World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
125
Citations
53422
World Ranking
3116
National Ranking
27

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

His primary areas of investigation include Internal medicine, Endocrinology, Fibrosis, Renal fibrosis and Cancer research. His Internal medicine research incorporates themes from Signal transduction and Cell biology. His biological study spans a wide range of topics, including Proinflammatory cytokine, Cytokine and MAPK/ERK pathway.

His Renal fibrosis research is multidisciplinary, relying on both Myofibroblast and Kidney metabolism. His work carried out in the field of Cancer research brings together such families of science as Downregulation and upregulation, microRNA, Metastasis, Genetic enhancement and Transforming growth factor beta. His study explores the link between Pathology and topics such as Glomerulonephritis that cross with problems in Immunology, Lupus nephritis, Macrophage and Proteinuria.

His most cited work include:

  • Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism (938 citations)
  • Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2 (583 citations)
  • Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro (429 citations)

What are the main themes of his work throughout his whole career to date?

Hui Y. Lan mostly deals with Internal medicine, Endocrinology, Immunology, Fibrosis and Glomerulonephritis. Receptor is closely connected to Signal transduction in his research, which is encompassed under the umbrella topic of Internal medicine. His Endocrinology study frequently draws connections between related disciplines such as Cell biology.

His study in Fibrosis is interdisciplinary in nature, drawing from both Inflammation and CTGF. Hui Y. Lan combines subjects such as Pathology, Basement membrane and Osteopontin with his study of Glomerulonephritis. Hui Y. Lan studied Kidney and Kidney disease that intersect with Nephrology and Nephropathy.

He most often published in these fields:

  • Internal medicine (56.94%)
  • Endocrinology (53.12%)
  • Immunology (25.00%)

What were the highlights of his more recent work (between 2011-2020)?

  • Internal medicine (56.94%)
  • Renal fibrosis (22.92%)
  • Endocrinology (53.12%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Internal medicine, Renal fibrosis, Endocrinology, Fibrosis and Cancer research. The various areas that Hui Y. Lan examines in his Internal medicine study include Diabetes mellitus, Type 2 diabetes and Gastroenterology. His Renal fibrosis research is multidisciplinary, incorporating perspectives in Transforming growth factor, Transforming growth factor beta, SMAD and microRNA.

His Endocrinology research is multidisciplinary, incorporating elements of Receptor and C-reactive protein. His studies deal with areas such as Inflammation, Downregulation and upregulation, Signal transduction and Kidney disease as well as Fibrosis. His Kidney disease research is multidisciplinary, incorporating perspectives in Immunology and Pharmacology.

Between 2011 and 2020, his most popular works were:

  • Inflammatory processes in renal fibrosis. (305 citations)
  • Role of the TGF-β/BMP-7/Smad pathways in renal diseases (221 citations)
  • miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice (202 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Hui Y. Lan spends much of his time researching Fibrosis, Renal fibrosis, Cancer research, Kidney and Transforming growth factor beta. His work deals with themes such as Downregulation and upregulation, Immunology and Kidney disease, which intersect with Fibrosis. His study in Renal fibrosis is interdisciplinary in nature, drawing from both Inflammation and Transforming growth factor.

Hui Y. Lan has researched Cancer research in several fields, including Endocrinology, Urokinase receptor, Internal medicine, CTGF and SMAD. The study incorporates disciplines such as Growth factor receptor and Cell growth in addition to Endocrinology. In his research on the topic of Internal medicine, Protein kinase B is strongly related with Diabetes mellitus.

Best Publications

  • TGF-β: the master regulator of fibrosis

    Xiao Ming Meng;David J. Nikolic-Paterson;Hui Yao Lan

  • Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism

    Marilda Mazzali;Jeremy Hughes;Yoon Goo Kim;J. Ashley Jefferson

  • Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism

    Marilda Mazzali;John Kanellis;Lin Han;Lili Feng

  • Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2

    John Kanellis;Susumu Watanabe;Jinhua Li;Duk Hee Kang

  • Uric Acid, Hominoid Evolution, and the Pathogenesis of Salt-Sensitivity

    Susumu Watanabe;Duk Hee Kang;Lili Feng;Takahiko Nakagawa

  • Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro

    Jun-Ming Fan;Yee-Yung Ng;Prudence A. Hill;David J. Nikolic-Paterson

  • Diverse roles of TGF-β/Smads in renal fibrosis and inflammation.

    Hui Yao Lan

  • Macrophages: versatile players in renal inflammation and fibrosis

    Patrick Ming Kuen Tang;David J. Nikolic-Paterson;Hui Yao Lan

  • Renal tubule injury: a driving force toward chronic kidney disease.

    Bi-Cheng Liu;Tao-Tao Tang;Lin-Li Lv;Hui-Yao Lan

  • TGF-β/Smad signaling in renal fibrosis

    Xiao-Ming Meng;Patrick Ming-Kuen Tang;Jun Li;Hui Yao Lan

  • Inflammatory processes in renal fibrosis.

    Xiao-Ming Meng;David J Nikolic-Paterson;Hui Yao Lan

  • TGF-β/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

    Wei Qin;Arthur C.K. Chung;Xiao R. Huang;Xiao-Ming Meng

  • A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer

    Roberta Pang;Wai Lun Law;Andrew C.Y. Chu;Jensen T. Poon

  • Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats

    Yee-Yung Ng;Tung-Po Huang;Tung-Po Huang;Wu-Chang Yang;Wu-Chang Yang;Zheng-Ping Chen;Zheng-Ping Chen

  • Transforming growth factor-beta and Smad signalling in kidney diseases.

    Wansheng Wang;Vijay Koka;Hui Y Lan

  • Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis

    Xiang Zhong;Arthur Chi Kong Chung;Hai-Yong Chen;Xiaoming Meng

  • Inhibition of Renal Fibrosis by Gene Transfer of Inducible Smad7 Using Ultrasound-Microbubble System in Rat UUO Model

    Hui Y Lan;Wei Mu;Naruya Tomita;Xiao R Huang

  • Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation.

    Jinhua Li;Hong-Jian Zhu;Xiao R Huang;Kar N Lai

  • miR-192 Mediates TGF-β/Smad3-Driven Renal Fibrosis

    Arthur C.K. Chung;Xiao R. Huang;Xiaoming Meng;Hui Y. Lan

  • Role of the TGF-β/BMP-7/Smad pathways in renal diseases

    Xiao-Ming Meng;Arthur C. K. Chung;Hui Y. Lan

Frequent Co-Authors

David J. Nikolic-Paterson
David J. Nikolic-Paterson Monash Medical Centre
Robert C. Atkins
Robert C. Atkins Monash Medical Centre
Richard Bucala
Richard Bucala Yale University
Richard J. Johnson
Richard J. Johnson University of Colorado Denver
Christine N. Metz
Christine N. Metz Feinstein Institute for Medical Research
Benjamin C.Y. Wong
Benjamin C.Y. Wong University of Hong Kong
Joseph Leung
Joseph Leung University of California, Davis
Liang Qiao
Liang Qiao University of Sydney
Luan D. Truong
Luan D. Truong Cornell University
Alexander J. Szalai
Alexander J. Szalai University of Alabama at Birmingham

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