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Immunology
USA
2026

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Immunology

D-Index
148
Citations
82140
World Ranking
128
National Ranking
84

Medicine

D-Index
149
Citations
84296
World Ranking
1200
National Ranking
691

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award

Overview

Richard Bucala is a researcher affiliated with Yale University in the United States. Their work primarily focuses on immunology and microbiology, contributing substantially to the fields of neuroscience, rheumatology, pharmacology, and oncology.

They have published extensively on topics that include macrophage migration inhibitory factor, nuclear receptors and signaling, galectins and cancer biology, apelin-related biomedical research, systemic lupus erythematosus research, cytokine signaling pathways and interactions, and the role of immune cells in cancer.

Frequent coauthors in Bucala's research include Lin Leng, Thuy Tran, Gabriela Athziri Sánchez-Zuno, Caroline Naomi Valdez, and Lais Osmani.

Their publications appear regularly in venues such as:

  • PLoS Biology
  • Regular and Young Investigator Award Abstracts
  • The Journal of Urology
  • Frontiers in Immunology
  • Cell Reports

Selected recent papers by Richard Bucala are:

  • "Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression", 2020, Frontiers in Immunology
  • "CD74 as a regulator of transcription in normal B cells", 2022, Cell Reports
  • "CD74 is a regulator of hematopoietic stem cell maintenance", 2021, PLoS Biology
  • "CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells", 2024, PLoS Biology
  • "Potential role of RhoA GTPase regulation in type interferon signaling in systemic lupus erythematosus", 2024, Arthritis Research & Therapy

Best Publications

  • Regulation of lung injury and repair by Toll-like receptors and hyaluronan.

    Dianhua Jiang;Jiurong Liang;Juan Fan;Shuang Yu

  • Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair.

    Richard Bucala;Lori A. Spiegel;Jason Chesney;Margaret Hogan

  • Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

    R Bucala;K J Tracey;A Cerami

  • MIF as a glucocorticoid-induced modulator of cytokine production

    Thierry Calandra;Jürgen Bernhagen;Christine N. Metz;Lori A. Spiegel

  • MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

    Jürgen Bernhagen;Regina Krohn;Hongqi Lue;Julia L Gregory

  • Peripheral blood fibrocytes differentiation pathway and migration to wound sites

    Riichiro Abe;Richard Bucala;Seamas Donnelly;Christine Metz

  • MIF signal transduction initiated by binding to CD74.

    Lin Leng;Christine N. Metz;Yan Ju Fang;Jing-Jing Xu

  • MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia

    J. Bernhagen;T. Calandra;R. A. Mitchell;S. B. Martin

  • The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor.

    Thierry Calandra;JLirgen Bernhagen;Robert A. Mitchell;Richard Bucala

  • Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

    Vlassara H;Bucala R;Striker L

  • Advanced glycation end products contribute to amyloidosis in Alzheimer disease

    M. P. Vitek;Keshab Bhattacharya;J. M. Glendening;E. Stopa

  • Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy.

    Theodore Koschinsky;Ci-Jiang He;Tomoko Mitsuhashi;Richard Bucala

  • Protection from septic shock by neutralization of macrophage migration inhibitory factor.

    Thierry Calandra;Bernd Echtenacher;Didier Le Roy;Jérôme Pugin

  • An essential regulatory role for macrophage migration inhibitory factor in T-cell activation

    Michael Bacher;Christine N. Metz;Thierry Calandra;Katrin Mayer

  • Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

    Wibke Schulte;Jürgen Bernhagen;Richard Bucala

  • Lipid advanced glycosylation : pathway for lipid oxidation in vivo

    Richard Bucala;Zenji Makita;Theodor Koschinsky;Anthony Cerami

  • Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response

    Robert A. Mitchell;Hong Liao;Jason Chesney;Gunter Fingerle-Rowson

  • CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.

    Xuerong Shi;Lin Leng;Tian Wang;Wenkui Wang

  • Tobacco Smoke is a Source of Toxic Reactive Glycation Products

    Carla Cerami;Hank Founds;Iain Nicholl;Tomoko Mitsuhashi

  • Immunochemical detection of advanced glycosylation end products in vivo.

    Z Makita;H Vlassara;A Cerami;R Bucala

Frequent Co-Authors

Lin Leng
Lin Leng Yale University
Christine N. Metz
Christine N. Metz Feinstein Institute for Medical Research
Jürgen Bernhagen
Jürgen Bernhagen Ludwig-Maximilians-Universität München
Anthony Cerami
Anthony Cerami Araim Pharmaceuticals (United States)
Elias Lolis
Elias Lolis Yale University
Thierry Calandra
Thierry Calandra University of Lausanne
Hui Y. Lan
Hui Y. Lan Chinese University of Hong Kong
Jason Chesney
Jason Chesney University of Louisville
Eric F. Morand
Eric F. Morand Monash University
Andreas Meinhardt
Andreas Meinhardt University of Giessen

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