World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
19713
World Ranking
8524
National Ranking
230

Overview

Antonio Moschetta is affiliated with the University of Bari Aldo Moro in Italy. Their research spans multiple domains within medicine, biochemistry, genetics, and molecular biology, with a strong emphasis on understanding the mechanisms underpinning metabolic and liver diseases.

The scientist's recent publications demonstrate focused investigations in topics such as gut microbiota, metabolic pathways, and inflammation. Selected papers include:

  • Gut microbiota in the pathogenesis and therapeutic approaches of diabetes, 2023, published in EBioMedicine
  • Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor, 2020, EBioMedicine
  • Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH, 2021, Cellular and Molecular Gastroenterology and Hepatology
  • Visceral Adiposity and Cancer: Role in Pathogenesis and Prognosis, 2021, Nutrients
  • The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis, 2023, Nature Communications

Their main research fields cover medicine and biochemistry, genetics and molecular biology. Subfields addressed by their work include epidemiology, molecular biology, surgery, physiology, and oncology.

Antonio Moschetta's core research topics are:

  • Liver Disease Diagnosis and Treatment
  • Diet and metabolism studies
  • Cholesterol and Lipid Metabolism
  • Cancer, Lipids, and Metabolism
  • Gut microbiota and health
  • Liver Diseases and Immunity
  • Drug Transport and Resistance Mechanisms

Frequent collaborators in their research include Marica Cariello, Lucilla Crudele, Raffaella Maria Gadaleta, Elena Piccinin, and Carlo De Matteis. This network of co-authors has contributed substantially to the progression of their shared research topics.

The scientist's work appears regularly in specialized journals, with frequent publications appearing in:

  • Nutrients
  • Scientific Reports
  • Liver International
  • EBioMedicine
  • International Journal of Molecular Sciences

Best Publications

  • Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

    Takeshi Inagaki;Mihwa Choi;Antonio Moschetta;Li Peng

  • Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

    Mitsuhiro Watanabe;Sander M. Houten;Li Wang;Antonio Moschetta

  • Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.

    Takeshi Inagaki;Antonio Moschetta;Youn Kyoung Lee;Li Peng

  • Cholesterol gallstone disease

    Piero Portincasa;Antonio Moschetta;Giuseppe Palasciano

  • Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

    Raffaella M Gadaleta;Karel J van Erpecum;Bas Oldenburg;Ellen C L Willemsen

  • REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

    Gwendal Le Martelot;Thierry Claudel;David Gatfield;Olivier Schaad

  • Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis.

    Ignazio Grattagliano;Vincenzo O. Palmieri;Piero Portincasa;Antonio Moschetta

  • Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23

    Chiara Degirolamo;Carlo Sabbà;Antonio Moschetta

  • Prevention of cholesterol gallstone disease by FXR agonists in a mouse model

    Antonio Moschetta;Angie L Bookout;David J Mangelsdorf

  • Microbiota Modification with Probiotics Induces Hepatic Bile Acid Synthesis via Downregulation of the Fxr-Fgf15 Axis in Mice

    Chiara Degirolamo;Stefania Rainaldi;Fabiola Bovenga;Stefania Murzilli

  • Identification of a hormonal basis for gallbladder filling

    Mihwa Choi;Antonio Moschetta;Angie L Bookout;Li Peng

  • Mitochondrial function - gatekeeper of intestinal epithelial cell homeostasis.

    Eva Rath;Antonio Moschetta;Dirk Haller

  • Deciphering the nuclear bile acid receptor FXR paradigm.

    Salvatore Modica;Raffaella M. Gadaleta;Antonio Moschetta

  • Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.

    Salvatore Modica;Michele Petruzzelli;Elena Bellafante;Stefania Murzilli

  • Aminotransferase activity in morbid and uncomplicated obesity: predictive role of fasting insulin.

    Gianluca Iacobellis;Antonio Moschetta;Raffaella Buzzetti;Maria Cristina Ribaudo

  • Expression of ABCG5 and ABCG8 Is Required for Regulation of Biliary Cholesterol Secretion

    Liqing Yu;Sarita Gupta;Fang Xu;Amy D.B. Liverman

  • Nuclear bile acid receptor FXR protects against intestinal tumorigenesis.

    Salvatore Modica;Stefania Murzilli;Lorena Salvatore;Daniel R. Schmidt

  • Bile acids and colon cancer: Solving the puzzle with nuclear receptors

    Chiara Degirolamo;Salvatore Modica;Giuseppe Palasciano;Antonio Moschetta

  • Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis.

    Giuseppe Lo Sasso;Stefania Murzilli;Lorena Salvatore;Ilenia D'Errico

  • Uncoupling nuclear receptor LXR and cholesterol metabolism in cancer

    Fabiola Bovenga;Carlo Sabbà;Antonio Moschetta

Frequent Co-Authors

Piero Portincasa
Piero Portincasa University of Bari Aldo Moro
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center
Albert K. Groen
Albert K. Groen University of Amsterdam
Steven A. Kliewer
Steven A. Kliewer The University of Texas Southwestern Medical Center
Aldo Roda
Aldo Roda University of Bologna
Cristiano Simone
Cristiano Simone University of Bari Aldo Moro
Laura Calabresi
Laura Calabresi University of Milan
Joyce J. Repa
Joyce J. Repa The University of Texas Southwestern Medical Center
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
James M. Ntambi
James M. Ntambi University of Wisconsin–Madison

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