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Immunology

D-Index
93
Citations
33237
World Ranking
964
National Ranking
531

Medicine

D-Index
93
Citations
33515
World Ranking
10845
National Ranking
5582

Overview

Christine N. Metz is affiliated with the Feinstein Institute for Medical Research in the United States. Their primary research area falls within the field of Medicine, with substantial contributions to subfields such as Neurology, Immunology, Obstetrics and Gynecology, Infectious Diseases, and Reproductive Medicine.

Their scholarly work covers several main topics, including:

  • Reproductive System and Pregnancy
  • Endometriosis Research and Treatment
  • Vagus Nerve Stimulation Research
  • COVID-19 Clinical Research Studies
  • Uterine Myomas and Treatments
  • Nicotinic Acetylcholine Receptors Study
  • SARS-CoV-2 and COVID-19 Research

Christine N. Metz has published several notable papers in recent years. Selected examples include:

  • "Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths" (2021) in Science Immunology
  • "Menstruation: science and society" (2020) in American Journal of Obstetrics and Gynecology
  • "The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies" (2022) in Proceedings of the National Academy of Sciences
  • "Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis" (2022) in BMC Medicine
  • "Histopathologic evaluation of placentas after diagnosis of maternal severe acute respiratory syndrome coronavirus 2 infection" (2020) in American Journal of Obstetrics & Gynecology MFM

Their frequent coauthors include:

  • Peter K. Gregersen
  • Prodyot K. Chatterjee
  • Kevin J. Tracey
  • Valentin A. Pavlov
  • Andrew Shih

The most common publication venues for their work are:

  • American Journal of Obstetrics and Gynecology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Angiology
  • Frontiers in Immunology
  • Scientific Reports

Best Publications

  • MIF as a glucocorticoid-induced modulator of cytokine production

    Thierry Calandra;Jürgen Bernhagen;Christine N. Metz;Lori A. Spiegel

  • Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.

    Hong Wang;Hong Liao;Mahendar Ochani;Marilou Justiniani

  • Peripheral blood fibrocytes differentiation pathway and migration to wound sites

    Riichiro Abe;Richard Bucala;Seamas Donnelly;Christine Metz

  • MIF signal transduction initiated by binding to CD74.

    Lin Leng;Christine N. Metz;Yan Ju Fang;Jing-Jing Xu

  • Protection from septic shock by neutralization of macrophage migration inhibitory factor.

    Thierry Calandra;Bernd Echtenacher;Didier Le Roy;Jérôme Pugin

  • An essential regulatory role for macrophage migration inhibitory factor in T-cell activation

    Michael Bacher;Christine N. Metz;Thierry Calandra;Katrin Mayer

  • Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action.

    Robert A. Mitchell;Christine N. Metz;Tina Peng;Richard Bucala

  • Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation

    Rubina W. Saeed;Santosh Varma;Tina Peng-Nemeroff;Barbara Sherry

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • REGULATORY ROLE FOR MACROPHAGE MIGRATION INHIBITORY FACTOR IN ACUTE RESPIRATORY DISTRESS SYNDROME

    Seamas C. Donnelly;Chris Haslett;Peter T. Reid;Ian S. Grant

  • Advanced Glycation End Products and Endothelial Dysfunction in Type 2 Diabetes

    Kathryn C.B. Tan;Wing-Sun Chow;Victor H.G. Ai;Christine Metz

  • Regulated Production of Type I Collagen and Inflammatory Cytokines by Peripheral Blood Fibrocytes

    Jason Chesney;Christine Metz;Abram B. Stavitsky;Michael Bacher

  • The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.

    Evald Rosengren;Richard Bucala;Pierre Åman;Lars Jacobsson

  • Macrophage migration inhibitory factor in rheumatoid arthritis: Evidence of proinflammatory function and regulation by glucocorticoids

    Michelle Leech;Christine N Metz;Pamela Hall;Paul Hutchinson

  • An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma

    Jason Chesney;Christine Metz;Michael Bacher;Tina Peng

  • High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers.

    Toshiya Atsumi;Jason Chesney;Christine Metz;Lin Leng

  • Menstruation: science and society

    Hilary O.D. Critchley;Elnur Babayev;Serdar E. Bulun;Sandy Clark

  • Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo

    Ingo Hartlapp;Riichiro Abe;Rubina W. Saeed;Tina Peng

  • ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis

    Yousef Al-Abed;Darrin Dabideen;Bayan Aljabari;Aline Valster

  • Migration inhibitory factor expression in experimentally induced endotoxemia.

    M. Bacher;A. Meinhardt;H. Y. Lan;W. Mu

  • The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat

    Hui Y. Lan;Michael Bacher;Niansheng Yang;Wei Mu

Frequent Co-Authors

Richard Bucala
Richard Bucala Yale University
Kevin J. Tracey
Kevin J. Tracey Feinstein Institute for Medical Research
Valentin A. Pavlov
Valentin A. Pavlov Feinstein Institute for Medical Research
Andreas Meinhardt
Andreas Meinhardt University of Giessen
Robert C. Atkins
Robert C. Atkins Monash Medical Centre
Hui Y. Lan
Hui Y. Lan Chinese University of Hong Kong
David J. Nikolic-Paterson
David J. Nikolic-Paterson Monash Medical Centre
Thierry Calandra
Thierry Calandra University of Lausanne
Riichiro Abe
Riichiro Abe Niigata University
Jason Chesney
Jason Chesney University of Louisville

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