D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 18,586 92 World Ranking 5604 National Ranking 419

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Amino acid
  • Biochemistry

Frauke Melchior focuses on Biochemistry, SUMO enzymes, SUMO protein, Cell biology and Ubiquitin ligase. Her studies in Biochemistry integrate themes in fields like RANBP2, Nuclear protein, Ubiquitin-conjugating enzyme and SUMO-1 Protein. Her research integrates issues of DDB1 and Protein–protein interaction in her study of RANBP2.

She has researched Nuclear protein in several fields, including Ran and Nuclear transport. The SUMO enzymes study which covers Sumoylation Pathway that intersects with Small Ubiquitin-Related Modifier Proteins. The Protein sumoylation, SUMO2 and SUMO binding research she does as part of her general SUMO protein study is frequently linked to other disciplines of science, such as Histone deacetylase activity, therefore creating a link between diverse domains of science.

Her most cited work include:

  • Concepts in sumoylation: a decade on (1322 citations)
  • A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2 (1047 citations)
  • The nucleoporin RanBP2 has SUMO1 E3 ligase activity (676 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in SUMO protein, Cell biology, Biochemistry, SUMO enzymes and RANBP2. Her work deals with themes such as Molecular biology and Lysine, which intersect with SUMO protein. Her studies link Ubiquitin ligase with Cell biology.

Her study in Biochemistry is interdisciplinary in nature, drawing from both Nuclear protein and Consensus site. Her SUMO enzymes research integrates issues from Sumoylation Pathway, SUMO binding, Bioinformatics and Ubiquitin-activating enzyme. Her work in RANBP2 addresses issues such as RanGAP, which are connected to fields such as Computational biology.

She most often published in these fields:

  • SUMO protein (60.68%)
  • Cell biology (53.85%)
  • Biochemistry (52.99%)

What were the highlights of her more recent work (between 2016-2021)?

  • Cell biology (53.85%)
  • SUMO protein (60.68%)
  • Pyrophosphate (3.42%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cell biology, SUMO protein, Pyrophosphate, Proteome and Signal transduction. Her work on Proteasome as part of general Cell biology research is often related to Basal body, thus linking different fields of science. The study incorporates disciplines such as Lysine and Phosphorylation in addition to SUMO protein.

Her Signal transduction research is multidisciplinary, incorporating elements of Hypoxia, Repressor, Epidermal growth factor receptor and SUMO2. Metabolism is a subfield of Biochemistry that Frauke Melchior explores. Particularly relevant to Yeast is her body of work in Biochemistry.

Between 2016 and 2021, her most popular works were:

  • Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases (55 citations)
  • Control of SUMO and Ubiquitin by ROS: Signaling and disease implications (20 citations)
  • IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs. (12 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Amino acid
  • Genetics

Cell biology, SUMO protein, Proteasome, SUMO2 and In vitro are her primary areas of study. Frauke Melchior interconnects Innate immune system and Cysteine in the investigation of issues within Cell biology. Her Innate immune system research includes elements of Chemokine and Cytokine.

Frauke Melchior combines subjects such as Oxidative stress, Isopeptide bond, Lysine and Cell signaling with her study of Cysteine. The SUMO2 study combines topics in areas such as Proteome, Hypoxia, Transcriptional regulation and Signal transduction. Her In vitro study integrates concerns from other disciplines, such as HEK 293 cells, Crosstalk, Promyelocytic leukemia protein and Enzyme.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Concepts in sumoylation: a decade on

Ruth Geiss-Friedlander;Frauke Melchior.
Nature Reviews Molecular Cell Biology (2007)

1783 Citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

Rohit Mahajan;Christian Delphin;Tinglu Guan;Larry Gerace.
Cell (1997)

1668 Citations

The nucleoporin RanBP2 has SUMO1 E3 ligase activity

Andrea Pichler;Andreas Gast;Jacob S. Seeler;Anne Dejean.
Cell (2002)

1053 Citations

SUMO--nonclassical ubiquitin.

Frauke Melchior.
Annual Review of Cell and Developmental Biology (2000)

1045 Citations

Sumoylation: A Regulatory Protein Modification in Health and Disease

Annette Flotho;Frauke Melchior.
Annual Review of Biochemistry (2013)

969 Citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor.

Frauke Melchior;Bryce Paschal;Janice Evans;Larry Gerace.
Journal of Cell Biology (1993)

640 Citations

PIASy, a nuclear matrix–associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Shrikesh Sachdev;Laurakay Bruhn;Heidemarie Sieber;Andrea Pichler.
Genes & Development (2001)

634 Citations

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

Martin Beck;Friedrich Förster;Mary Ecke;Jürgen M. Plitzko.
Science (2004)

588 Citations

SUMO: ligases, isopeptidases and nuclear pores.

Frauke Melchior;Marion Schergaut;Andrea Pichler.
Trends in Biochemical Sciences (2003)

520 Citations

Structure determination of the small ubiquitin-related modifier SUMO-1.

Peter Bayer;Andreas Arndt;Susanne Metzger;Rohit Mahajan.
Journal of Molecular Biology (1998)

518 Citations

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