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Molecular Biology
Singapore
2026
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Genetics and Molecular Biology
Singapore
2024

D-Index & Metrics

Molecular Biology

D-Index
111
Citations
49596
World Ranking
349
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Singapore Leader Award
  • 2025 - Research.com Molecular Biology in Singapore Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Singapore Leader Award
  • 2023 - Research.com Molecular Biology in Singapore Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award

Overview

Colin L. Stewart is affiliated with the Agency for Science, Technology and Research in Singapore. Their research spans across several domains within biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, cardiology and cardiovascular medicine, cell biology, genetics, and hematology.

The primary topics of Stewart's work include:

  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • Mitochondrial Function and Pathology
  • Cellular transport and secretion
  • Microtubule and mitosis dynamics

Stewart has published extensively in a variety of scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stem Cell Reports
  • Cells
  • Human Molecular Genetics
  • Circulation

Their recent papers demonstrate an engagement with topics related to nuclear envelope dynamics and cardiac muscle pathologies, including:

  • "Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy," 2021, Nature Communications
  • "The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the Nucleus," 2020, Annual Review of Genomics and Human Genetics
  • "Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria," 2020, Aging Cell
  • "Lamin A/C Assembly Defects in LMNA-Congenital Muscular Dystrophy Is Responsible for the Increased Severity of the Disease Compared with Emery-Dreifuss Muscular Dystrophy," 2020, Cells
  • "Characterizing arrhythmia using machine learning analysis of Ca2+ cycling in human cardiomyocytes," 2022, Stem Cell Reports

Stewart frequently collaborates with a network of co-authors, several of whom have contributed multiple times to joint research projects. These frequent collaborators include:

  • Brian Burke
  • Hendrikje Werner
  • Yin Loon Lee
  • Alexandre Chojnowski
  • Jinqiu Zhang

Best Publications

  • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

    R L Williams;D J Hilton;S Pease;T A Willson

  • Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor.

    Colin L. Stewart;Petr Kaspar;Lisa J. Brunet;Harshida Bhatt

  • Lamin a truncation in hutchinson-gilford progeria

    Annachiara De Sandre-Giovannoli;Rafaëlle Bernard;Pierre Cau;Claire Navarro

  • Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

    Teresa Sullivan;Diana Escalante-Alcalde;Harshida Bhatt;Miriam Anver

  • IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

    Jeanne Magram;Suzanne E Connaughton;Rajeev R Warrier;Daisy M Carvajal

  • Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction

    Jan Lammerding;P. Christian Schulze;Tomosaburo Takahashi;Serguei Kozlov

  • Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice

    Alain Haziot;Enza Ferrero;Frank Köntgen;Naoki Hijiya

  • Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

    Samuel L. Pfaff;Monica Mendelsohn;Colin L. Stewart;Thomas Edlund

  • LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

    Irina Solovei;Audrey S. Wang;Katharina Thanisch;Christine S. Schmidt

  • Astrocytes Promote Myelination in Response to Electrical Impulses

    Tomoko Ishibashi;Kelly A. Dakin;Beth Stevens;Philip R. Lee

  • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

    Michele M.H. Lau;Claire E.H. Stewart;Ziying Liu;Harshida Bhatt

  • Lamins A and C but not lamin B1 regulate nuclear mechanics

    Jan Lammerding;Loren G. Fong;Julie Y. Ji;Karen Reue;Karen Reue

  • Uterine expression of leukemia inhibitory factor coincides with the onset of blastocyst implantation.

    Harshida Bhatt;Lisa J. Brunet;Colin L. Stewart

  • FVB/N: an inbred mouse strain preferable for transgenic analyses.

    M Taketo;A C Schroeder;L E Mobraaten;K B Gunning

  • Positive selection of natural autoreactive B cells.

    Kyoko Hayakawa;Masanao Asano;Susan A. Shinton;Ming Gui

  • Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

    L. Kwee;H. S. Baldwin;Hong Min Shen;C. L. Stewart

  • Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse.

    Annachiara De Sandre-Giovannoli;Malika Chaouch;Serguei Kozlov;Jean Michel Vallat

  • De novo methylation and expression of retroviral genomes during mouse embryogenesis

    Detlev Jähner;Heidi Stuhlmann;Colin L. Stewart;Klaus Harbers

  • Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

    Douglas Forrest;Michisuke Yuzaki;Holly D. Soares;Lily Ng

  • A perinuclear actin cap regulates nuclear shape

    Shyam B. Khatau;Christopher M. Hale;P. J. Stewart-Hutchinson;Meet S. Patel

Frequent Co-Authors

Brian Burke
Brian Burke Agency for Science, Technology and Research
Nicolas Lévy
Nicolas Lévy Aix-Marseille University
Stephen G. Young
Stephen G. Young University of California, Los Angeles
Roland Foisner
Roland Foisner Medical University of Vienna
Howard J. Worman
Howard J. Worman Columbia University
Jan Lammerding
Jan Lammerding Cornell University
Denis Wirtz
Denis Wirtz Johns Hopkins University
Loren G. Fong
Loren G. Fong University of California, Los Angeles
Gisèle Bonne
Gisèle Bonne Sorbonne University
Richard T. Lee
Richard T. Lee Harvard University

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