2026 Frauke Melchior: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	56	14157	13020	998	933	114	20439

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

14157

13020

998

933

114

20439

Biology and Biochemistry

D-Index

Citations

20439

World Ranking

14157

National Ranking

998

Overview

Frauke Melchior is affiliated with Heidelberg University in Germany and has a focused research portfolio primarily within the field of Biochemistry, Genetics and Molecular Biology. Their work particularly concentrates on Molecular Biology, with substantial contributions also in Cell Biology, Cancer Research, Biochemistry, and Genetics.

The scientist's research explores various topics related to protein regulation and cellular mechanisms. These include:

Ubiquitin and proteasome pathways
Cancer, hypoxia, and metabolism
Heat shock proteins research
Protein degradation and inhibitors
Microtubule and mitosis dynamics
Lipid metabolism and biosynthesis
Glycosylation and glycoproteins research

Frauke Melchior has coauthored publications with several frequent collaborators, including Sina V. Barysch, Nicolas Stankovic-Valentin, Henning Urlaub, Szymon W. Kmiecik, and Katarzyna Drzewicka. This network of collaboration supports a range of studies within molecular and cell biology contexts.

Publications by Frauke Melchior have appeared in a variety of scientific journals, with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), EMBO Reports, Journal of Biological Chemistry, Cell Death and Disease, and The EMBO Journal.

Recent notable papers by Frauke Melchior include:

Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling (2021), published in EMBO Reports
Heat shock transcription factor 1 is SUMOylated in the activated trimeric state (2021), published in Journal of Biological Chemistry
The Sumo proteome of proliferating and neuronal-differentiating cells reveals Utf1 among key Sumo targets involved in neurogenesis (2021), published in Cell Death and Disease
SCF ^Fbxw5 targets kinesin-13 proteins to facilitate ciliogenesis (2021), published in The EMBO Journal
Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism (2023), published in EMBO Reports

Best Publications

Concepts in sumoylation: a decade on

Ruth Geiss-Friedlander;Frauke Melchior

2077
Citations
A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

Rohit Mahajan;Christian Delphin;Tinglu Guan;Larry Gerace

1758
Citations
Sumoylation: A Regulatory Protein Modification in Health and Disease

Annette Flotho;Frauke Melchior

1321
Citations
The nucleoporin RanBP2 has SUMO1 E3 ligase activity

Andrea Pichler;Andreas Gast;Jacob S. Seeler;Anne Dejean

1137
Citations
SUMO--nonclassical ubiquitin.

Frauke Melchior

1090
Citations
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor.

Frauke Melchior;Bryce Paschal;Janice Evans;Larry Gerace

702
Citations
PIASy, a nuclear matrix–associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Shrikesh Sachdev;Laurakay Bruhn;Heidemarie Sieber;Andrea Pichler

664
Citations
Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

Martin Beck;Friedrich Förster;Mary Ecke;Jürgen M. Plitzko

648
Citations
Structure determination of the small ubiquitin-related modifier SUMO-1.

Peter Bayer;Andreas Arndt;Susanne Metzger;Rohit Mahajan

566
Citations
SUMO: ligases, isopeptidases and nuclear pores.

Frauke Melchior;Marion Schergaut;Andrea Pichler

549
Citations
Regulation of SUMOylation by Reversible Oxidation of SUMO Conjugating Enzymes

Guillaume Bossis;Frauke Melchior

502
Citations
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.

Olivier Kirsh;Jacob-S. Seeler;Andrea Pichler;Andreas Gast

447
Citations
Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association.

Rohit Mahajan;Larry Gerace;Frauke Melchior

401
Citations
Transcription factor Sp3 is silenced through SUMO modification by PIAS1

Alexandra Sapetschnig;Grigore Rischitor;Harald Braun;Andreas Doll

338
Citations
Mechanisms of nuclear protein import

Frauke Melchior;Larry Gerace

328
Citations
Sumoylation inhibits α-synuclein aggregation and toxicity

Petranka Krumova;Erik Meulmeester;Manuel Garrido;Marilyn Tirard

321
Citations
Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

Daniël Splinter;Marvin E. Tanenbaum;Arne Lindqvist;Dick Jaarsma

316
Citations
Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25

Erik Meulmeester;Marion Kunze;He Hsuan Hsiao;Henning Urlaub

311
Citations
SUMO modification of the ubiquitin-conjugating enzyme E2-25K

Andrea Pichler;Andrea Pichler;Puck Knipscheer;Edith Oberhofer;Willem J van Dijk

272
Citations
Detecting endogenous SUMO targets in mammalian cells and tissues.

Janina Becker;Sina V. Barysch;Samir Karaca;Claudia Dittner;Claudia Dittner

264
Citations