World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
85
Citations
27318
World Ranking
14577
National Ranking
203

Overview

Marta Ruiz-Ortega is affiliated with the Autonomous University of Madrid in Spain. Their research spans a range of topics primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Nephrology, Immunology, Pathology and Forensic Medicine, and Surgery.

The scientist's work focuses on several key areas, including Connective Tissue Growth Factor Research, Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, Acute Kidney Injury Research, Dialysis and Renal Disease Management, Phagocytosis and Immune Regulation, and Vitamin D Research Studies.

Among their recent publications are:

  • Targeting the progression of chronic kidney disease (2020, Nature Reviews Nephrology)
  • Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis (2021, Journal of Clinical Investigation)
  • Targeting inflammation to treat diabetic kidney disease: the road to 2030 (2022, Kidney International)
  • The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases (2020, Biomolecules)
  • Special Issue "Diabetic Nephropathy: Diagnosis, Prevention and Treatment" (2020, Journal of Clinical Medicine)

Frequent collaborators in their research include Alberto Ortíz, Sandra Rayego-Mateos, Raúl R. Rodrigues-Díez, Vanessa Marchant, and Lucía Tejedor-Santamaria.

Publication venues where this scientist has published most often include:

  • International Journal of Molecular Sciences
  • Journal of the American Society of Nephrology
  • Nephrology Dialysis Transplantation
  • Antioxidants
  • Kidney International

Best Publications

  • Inflammation and angiotensin II.

    Yusuke Suzuki;Marta Ruiz-Ortega;Oscar Lorenzo;Monica Ruperez

  • Angiotensin-Converting Enzyme Inhibition Prevents Arterial Nuclear Factor-κB Activation, Monocyte Chemoattractant Protein-1 Expression, and Macrophage Infiltration in a Rabbit Model of Early Accelerated Atherosclerosis

    M. Hernández-Presa;C. Bustos;M. Ortego;J. Tuñon

  • Angiotensin II and Renal Fibrosis

    Sergio A. Mezzano;Marta Ruiz-Ortega;Jesús Egido

  • TGF-β signaling in vascular fibrosis

    Marta Ruiz-Ortega;Juan Rodríguez-Vita;Elsa Sanchez-Lopez;Gisselle Carvajal

  • Targeting the progression of chronic kidney disease

    Marta Ruiz-Ortega;Sandra Rayego-Mateos;Santiago Lamas;Alberto Ortiz

  • NF-κB in Renal Inflammation

    Ana Belen Sanz;Maria Dolores Sanchez-Niño;Adrian Mario Ramos;Juan Antonio Moreno

  • Proinflammatory actions of angiotensins.

    Marta Ruiz-Ortega;Oscar Lorenzo;Yusuke Suzuki;Mónica Rupérez

  • Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney.

    Marta Ruiz-Ortega;Mónica Ruperez;Oscar Lorenzo;Vanesa Esteban

  • NF-κB activation and overexpression of regulated genes in human diabetic nephropathy

    Sergio Mezzano;Claudio Aros;Alejandra Droguett;M. Eugenia Burgos

  • Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases

    Marta Ruiz-Ortega;Mónica Rupérez;Vanesa Esteban;Juan Rodríguez-Vita

  • The Inflammatory Cytokines TWEAK and TNFα Reduce Renal Klotho Expression through NFκB

    Juan A. Moreno;Maria C. Izquierdo;Maria D. Sanchez-Niño;Beatriz Suárez-Alvarez

  • Angiotensin II Activates Nuclear Transcription Factor κB Through AT1 and AT2 in Vascular Smooth Muscle Cells Molecular Mechanisms

    Marta Ruiz-Ortega;Oscar Lorenzo;Mónica Rupérez;Sven König

  • Role of the Renin-Angiotensin System in Vascular Diseases: Expanding the Field

    M. Ruiz-Ortega;O. Lorenzo;M. Rupérez;V. Esteban

  • Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis.

    Marta Ruiz-Ortega;Carmen Bustos;Miguel A. Hernández-Presa;Oscar Lorenzo

  • Angiotensin II Activates the Smad Pathway in Vascular Smooth Muscle Cells by a Transforming Growth Factor-β–Independent Mechanism

    Juan Rodríguez-Vita;Elsa Sánchez-López;Vanesa Esteban;Mónica Rupérez

  • Tenofovir Nephrotoxicity: 2011 Update

    Beatriz Fernández-Fernández;Ana Montoya-Ferrer;Ana Belén Sanz;María Dolores Sánchez-Niño

  • Connective Tissue Growth Factor Is a Mediator of Angiotensin II–Induced Fibrosis

    Mónica Rupérez;Óscar Lorenzo;Luis Miguel Blanco-Colio;Vanesa Esteban

  • High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.

    Olha Zhenyukh;Esther Civantos;Marta Ruiz-Ortega;Maria Soledad Sánchez

  • Angiotensin II, via AT1 and AT2 Receptors and NF-κB Pathway, Regulates the Inflammatory Response in Unilateral Ureteral Obstruction

    Vanesa Esteban;Oscar Lorenzo;Mónica Rupérez;Yusuke Suzuki

  • Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibroblasts

    Marta Ruiz-Ortega;Jesús Egido

Frequent Co-Authors

Jesús Egido
Jesús Egido Autonomous University of Madrid
Alberto Ortiz
Alberto Ortiz Autonomous University of Madrid
Manuel López-Cabrera
Manuel López-Cabrera Spanish National Research Council
Carlos López-Larrea
Carlos López-Larrea Central University Hospital of Asturias
Santiago Lamas
Santiago Lamas Spanish National Research Council
Eliecer Coto
Eliecer Coto University of Oviedo
Roel Goldschmeding
Roel Goldschmeding Utrecht University
José M. López-Novoa
José M. López-Novoa University of Salamanca
György Kéri
György Kéri Semmelweis University
Victoria Alvarez
Victoria Alvarez University of Oviedo

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