Thierry Roger spends much of his time researching Cytokine, Innate immune system, Macrophage migration inhibitory factor, Immunology and Immune system. Internal medicine covers Thierry Roger research in Cytokine. His Innate immune system study focuses mostly on Toll-like receptor and TLR2.
His biological study spans a wide range of topics, including Cancer research, Inflammation and Kinase, MAPK/ERK pathway, Cell biology. His Immunology study integrates concerns from other disciplines, such as Genome-wide association study, Virology and Pathology. His research integrates issues of Lipopolysaccharide and Pathogenesis in his study of Immune system.
Thierry Roger focuses on Immunology, Innate immune system, Macrophage migration inhibitory factor, Cytokine and Immune system. His study in Immunology focuses on Sepsis, Inflammation, Tumor necrosis factor alpha, Immunity and Antigen. His Innate immune system research includes themes of Macrophage, Microbiology and TLR4.
His Macrophage migration inhibitory factor study combines topics from a wide range of disciplines, such as Molecular biology, Cancer research, Endocrinology and Cell biology. In his research, In vitro is intimately related to Proinflammatory cytokine, which falls under the overarching field of Cytokine. His Immune system research is multidisciplinary, incorporating elements of Antibody and Virology.
Innate immune system, Immunology, Cytokine, Immune system and Inflammation are his primary areas of study. His work deals with themes such as Cell culture, Cell, In vitro, Macrophage and Staphylococcus aureus, which intersect with Innate immune system. His Immunology research focuses on Coronavirus disease 2019 and how it connects with Fibrosis and Immune defence.
His biological study focuses on Macrophage migration inhibitory factor. His Macrophage migration inhibitory factor research incorporates themes from Endocrinology, Developmental profile and Neonatal sepsis. His Immune system research is multidisciplinary, incorporating perspectives in Internal medicine, Knockout mouse and Interleukin 8.
His primary scientific interests are in Immunology, Innate immune system, Immune system, Cytokine and Sepsis. His Innate immune system research includes elements of Inflammation and Polysaccharide. The various areas that Thierry Roger examines in his Immune system study include Cell metabolism, In vitro, Knockout mouse and Pneumonia.
His biological study deals with issues like Microbiology, which deal with fields such as Staphylococcus aureus and Propionate. His Sepsis research is multidisciplinary, relying on both Macrophage migration inhibitory factor and Pathogenesis. His research investigates the connection between Tumor necrosis factor alpha and topics such as Cell biology that intersect with issues in Toll-like receptor.
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Macrophage migration inhibitory factor: a regulator of innate immunity.
Thierry Calandra;Thierry Roger.
Nature Reviews Immunology (2003)
MIF regulates innate immune responses through modulation of Toll-like receptor 4
Thierry Roger;John David;Michel P. Glauser;Thierry Calandra.
Nature (2001)
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
Robert Kleemann;Angelika Hausser;Georg Geiger;Ralf Mischke.
Nature (2000)
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease.
Hongqi Lue;Robert Kleemann;Thierry Calandra;Thierry Roger.
Microbes and Infection (2002)
Initial responses to endotoxins and Gram-negative bacteria.
Didier Heumann;Thierry Roger.
Clinica Chimica Acta (2002)
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.
Julie Delaloye;Thierry Roger;Quynh-Giao Steiner-Tardivel;Didier Le Roy.
PLOS Pathogens (2009)
Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4
Thierry Roger;Céline Froidevaux;Didier Le Roy;Marlies Knaup Reymond.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
Thierry Roger;Jérôme Lugrin;Didier Le Roy;Geneviève Goy.
Blood (2011)
Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases
Athina Savva;Thierry Roger.
Frontiers in Immunology (2013)
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.
Hongqi Lue;Aphrodite Kapurniotu;Günter Fingerle-Rowson;Thierry Roger.
Cellular Signalling (2006)
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