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Biology and Biochemistry

D-Index
63
Citations
37889
World Ranking
9949
National Ranking
4355

Overview

Jason Chesney is a researcher affiliated with the University of Louisville in the United States, focusing on oncology, immunology, molecular biology, genetics, and biotechnology. Their work primarily addresses cancer immunotherapy, molecular pathways of cancer, virus-based gene therapy, and immune responses related to cancer treatment.

Their research interests cover several prominent topics, including:

  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Virus-based gene therapy research
  • Cancer Research and Treatments
  • Cancer-related Molecular Pathways
  • Cancer, Hypoxia, and Metabolism

Jason Chesney has contributed extensively to scientific literature, with a concentration in fields such as medicine and biochemistry, genetics, and molecular biology. The subfields they specialize in include oncology, immunology, molecular biology, genetics, and biotechnology.

The following recent papers illustrate the focus and scope of their work:

  • Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma, 2021, Journal of Clinical Oncology
  • Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint inhibitors and targeted therapies: pooled analysis of consecutive cohorts of the C-144-01 study, 2022, Journal for ImmunoTherapy of Cancer
  • Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma, 2022, Journal of Clinical Oncology
  • Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study, 2020, Clinical Cancer Research
  • Talimogene laherparepvec in combination with ipilimumab versus ipilimumab alone for advanced melanoma: 5-year final analysis of a multicenter, randomized, open-label, phase II trial, 2023, Journal for ImmunoTherapy of Cancer

The researcher frequently publishes in several key venues widely recognized in oncology and cancer research. These include:

  • Journal of Clinical Oncology
  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Annals of Oncology
  • Journal for ImmunoTherapy of Cancer

Jason Chesney collaborates regularly with a group of coauthors, reflecting an active network in the oncology and immunotherapy research community. Frequent collaborators include:

  • Sajeve Thomas
  • Omid Hamid
  • Theresa Medina
  • Mohammed Milhem
  • Amod A. Sarnaik

This profile reflects Jason Chesney's contributions to cancer immunotherapy and related biomedical fields, highlighting a research agenda centered on innovative therapy development and clinical trial investigation.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Nivolumab and ipilimumab versus ipilimumab in untreated melanoma

    Michael A. Postow;Jason Chesney;Anna C. Pavlick;Caroline Robert

  • Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

    Robert H.I. Andtbacka;Howard L. Kaufman;Frances Collichio;Thomas Amatruda

  • Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair.

    Richard Bucala;Lori A. Spiegel;Jason Chesney;Margaret Hogan

  • Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

    Katrien De Bock;Maria Georgiadou;Sandra Schoors;Anna Kuchnio

  • Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

    Jedd D Wolchok;Bart Neyns;Gerald Linette;Sylvie Negrier

  • Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial

    F Stephen Hodi;Jason Chesney;Anna C Pavlick;Caroline Robert

  • An essential regulatory role for macrophage migration inhibitory factor in T-cell activation

    Michael Bacher;Christine N. Metz;Thierry Calandra;Katrin Mayer

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response

    Robert A. Mitchell;Hong Liao;Jason Chesney;Gunter Fingerle-Rowson

  • Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma

    Jason Chesney;Igor Puzanov;Frances Collichio;Parminder Singh

  • Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

    Sandra Schoors;Katrien De Bock;Anna Rita Cantelmo;Maria Georgiadou

  • First-Line Nivolumab Plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers.

    Neal Ready;Matthew D. Hellmann;Mark M. Awad;Gregory A. Otterson

  • MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma

    Scott J. Rodig;Scott J. Rodig;Daniel Gusenleitner;Donald G. Jackson;Evisa Gjini

  • Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials.

    Dirk Schadendorf;Jedd D. Wolchok;F. Stephen Hodi;Vanna Chiarion-Sileni

  • Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

    Brian Clem;Sucheta Telang;Amy Clem;Abdullah Yalcin

  • Regulated Production of Type I Collagen and Inflammatory Cytokines by Peripheral Blood Fibrocytes

    Jason Chesney;Christine Metz;Abram B. Stavitsky;Michael Bacher

  • Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

    Abdullah Yalcin;Sucheta Telang;Brian Clem;Jason Chesney

  • The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ

    Jason Chesney;Michael Bacher;Armin Bender;Richard Bucala

  • An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma

    Jason Chesney;Christine Metz;Michael Bacher;Tina Peng

Frequent Co-Authors

Richard Bucala
Richard Bucala Yale University
John O. Trent
John O. Trent University of Louisville
Michael A. Postow
Michael A. Postow Memorial Sloan Kettering Cancer Center
Omid Hamid
Omid Hamid Cedars-Sinai Medical Center
Igor Puzanov
Igor Puzanov Roswell Park Cancer Institute
Merrick I. Ross
Merrick I. Ross The University of Texas MD Anderson Cancer Center
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
John M. Kirkwood
John M. Kirkwood University of Pittsburgh
Howard L. Kaufman
Howard L. Kaufman Harvard University
Kevin J. Harrington
Kevin J. Harrington Royal Marsden NHS Foundation Trust

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