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Immunology

D-Index
60
Citations
14841
World Ranking
3308
National Ranking
79

Overview

Thierry Roger is affiliated with the University of Lausanne in Switzerland. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine, with a considerable focus on Immunology subfields. They have contributed to various subfields including Immunology, Epidemiology, Molecular Biology, Obstetrics and Gynecology, and Infectious Diseases.

Themes central to their work involve:

  • Immune Response and Inflammation
  • Sepsis Diagnosis and Treatment
  • Immune responses and vaccinations
  • Inflammation biomarkers and pathways
  • Immune cells in cancer
  • COVID-19 Impact on Reproduction
  • Vaccine Coverage and Hesitancy

Their publication history includes articles in notable venues such as:

  • Frontiers in Immunology
  • Nature Immunology
  • Critical Care
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers authored or co-authored by Thierry Roger include:

  • Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality, 2020, Science Advances
  • Transmission of trained immunity and heterologous resistance to infections across generations, 2021, Nature Immunology
  • The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients, 2021, Nature Communications
  • Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway, 2021, The FASEB Journal
  • Modes of action and diagnostic value of miRNAs in sepsis, 2022, Frontiers in Immunology

Frequent collaborators include:

  • Didier Le Roy
  • Evangelos J. Giamarellos-Bourboulis
  • Thierry Calandra
  • Irene T. Schrijver
  • Mihai G. Netea

In addition to research articles, Thierry Roger has contributed to academic book publications with titles such as:

  • Spectres de Mallarmé, published by Hermann eBooks in 2021
  • Le poète et le joueur de quilles. Enquête sur la construction de la valeur de la poésie (XIVe-XXIe siècle), published by Centre National de la Recherche Scientifique in 2023

Best Publications

  • Macrophage migration inhibitory factor: a regulator of innate immunity.

    Thierry Calandra;Thierry Roger

  • MIF regulates innate immune responses through modulation of Toll-like receptor 4

    Thierry Roger;John David;Michel P. Glauser;Thierry Calandra

  • Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

    Robert Kleemann;Angelika Hausser;Georg Geiger;Ralf Mischke

  • Initial responses to endotoxins and Gram-negative bacteria.

    Didier Heumann;Thierry Roger

  • Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease.

    Hongqi Lue;Robert Kleemann;Thierry Calandra;Thierry Roger

  • Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4

    Thierry Roger;Céline Froidevaux;Didier Le Roy;Marlies Knaup Reymond

  • Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

    Julie Delaloye;Thierry Roger;Quynh-Giao Steiner-Tardivel;Didier Le Roy

  • Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

    Thierry Roger;Jérôme Lugrin;Didier Le Roy;Geneviève Goy

  • Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases

    Athina Savva;Thierry Roger

  • Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1β Secretion through the NLRP3 Inflammasome In Vitro

    Borbála Pazár;Hang-Korng Ea;Hang-Korng Ea;Sharmal Narayan;Laeticia Kolly

  • Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.

    Hongqi Lue;Aphrodite Kapurniotu;Günter Fingerle-Rowson;Thierry Roger

  • Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation

    Annette Ives;Johji Nomura;Fabio Martinon;Thierry Roger

  • Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1.

    Thierry Roger;Anne Laure Chanson;Marlies Knaup-Reymond;Thierry Calandra

  • IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction

    Stéphanie Bibert;Thierry Roger;Thierry Calandra;Murielle Bochud

  • Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality

    Benjamin Demarco;James P. Grayczyk;Elisabet Bjanes;Didier Le Roy

  • Myeloid-Derived Suppressor Cells in Sepsis.

    Irene T. Schrijver;Charlotte Théroude;Thierry Roger

  • T H 17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

    Stephan Meller;Stephan Meller;Jeremy Di Domizio;Kui Shin Voo;Heike C. Friedrich

  • Enhanced AP-1 and NF-kappaB activities and stability of interleukin 8 (IL-8) transcripts are implicated in IL-8 mRNA superinduction in lung epithelial H292 cells.

    Thierry Roger;A. Theo Out;Naofumi Mukaida;Kouji Matsushima

  • Macrophage Migration Inhibitory Factor: Gene Polymorphisms and Susceptibility to Inflammatory Diseases

    Pascal Renner;Thierry Roger;Thierry Calandra

  • Regulation of human lung adenocarcinoma cell migration and invasion by macrophage migration inhibitory factor.

    Beatriz E. Rendon;Thierry Roger;Ivo Teneng;Ming Zhao

Frequent Co-Authors

Thierry Calandra
Thierry Calandra University of Lausanne
Giuseppe Pantaleo
Giuseppe Pantaleo University of Lausanne
Mariano Esteban
Mariano Esteban Spanish National Research Council
René Lutter
René Lutter University of Amsterdam
Henk M. Jansen
Henk M. Jansen University of Amsterdam
Alexandre Harari
Alexandre Harari University of Lausanne
Fred C.G.J. Sweep
Fred C.G.J. Sweep Radboud University
Jürgen Bernhagen
Jürgen Bernhagen Ludwig-Maximilians-Universität München
Pierre-Yves Bochud
Pierre-Yves Bochud University of Lausanne
Gilbert Greub
Gilbert Greub University of Lausanne

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