, Extracellular matrix, Matricellular protein and Immediate early protein, which intersect with Pathology. The various areas that he examines in his Molecular biology study include Regulation of gene expression, Messenger RNA and Gene expression. His study in Gene is interdisciplinary in nature, drawing from both Kidney and Ccn family.
His primary areas of study are Pathology, Cell biology, Internal medicine, Endocrinology and Cancer research. His Pathology study combines topics from a wide range of disciplines, such as Extracellular matrix, Matricellular protein and Experimental pathology. His Cell biology research includes themes of Inflammation, Cell adhesion and Pseudopodia.
His Primary biliary cirrhosis, Hepatic stellate cell, Hepatic fibrosis and Tumor suppressor gene study in the realm of Internal medicine interacts with subjects such as Alcoholic liver disease. The Endocrinology study combines topics in areas such as Regulator, Downregulation and upregulation, CYR61, CTGF and Fibrosis. The concepts of his Cancer research study are interwoven with issues in Cancer and Bone marrow.
The scientist’s investigation covers issues in Internal medicine, Endocrinology, Cell biology, CTGF and Fibrosis. His study in the field of Osteoclast and Metastatic breast cancer is also linked to topics like Osteoprotegerin and RANKL. His Endocrinology study incorporates themes from Breast cancer, Breast disease, Hepatic fibrosis and Primary bone.
His Inflammation research extends to Cell biology, which is thematically connected. Particularly relevant to CYR61 is his body of work in CTGF. He focuses mostly in the field of Fibrosis, narrowing it down to matters related to Endogeny and, in some cases, Downregulation and upregulation, Diabetes mellitus, Diabetic nephropathy, Renal fibrosis and Kidney.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
CCN proteins: multifunctional signalling regulators.
The Lancet (2004)
NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues
Journal of Clinical Pathology-molecular Pathology (2001)
Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.
V Joliot;C Martinerie;G Dambrine;G Plassiart.
Molecular and Cellular Biology (1992)
Proposal for a unified CCN nomenclature
D. R. Brigstock;R. Goldschmeding;K. I. Katsube;S. C.T. Lam.
Journal of Clinical Pathology-molecular Pathology (2003)
The Nephroblastoma Overexpressed Gene (NOV/ccn3) Protein Associates with Notch1 Extracellular Domain and Inhibits Myoblast Differentiation via Notch Signaling Pathway
Kei Sakamoto;Shunji Yamaguchi;R. Ando;Atsushi Miyawaki.
Journal of Biological Chemistry (2002)
CCN3 (NOV) Interacts with Connexin43 in C6 Glioma Cells POSSIBLE MECHANISM OF CONNEXIN-MEDIATED GROWTH SUPPRESSION
Christine T. Fu;John F. Bechberger;Mark A. Ozog;Bernard Perbal.
Journal of Biological Chemistry (2004)
A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis
Nathalie Planque;Bernard Perbal.
Cancer Cell International (2003)
novH: differential expression in developing kidney and Wilm's tumors.
G. Chevalier;H. Yeger;C. Martinerie;M. Laurent.
American Journal of Pathology (1998)
Ccn Proteins: A New Family of Cell Growth and Differentiation Regulators
Bernard Perbal;Masaharu Takigawa.
Connexin43 Interacts with NOV A POSSIBLE MECHANISM FOR NEGATIVE REGULATION OF CELL GROWTH IN CHORIOCARCINOMA CELLS
Alexandra Gellhaus;Xuesen Dong;Sven Propson;Karen Maass.
Journal of Biological Chemistry (2004)
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