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Biology and Biochemistry

D-Index
84
Citations
27612
World Ranking
3290
National Ranking
1666

Overview

Larry Gerace is affiliated with the Scripps Research Institute in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Molecular Biology and Cell Biology. Additionally, their work intersects with Rehabilitation and Epidemiology, particularly in areas related to Physical Therapy and Sports Therapy.

The main topics covered in their research include:

  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Cellular Transport and Secretion
  • Biotin and Related Studies
  • RNA and Protein Synthesis Mechanisms
  • Genomics and Chromatin Dynamics
  • RNA Regulation and Disease

Larry Gerace's recent scholarly contributions consist of several papers published between 2022 and 2023, including:

  • Lem2 is essential for cardiac development by maintaining nuclear integrity, 2023, Cardiovascular Research
  • Shared and Distinctive Neighborhoods of Emerin and Lamin B Receptor Revealed by Proximity Labeling and Quantitative Proteomics, 2022, Journal of Proteome Research
  • Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope, 2023, Life Science Alliance
  • Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • Lem2 is essential for cardiac development by maintaining nuclear integrity, 2022, bioRxiv (Cold Spring Harbor Laboratory)

Their collaborative work includes frequent co-authorship with the following researchers:

  • Li-Chun Cheng
  • Sabyasachi Baboo
  • Julie A Nguyen
  • Salvador Martínez-Bartolomé
  • Esther Loose

Larry Gerace has published extensively in several venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Life Science Alliance
  • Cardiovascular Research
  • Journal of Proteome Research
  • Disability and Rehabilitation Assistive Technology

Best Publications

  • A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

    Rohit Mahajan;Christian Delphin;Tinglu Guan;Larry Gerace

  • The nuclear envelope lamina is reversibly depolymerized during mitosis

    Larry Gerace;Günter Blobel

  • The nuclear lamina is a meshwork of intermediate-type filaments.

    Ueli Aebi;Ueli Aebi;Julie Cohn;Loren Buhle;Loren Buhle;Larry Gerace

  • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

    Stephen A. Adam;Rachel Sterne Marr;Larry Gerace

  • Functional organization of the nuclear envelope

    Larry Gerace;Brian Burke

  • Nuclear Membrane Proteins with Potential Disease Links Found by Subtractive Proteomics

    Eric C. Schirmer;Laurence Florens;Tinglu Guan;John R. Yates

  • Monoclonal Antibodies Identify a Group of Nuclear Pore Complex Glycoproteins

    Claudette M. Snow;Alayne Senior;Larry Gerace

  • Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor.

    Frauke Melchior;Bryce Paschal;Janice Evans;Larry Gerace

  • Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation

    Roland Foisner;Larry Gerace

  • Adenovirus Protein VI Mediates Membrane Disruption following Capsid Disassembly

    Christopher M. Wiethoff;Harald Wodrich;Larry Gerace;Glen R. Nemerow

  • Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

    G. D. Holt;C. M. Snow;A. Senior;R. S. Haltiwanger

  • Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

    Bryce M. Paschal;Larry Gerace

  • Phosphorylation of the nuclear lamins during interphase and mitosis.

    Y Ottaviano;L Gerace

  • A cell free system to study reassembly of the nuclear envelope at the end of mitosis.

    Brian Burke;Larry Gerace

  • Identification of a major polypeptide of the nuclear pore complex

    L Gerace;Y Ottaviano;C Kondor-Koch

  • A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones.

    H Taniura;C Glass;L Gerace

  • Gradient of Increasing Affinity of Importin β for Nucleoporins along the Pathway of Nuclear Import

    Iris Ben-Efraim;Larry Gerace

  • Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association.

    Rohit Mahajan;Larry Gerace;Frauke Melchior

  • Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope.

    Joanne M. Westendorf;Potu N. Rao;Larry Gerace

  • Integral Membrane Proteins of the Nuclear Envelope Are Dispersed throughout the Endoplasmic Reticulum during Mitosis

    Li Yang;Tinglu Guan;Larry Gerace

Frequent Co-Authors

Eric C. Schirmer
Eric C. Schirmer University of Edinburgh
Frauke Melchior
Frauke Melchior Heidelberg University
Bryce M. Paschal
Bryce M. Paschal University of Virginia
John R. Yates
John R. Yates Scripps Research Institute
Glen R. Nemerow
Glen R. Nemerow Scripps Research Institute
Brian Burke
Brian Burke Agency for Science, Technology and Research
Roland Foisner
Roland Foisner Medical University of Vienna
Guang-Hui Liu
Guang-Hui Liu Chinese Academy of Sciences
Stephen A. Adam
Stephen A. Adam Northwestern University

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