World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
7666
World Ranking
19280
National Ranking
449

Overview

Jos L. V. Broers is affiliated with Maastricht University in the Netherlands and has contributed to research primarily within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several subfields, notably Molecular Biology, Cell Biology, Oncology, Epidemiology, and Cardiology and Cardiovascular Medicine.

The scientist's research has focused on topics including Nuclear Structure and Function, RNA Research and Splicing, Skin and Cellular Biology Research, Cancer Cells and Metastasis, Cervical Cancer and HPV Research, RNA Interference and Gene Delivery, and Cellular Transport and Secretion.

Frequent co-authors in their publications include Frans C. S. Ramaekers, Merel Stiekema, Marc A. M. J. van Zandvoort, Jobran M. Moshi, and Monique Ummelen.

The scientist has published in various journals, with several papers appearing in Histochemistry and Cell Biology, as well as in Cells, the International Journal of Molecular Sciences, Frontiers in Cell and Developmental Biology, and Circulation Genomic and Precision Medicine.

Recent publications include the following:

  • Structural and Mechanical Aberrations of the Nuclear Lamina in Disease, 2020, Cells
  • Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures, 2021, International Journal of Molecular Sciences
  • The Role of Lamins in the Nucleoplasmic Reticulum, a Pleiomorphic Organelle That Enhances Nucleo-Cytoplasmic Interplay, 2022, Frontiers in Cell and Developmental Biology
  • Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy, 2023, Circulation Genomic and Precision Medicine
  • Impact of antigen retrieval protocols on the immunohistochemical detection of epigenetic DNA modifications, 2023, Histochemistry and Cell Biology

Best Publications

  • Nuclear lamins: laminopathies and their role in premature ageing

    J. L. V. Broers;F. C. S. Ramaekers;G. Bonne;R. Ben Yaou

  • Decreased mechanical stiffness in LMNA−/− cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies

    Jos L.V. Broers;Emiel A.G. Peeters;Helma J.H. Kuijpers;Jorike Endert

  • Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins

    J.L.V. Broers;B.M. Machiels;G.J.J.M. van Eys;H.J.H. Kuijpers

  • Cytokeratins in Different Types of Human Lung Cancer as Monitored by Chain-specific Monoclonal Antibodies

    J. L. V. Broers;F. C. S. Ramaekers;M. K. Rot;T. Oostendorp

  • The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus.

    Ewa Markiewicz;Katarzyna Tilgner;Nick Barker;Mark van de Wetering

  • Both emerin and lamin C depend on lamin A for localization at the nuclear envelope.

    O.A. Vaughan;M. Alvarez-Reyes;J.M. Bridger;J.L.V. Broers

  • An alternative splicing product of the lamin A/C gene lacks exon 10

    Barbie M. Machiels;Antoine H.G. Zorenc;Jorike M. Endert;Helma J.H. Kuijpers

  • Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies

    Winnok H. De Vos;Frederik Houben;Miriam Kamps;Ashraf Malhas

  • A- and B-type lamins are differentially expressed in normal human tissues.

    J. L. V. Broers;Barbie M. Machiels;Helma J. H. Kuijpers;Frank Smedts

  • A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors.

    J.H. Van Berlo;J.W. Voncken;N. Kubben;J.L.V. Broers

  • Nuclear A-type lamins are differentially expressed in human lung cancer subtypes.

    J. L. V. Broers;Y. Raymond;M. K. Rot;H. Kuijpers

  • Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies.

    J. L. V. Broers;D. N. Carney;M. Klein Rot;G. Schaart

  • Electric Discharge Plasmas Influence Attachment of Cultured CHO K1 Cells

    I.E. Kieft;J.L.V. Broers;J.L.V. Broers;V. Caubet-Hilloutou;D.W. Slaaf;D.W. Slaaf

  • Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

    Vanja Pekovic;Jens Harborth;Jos L.V. Broers;Frans C.S. Ramaekers

  • Effects of ethanol and acetaldehyde on tight junction integrity: in vitro study in a three dimensional intestinal epithelial cell culture model.

    Elhaseen Elamin;Daisy Jonkers;Kati Juuti-Uusitalo;Sven van IJzendoorn

  • Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization

    J. L V Broers;S. M. Jensen;W. D. Travis;H. Pass

  • Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formation.

    Christelle Lecut;Anne Schoolmeester;Marijke J.E. Kuijpers;Jos L.V. Broers

  • Lamin expression in normal human skin, actinic keratosis, squamous cell carcinoma and basal cell carcinoma

    C.M.L.J. Tilli;F.C.S. Ramaekers;J.L.V. Broers;C.J. Hutchison

  • Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation

    Valerie L.R.M. Verstraeten;Jos L.V. Broers;Maurice A.M. van Steensel;Sophie Zinn-Justin

  • The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion

    Yvonne K. Gruijthuijsen;Paola Casarosa;Suzanne J. F. Kaptein;Jos L. V. Broers

Frequent Co-Authors

Frans C. S. Ramaekers
Frans C. S. Ramaekers Maastricht University
Raoul C.M. Hennekam
Raoul C.M. Hennekam University of Amsterdam
Johan W. M. Heemskerk
Johan W. M. Heemskerk Maastricht University
Joost J. F. P. Luiken
Joost J. F. P. Luiken Maastricht University
Jan F. C. Glatz
Jan F. C. Glatz Maastricht University
Otto C. Boerman
Otto C. Boerman Radboud University
Ad A.M. Masclee
Ad A.M. Masclee Maastricht University
Carlijn Carlijn Bouten
Carlijn Carlijn Bouten Eindhoven University of Technology
Han G. Brunner
Han G. Brunner Radboud University

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