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Biology and Biochemistry

D-Index
67
Citations
22526
World Ranking
8076
National Ranking
30

Overview

Brian Burke is affiliated with the Agency for Science, Technology and Research in Singapore. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with a focus on the molecular and cellular mechanisms underlying various biological processes.

Their primary fields of study include Biochemistry, Genetics and Molecular Biology and Medicine. Within these areas, their subfields of expertise encompass Molecular Biology, Cell Biology, Immunology, Cardiology and Cardiovascular Medicine, and Surgery.

Burke's main research topics cover aspects of Nuclear Structure and Function, RNA Research and Splicing, Microtubule and Mitosis Dynamics, Genomics and Chromatin Dynamics, RNA and Protein Synthesis Mechanisms, Cellular Transport and Secretion, as well as Mitochondrial Function and Pathology.

Frequent publication venues where Burke's work appears include bioRxiv (Cold Spring Harbor Laboratory), Circulation, Nature Communications, Human Molecular Genetics, and PLoS Genetics.

Collaborations are a significant aspect of Burke's research, with several frequent co-authors including Colin L. Stewart, Yin Loon Lee, Hendrikje Werner, Alexandre Chojnowski, and Martina Maric.

Selected recent papers authored or co-authored by Brian Burke are:

  • Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy, 2021, Nature Communications
  • Nesprin-1 LINC complexes recruit microtubule cytoskeleton proteins and drive pathology in Lmna-mutant striated muscle, 2022, Human Molecular Genetics
  • AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody, 2021, PLoS Genetics
  • The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein, 2023, The Journal of Cell Biology
  • Nuclear lamins and diabetes mellitus, 2020, STEMedicine

Best Publications

  • A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

    Kyle J. Roux;Kyle J. Roux;Dae In Kim;Dae In Kim;Manfred Raida;Brian Burke

  • Coupling of the nucleus and cytoplasm: Role of the LINC complex

    Melissa Crisp;Qian Liu;Kyle Roux;J.B. Rattner

  • Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

    Teresa Sullivan;Diana Escalante-Alcalde;Harshida Bhatt;Miriam Anver

  • Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

    Lothar Schermelleh;Peter M. Carlton;Sebastian Haase;Lin Shao

  • Functional organization of the nuclear envelope

    Larry Gerace;Brian Burke

  • The molecular structure of human erythrocyte spectrin. Biophysical and electron microscopic studies.

    David M. Shotton;David M. Shotton;Brian E. Burke;Daniel Branton

  • BioID: A Screen for Protein‐Protein Interactions

    Kyle J. Roux;Dae In Kim;Brian Burke

  • The nuclear lamins: flexibility in function

    Brian Burke;Colin L. Stewart

  • The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

    Maria L. Lombardi;Diana E. Jaalouk;Catherine M. Shanahan;Brian Burke

  • Life at the edge: the nuclear envelope and human disease

    Brian Burke;Colin L. Stewart

  • A cell free system to study reassembly of the nuclear envelope at the end of mitosis.

    Brian Burke;Larry Gerace

  • Cytoplasmic Dynein as a Facilitator of Nuclear Envelope Breakdown

    Davide Salina;Khaldon Bodoor;D.Mark Eckley;Trina A. Schroer

  • Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B.

    Colin Stewart;Brian Burke

  • Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

    Kyle J. Roux;Melissa L. Crisp;Qian Liu;Daein Kim

  • Cytoskeleton—membrane interactions

    Pam Cowin;Brian Burke

  • A monoclonal antibody against a 135-K Golgi membrane protein.

    B Burke;G Griffiths;H Reggio;D Louvard

  • Remodelling the walls of the nucleus

    Brian Burke;Jan Ellenberg

  • Blurring the boundary: the nuclear envelope extends its reach.

    Colin L. Stewart;Kyle J. Roux;Brian Burke

  • Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain.

    Sara Nakielny;Sarah Shaikh;Brian Burke;Gideon Dreyfuss

  • Nup358 integrates nuclear envelope breakdown with kinetochore assembly

    Davide Salina;Paul Enarson;J.B. Rattner;Brian Burke

Frequent Co-Authors

Colin L. Stewart
Colin L. Stewart Agency for Science, Technology and Research
Larry Gerace
Larry Gerace Scripps Research Institute
Jerome B. Rattner
Jerome B. Rattner University of Calgary
Jennifer A. Doherty
Jennifer A. Doherty University of Utah
Jennifer L. Stow
Jennifer L. Stow University of Queensland
Gareth Griffiths
Gareth Griffiths University of Oslo
Nelly Panté
Nelly Panté University of British Columbia
Katherine L. Wilson
Katherine L. Wilson Johns Hopkins University School of Medicine
Graham Warren
Graham Warren Medical University of Vienna
Robert D. Goldman
Robert D. Goldman Northwestern University

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